| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:5000; loading ...; fig 1a
| Gammons M, Rutherford T, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016;129:3892-3902 pubmed |
- immunoprecipitation; human; loading ...; fig 2e
| Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S. The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. elife. 2017;6: pubmed publisher |
- western blot; human; loading ...; fig s5
| Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig s2b
- western blot; human; 1:1000; fig s4a
| Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet. 2016;12:e1006217 pubmed publisher |
- immunohistochemistry; mouse; fig 6
| Gegg M, Böttcher A, Burtscher I, Hasenoeder S, Van Campenhout C, Aichler M, et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. elife. 2014;3: pubmed publisher |
- western blot; human; 1:2000; fig 8
| Liu C, Lin C, Gao C, May Simera H, Swaroop A, Li T. Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a. Biol Open. 2014;3:861-70 pubmed publisher |
- western blot; human; 1:1000
| Kilander M, Petersen J, Andressen K, Ganji R, Levy F, Schuster J, et al. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. FASEB J. 2014;28:2293-305 pubmed publisher |
| Abou Jaoudé W, Traynard P, Monteiro P, Saez Rodriguez J, Helikar T, Thieffry D, et al. Logical Modeling and Dynamical Analysis of Cellular Networks. Front Genet. 2016;7:94 pubmed publisher |
| Di Camillo B, Carlon A, Eduati F, Toffolo G. A rule-based model of insulin signalling pathway. BMC Syst Biol. 2016;10:38 pubmed publisher |
| Chen H, Wang G, Simha R, Du C, Zeng C. Boolean Models of Biological Processes Explain Cascade-Like Behavior. Sci Rep. 2016;7:20067 pubmed publisher |
| Marmiesse L, Peyraud R, Cottret L. FlexFlux: combining metabolic flux and regulatory network analyses. BMC Syst Biol. 2015;9:93 pubmed publisher |
| Hanna E, Zaki N, Amin A. Detecting Protein Complexes in Protein Interaction Networks Modeled as Gene Expression Biclusters. PLoS ONE. 2015;10:e0144163 pubmed publisher |
| Shopera T, Henson W, Ng A, Lee Y, Ng K, Moon T. Robust, tunable genetic memory from protein sequestration combined with positive feedback. Nucleic Acids Res. 2015;43:9086-94 pubmed publisher |
| Terfve C, Wilkes E, Casado P, Cutillas P, Saez Rodriguez J. Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data. Nat Commun. 2015;6:8033 pubmed publisher |
| Chasapi A, Wachowicz P, Niknejad A, Collin P, Krapp A, Cano E, et al. An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation. PLoS ONE. 2015;10:e0134214 pubmed publisher |
| Grieb M, Burkovski A, Sträng J, Kraus J, Groß A, Palm G, et al. Predicting Variabilities in Cardiac Gene Expression with a Boolean Network Incorporating Uncertainty. PLoS ONE. 2015;10:e0131832 pubmed publisher |
| Yousef K, Streck A, Schütte C, Siebert H, Hengge R, von Kleist M. Logical-continuous modelling of post-translationally regulated bistability of curli fiber expression in Escherichia coli. BMC Syst Biol. 2015;9:39 pubmed publisher |
| Kerkhofs J, Geris L. A Semiquantitative Framework for Gene Regulatory Networks: Increasing the Time and Quantitative Resolution of Boolean Networks. PLoS ONE. 2015;10:e0130033 pubmed publisher |
| Stavrakas V, Melas I, Sakellaropoulos T, Alexopoulos L. Network reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theory. PLoS ONE. 2015;10:e0128411 pubmed publisher |
| Türei D, Földvári Nagy L, Fazekas D, Módos D, Kubisch J, Kadlecsik T, et al. Autophagy Regulatory Network - a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy. Autophagy. 2015;11:155-65 pubmed publisher |
| Conroy B, Herek T, Shew T, Latner M, Larson J, Allen L, et al. Design, Assessment, and in vivo Evaluation of a Computational Model Illustrating the Role of CAV1 in CD4(+) T-lymphocytes. Front Immunol. 2014;5:599 pubmed publisher |
| Habibi I, Emamian E, Abdi A. Advanced fault diagnosis methods in molecular networks. PLoS ONE. 2014;9:e108830 pubmed publisher |
| Espinal EnrÃquez J, Darszon A, Guerrero A, MartÃnez Mekler G. In silico determination of the effect of multi-target drugs on calcium dynamics signaling network underlying sea urchin spermatozoa motility. PLoS ONE. 2014;9:e104451 pubmed publisher |
| Rharass T, Lemcke H, Lantow M, Kuznetsov S, Weiss D, Panàkovà D. Ca2+-mediated mitochondrial reactive oxygen species metabolism augments Wnt/?-catenin pathway activation to facilitate cell differentiation. J Biol Chem. 2014;289:27937-51 pubmed publisher |
| Habibi I, Emamian E, Abdi A. Quantitative analysis of intracellular communication and signaling errors in signaling networks. BMC Syst Biol. 2014;8:89 pubmed publisher |
