Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:1000; loading ...; fig 5a
| Siu M, Jiang Y, Wang J, Leung T, Ngu S, Cheung A, et al. PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling. Oncogenesis. 2020;9:24 pubmed publisher
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- immunocytochemistry; mouse; 1:100; loading ...; fig 6e
- western blot; mouse; 1:1000; loading ...; fig 4b
| Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 13c
| Mammone T, Chidlow G, Casson R, Wood J. Improved immunohistochemical detection of phosphorylated mitogen-activated protein kinases in the injured rat optic nerve head. Histochem Cell Biol. 2019;151:435-456 pubmed publisher
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- western blot; human; loading ...; fig 4d
| Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, et al. TFAM is a novel mediator of immunogenic cancer cell death. Oncoimmunology. 2018;7:e1431086 pubmed publisher
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- western blot; mouse; loading ...; fig 6d
| Huang M, Qi W, Fang S, Jiang P, Yang C, Mo Y, et al. Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42. Neurotherapeutics. 2018;15:728-741 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 1g
| Yungher B, Ribeiro M, Park K. Regenerative Responses and Axon Pathfinding of Retinal Ganglion Cells in Chronically Injured Mice. Invest Ophthalmol Vis Sci. 2017;58:1743-1750 pubmed publisher
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- immunocytochemistry; human; loading ...; fig s1
| Loo L, Bougen Zhukov N, Tan W. Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. Sci Rep. 2017;7:43541 pubmed publisher
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- western blot; mouse; loading ...; fig s5e
| Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher
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- immunocytochemistry; human; 1:800; fig 6g
| Fallahi Sichani M, Becker V, Izar B, Baker G, Lin J, Boswell S, et al. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Mol Syst Biol. 2017;13:905 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 3e
| Sommer J, Mahli A, Freese K, Schiergens T, Kuecuekoktay F, Teufel A, et al. Analysis of molecular mechanisms of 5-fluorouracil-induced steatosis and inflammation in vitro and in mice. Oncotarget. 2017;8:13059-13072 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 1e
| Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
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- western blot; human; loading ...; fig 4c
| Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 5d
| Zhang K, Cai H, Gao S, Yang G, Deng H, Xu G, et al. TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals. Oncotarget. 2016;7:69436-69449 pubmed publisher
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- western blot; human; fig 1b
| Boß M, Newbatt Y, Gupta S, Collins I, Brüne B, Namgaladze D. AMPK-independent inhibition of human macrophage ER stress response by AICAR. Sci Rep. 2016;6:32111 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig s3a
| Xiang N, Liu J, Liao Y, Huang Y, Wu Z, Bai Z, et al. Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway. Sci Rep. 2016;6:27583 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig 4
| Kim B, Silverman S, Liu Y, Wordinger R, Pang I, Clark A. In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells. Mol Neurodegener. 2016;11:30 pubmed publisher
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- western blot; human; 1:1000; fig 6
- immunoprecipitation; mouse; fig 8
- western blot; mouse; 1:1000; fig 5
| Yang Y, Huycke M, Herman T, Wang X. Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. Oncogene. 2016;35:5795-5806 pubmed publisher
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- western blot; human; fig 6
| An X, Zhao Z, Luo Y, Zhang R, Tang X, Hao D, et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget. 2016;7:24719-33 pubmed publisher
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- western blot; mouse; 1:1000; fig s4
| Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher
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- western blot; mouse; fig s1
| Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
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- western blot; dogs; 1:1000; fig 1b
| Neumann Z, Pondenis H, Masyr A, Byrum M, Wycislo K, Fan T. The Association of Endothelin-1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma. J Vet Intern Med. 2015;29:1584-94 pubmed publisher
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- immunohistochemistry - paraffin section; zebrafish ; 1:200; fig 5
- immunohistochemistry - paraffin section; human; 1:200; fig 5
| Evason K, Francisco M, Juric V, Balakrishnan S, Lopez Pazmino M, Gordan J, et al. Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish. PLoS Genet. 2015;11:e1005305 pubmed publisher
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| Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
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- western blot; rat; 1:1500
| Heinen A, Beyer F, Tzekova N, Hartung H, Küry P. Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype. Exp Neurol. 2015;271:25-35 pubmed publisher
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| Bhushan S, Tchatalbachev S, Lu Y, Fröhlich S, Fijak M, Vijayan V, et al. Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol. 2015;194:5455-64 pubmed publisher
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- immunocytochemistry; human; 1:800; fig 5
| Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
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- western blot; human; 1:200; fig 3b
| Chung Y, Kim H, Park S, Yoon J, Kim M, Nam S, et al. Transcriptome analysis reveals that Müllerian inhibiting substance regulates signaling pathways that contribute to endometrial carcinogenesis. Int J Oncol. 2015;46:2039-46 pubmed publisher
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- immunohistochemistry - paraffin section; zebrafish ; 1:100
- chromatin immunoprecipitation; zebrafish
| de Oliveira S, Boudinot P, Calado Ã, Mulero V. Duox1-derived H2O2 modulates Cxcl8 expression and neutrophil recruitment via JNK/c-JUN/AP-1 signaling and chromatin modifications. J Immunol. 2015;194:1523-33 pubmed publisher
