| Published Application/Species/Dilution | Reference |
|---|
- western blot (knockdown validation); rat; fig 3
| Zhang Y, Hu S, Chen Y, Guo M, Wang S. Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway. Int J Mol Med. 2016;38:1055-62 pubmed publisher |
- western blot; mouse; 1:1000; fig 7D
| Liu S, Li Q, Zhang M, Mao-Ying Q, Hu L, Wu G, et al. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Sci Rep. 2016;6:28956 pubmed publisher |
- immunocytochemistry; human; fig 6
- western blot; human; fig 2d
| Roncero A, Lopez-Nieva P, Cobos-Fernández M, Villa-Morales M, González-Sánchez L, Lopez-Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed publisher |
- western blot; human; fig 5
| Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed publisher |
- western blot; human; fig 1c
| Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon B, Lee J, et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J Biol Chem. 2016;291:7357-72 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed |
- western blot; human; fig 4
| Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 2015;6:14796-813 pubmed |
- immunohistochemistry - paraffin section; human; 1:800
| Andreasen S, Therkildsen M, Grauslund M, Friis-Hansen L, Wessel I, Homøe P. Activation of the interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma of the parotid gland. APMIS. 2015;123:706-15 pubmed publisher |
- western blot; human; fig 3
| Wu L, Guo L, Liang Y, Liu X, Jiang L, Wang L. Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway. Oncol Rep. 2015;34:3311-7 pubmed publisher |
| Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher |
| Kopaliani I, Martin M, Zatschler B, Bortlik K, Müller B, Deussen A. Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta. Basic Res Cardiol. 2014;109:419 pubmed publisher |
| Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, et al. The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes. PLoS ONE. 2014;9:e111097 pubmed publisher |
| Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed |
| Wang S, Chen X, Tang M. MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2. Oncol Rep. 2014;32:2824-30 pubmed publisher |
| Ringel F, Kaeda J, Schwarz M, Oberender C, Grille P, Dorken B, et al. Effects of Jak2 type 1 inhibitors NVP-BSK805 and NVP-BVB808 on Jak2 mutation-positive and Bcr-Abl-positive cell lines. Acta Haematol. 2014;132:75-86 pubmed publisher |
| Garcia K, Sun Z, Mattson E, Li L, Smyth K, Xiao Z. IL-12 is required for mTOR regulation of memory CTLs during viral infection. Genes Immun. 2014;15:413-23 pubmed publisher |
| Wu A, Dalvi P, Lu X, Yang M, Riddick D, Matthews J, et al. Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells. Mol Pharmacol. 2013;83:377-88 pubmed publisher |
| Lo J, Patel V, Wang Z, Levasseur J, Kaufman S, Penninger J, et al. Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats. Exp Physiol. 2013;98:109-22 pubmed publisher |
| Rinaldi C, Rinaldi P, Alagia A, Gemei M, Esposito N, Formiggini F, et al. Preferential nuclear accumulation of JAK2V617F in CD34+ but not in granulocytic, megakaryocytic, or erythroid cells of patients with Philadelphia-negative myeloproliferative neoplasia. Blood. 2010;116:6023-6 pubmed publisher |
| Girodon F, Steinkamp M, Cleyrat C, Hermouet S, Wilson B. Confocal imaging studies cast doubt on nuclear localization of JAK2V617F. Blood. 2011;118:2633-4 pubmed |
| Metlakunta A, Sahu M, Yasukawa H, Dhillon S, Belsham D, Yoshimura A, et al. Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling. Am J Physiol Regul Integr Comp Physiol. 2011;300:R1185-93 pubmed publisher |
| Pulikkan J, Madera D, Xue L, Bradley P, Landrette S, Kuo Y, et al. Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling. Blood. 2012;120:868-79 pubmed publisher |
| Singh S, Verma R, Pradeep A, Leu K, Mortensen R, Young P, et al. Dynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR alleles. PLoS ONE. 2012;7:e29064 pubmed publisher |
| Bhattacharyya S, Zhao Y, Kay T, Muglia L. Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation. Proc Natl Acad Sci U S A. 2011;108:9554-9 pubmed publisher |