| Choi K, Ghaddar B, Moya C, Shi H, Sridharan G, Lee K, et al. Analysis of transcription factor network underlying 3T3-L1 adipocyte differentiation. PLoS ONE. 2014;9:e100177 pubmed publisher |
| Duan G, Walther D, Schulze W. Reconstruction and analysis of nutrient-induced phosphorylation networks in Arabidopsis thaliana. Front Plant Sci. 2013;4:540 pubmed publisher |
| Iorio F, Saez Rodriguez J, di Bernardo D. Network based elucidation of drug response: from modulators to targets. BMC Syst Biol. 2013;7:139 pubmed publisher |
| Büchel F, Rodriguez N, Swainston N, Wrzodek C, Czauderna T, Keller R, et al. Path2Models: large-scale generation of computational models from biochemical pathway maps. BMC Syst Biol. 2013;7:116 pubmed publisher |
| Chowdhury S, Pradhan R, Sarkar R. Structural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancer. PLoS ONE. 2013;8:e69132 pubmed publisher |
| Samaga R, Klamt S. Modeling approaches for qualitative and semi-quantitative analysis of cellular signaling networks. Cell Commun Signal. 2013;11:43 pubmed publisher |
| Helikar T, Kochi N, Kowal B, Dimri M, Naramura M, Raja S, et al. A comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells. PLoS ONE. 2013;8:e61757 pubmed publisher |
| Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton J. Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. PLoS ONE. 2012;7:e50881 pubmed publisher |
| Mitsos A, Melas I, Morris M, Saez Rodriguez J, Lauffenburger D, Alexopoulos L. Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways. PLoS ONE. 2012;7:e50085 pubmed publisher |
| Helikar T, Kowal B, Madrahimov A, Shrestha M, Pedersen J, Limbu K, et al. Bio-logic builder: a non-technical tool for building dynamical, qualitative models. PLoS ONE. 2012;7:e46417 pubmed publisher |
| Terfve C, Cokelaer T, Henriques D, MacNamara A, Gonçalves E, Morris M, et al. CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms. BMC Syst Biol. 2012;6:133 pubmed publisher |
| Clarke D, Morris M, Lauffenburger D. Normalization and statistical analysis of multiplexed bead-based immunoassay data using mixed-effects modeling. Mol Cell Proteomics. 2013;12:245-62 pubmed publisher |
| Blair R, Trichler D, Gaille D. Mathematical and statistical modeling in cancer systems biology. Front Physiol. 2012;3:227 pubmed publisher |
| Nassiri I, Masoudi Nejad A, Jalili M, Moeini A. Nonparametric simulation of signal transduction networks with semi-synchronized update. PLoS ONE. 2012;7:e39643 pubmed publisher |
| Siddle K. Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances. Front Endocrinol (Lausanne). 2012;3:34 pubmed publisher |
| Kerkhofs J, Roberts S, Luyten F, Van Oosterwyck H, Geris L. Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype. PLoS ONE. 2012;7:e34729 pubmed publisher |
| Kirouac D, Saez Rodriguez J, Swantek J, Burke J, Lauffenburger D, Sorger P. Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks. BMC Syst Biol. 2012;6:29 pubmed publisher |
| Huard J, Mueller S, Gilles E, Klingmuller U, Klamt S. An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes. FEBS J. 2012;279:3290-313 pubmed publisher |
| Sun Y, Patel A, Kumar P, Chen Z. Role of ABC transporters in cancer chemotherapy. Chin J Cancer. 2012;31:51-7 pubmed publisher |
| Zhou T. Network systems biology for targeted cancer therapies. Chin J Cancer. 2012;31:134-41 pubmed publisher |
| Morris M, Shriver Z, Sasisekharan R, Lauffenburger D. Querying quantitative logic models (Q2LM) to study intracellular signaling networks and cell-cytokine interactions. Biotechnol J. 2012;7:374-86 pubmed publisher |
| Wang B, Kitney R, Joly N, Buck M. Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology. Nat Commun. 2011;2:508 pubmed publisher |
| Espinal J, Aldana M, Guerrero A, Wood C, Darszon A, Martínez Mekler G. Discrete dynamics model for the speract-activated Ca2+ signaling network relevant to sperm motility. PLoS ONE. 2011;6:e22619 pubmed publisher |
| Melas I, Mitsos A, Messinis D, Weiss T, Alexopoulos L. Combined logical and data-driven models for linking signalling pathways to cellular response. BMC Syst Biol. 2011;5:107 pubmed publisher |
| Liang J, Fu Y, Cruciat C, Jia S, Wang Y, Tong Z, et al. Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Mol Cell Biol. 2011;31:2577-90 pubmed publisher |
| Kraeutler M, Soltis A, Saucerman J. Modeling cardiac ?-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model. BMC Syst Biol. 2010;4:157 pubmed publisher |
| Guo J, Cagatay T, Zhou G, Chan C, Blythe S, Suyama K, et al. Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling. PLoS ONE. 2009;4:e7982 pubmed publisher |