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- immunocytochemistry; African green monkey; fig s7g
- immunocytochemistry; human; fig s7g
| Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
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- flow cytometry; human; loading ...; fig 5b
| Guzmán E, Maers K, Roberts J, Kemami Wangun H, Harmody D, Wright A. The marine natural product microsclerodermin A is a novel inhibitor of the nuclear factor kappa B and induces apoptosis in pancreatic cancer cells. Invest New Drugs. 2015;33:86-94 pubmed publisher
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- western blot; human; 1:1000; fig 4
| Lin C, Chen P, Hsu L, Kuo D, Chu S, Hsieh Y. Inhibition of the invasion and migration of renal carcinoma 786‑o‑si3 cells in vitro and in vivo by Koelreuteria formosana extract. Mol Med Rep. 2014;10:3334-42 pubmed publisher
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| Wang R, Wang Y, Gao Z, Qu X. The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. Drug Discov Ther. 2014;8:25-32 pubmed
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- immunohistochemistry - paraffin section; mouse; 1:100
- western blot; mouse; 1:1000
| Dorn C, Engelmann J, Saugspier M, Koch A, Hartmann A, Müller M, et al. Increased expression of c-Jun in nonalcoholic fatty liver disease. Lab Invest. 2014;94:394-408 pubmed publisher
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- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| Delgado O, Batten K, Richardson J, Xie X, Gazdar A, Kaisani A, et al. Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res. 2014;20:1610-22 pubmed publisher
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| Chen Y, Thang M, Chan Y, Huang Y, Ma N, Yu A, et al. Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PLoS ONE. 2013;8:e82751 pubmed publisher
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- western blot; mouse; 1:2000
| Okami N, Narasimhan P, Yoshioka H, Sakata H, Kim G, Jung J, et al. Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase. J Cereb Blood Flow Metab. 2013;33:106-14 pubmed publisher
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| Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
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| Aubrecht T, Faden A, Sabirzhanov B, Glaser E, Roelofs B, Polster B, et al. Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury. Cell Death Dis. 2018;9:1121 pubmed publisher
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| Shimobayashi M, Albert V, Woelnerhanssen B, Frei I, Weissenberger D, Meyer Gerspach A, et al. Insulin resistance causes inflammation in adipose tissue. J Clin Invest. 2018;128:1538-1550 pubmed publisher
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| Robitaille A, Caron E, Zucchini N, Mukawera E, Adam D, Mariani M, et al. DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection. Sci Rep. 2017;7:17388 pubmed publisher
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| Wynne J, Todd S, Boyd V, Tachedjian M, Klein R, Shiell B, et al. Comparative Transcriptomics Highlights the Role of the Activator Protein 1 Transcription Factor in the Host Response to Ebolavirus. J Virol. 2017;91: pubmed publisher
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| Satterfield L, Shuck R, Kurenbekova L, Allen Rhoades W, Edwards D, Huang S, et al. miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. Int J Cancer. 2017;141:2062-2075 pubmed publisher
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| Feng T, Dzieran J, Yuan X, Dropmann A, Maass T, Teufel A, et al. Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice. Oncogenesis. 2017;6:e294 pubmed publisher
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| Metheetrairut C, Adams B, Nallur S, Weidhaas J, Slack F. cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation. Oncogene. 2017;36:512-524 pubmed publisher
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| O Hara S, Garcea R. Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection. MBio. 2016;7: pubmed publisher
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| Gari H, Degala G, Lucia M, Lambert J. Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth. Oncogenesis. 2016;5:e255 pubmed publisher
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| Hao Y, Frey E, Yoon C, Wong H, Nestorovski D, Holzman L, et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. elife. 2016;5: pubmed publisher
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| Koch A, Lang S, Wild P, Gantner S, Mahli A, Spanier G, et al. Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells. Oncotarget. 2015;6:32748-60 pubmed publisher
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| Kao C, Chao A, Tsai C, Chuang W, Huang W, Chen G, et al. Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation. Cell Death Dis. 2014;5:e1510 pubmed publisher
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| Tomé M, Sepúlveda J, Delgado M, Andrades J, Campisi J, Gonzalez M, et al. miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity. Stem Cells. 2014;32:2229-44 pubmed publisher
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| Gauron C, Rampon C, Bouzaffour M, Ipendey E, Teillon J, Volovitch M, et al. Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed. Sci Rep. 2013;3:2084 pubmed publisher
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| Guzman E, Maher M, Temkin A, Pitts T, Wright A. Spongiatriol inhibits nuclear factor kappa B activation and induces apoptosis in pancreatic cancer cells. Mar Drugs. 2013;11:1140-51 pubmed publisher
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| Bhushan S, Hossain H, Lu Y, Geisler A, Tchatalbachev S, Mikulski Z, et al. Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege. PLoS ONE. 2011;6:e28452 pubmed publisher
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| Ono Y, Hayashida T, Konagai A, Okazaki H, Miyao K, Kawachi S, et al. Direct inhibition of the transforming growth factor-? pathway by protein-bound polysaccharide through inactivation of Smad2 signaling. Cancer Sci. 2012;103:317-24 pubmed publisher
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