product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PKM2 Antibody
catalog :
3198
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 2a
Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  • western blot; mouse; loading ...; fig 3g
Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed publisher
  • western blot; human; 1:1000; fig 3e
Carpentieri A, Cozzoli E, Scimeca M, Bonanno E, Sardanelli A, Gambacurta A. Differentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitor. Cell Death Dis. 2015;6:e1974 pubmed publisher
  • western blot; human; fig 5a
Phan L, Chou P, Velazquez Torres G, Samudio I, Parreno K, Huang Y, et al. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nat Commun. 2015;6:7530 pubmed publisher
  • western blot; human; fig 2
Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS ONE. 2015;10:e0132880 pubmed publisher
  • western blot; human
Shao C, Ahmad N, Hodges K, Kuang S, Ratliff T, Liu X. Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer. J Biol Chem. 2015;290:2024-33 pubmed publisher
  • western blot; human; 1:1000
Stefanetti R, Lamon S, Wallace M, Vendelbo M, Russell A, Vissing K. Regulation of ubiquitin proteasome pathway molecular markers in response to endurance and resistance exercise and training. Pflugers Arch. 2015;467:1523-1537 pubmed publisher
  • western blot; mouse
Cao Y, Rathmell J, Macintyre A. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS ONE. 2014;9:e104104 pubmed publisher
  • western blot; human; 1:1000
Stefanetti R, Zacharewicz E, Della Gatta P, Garnham A, Russell A, Lamon S. Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise. Front Physiol. 2014;5:30 pubmed publisher
Yuan S, Qiao T, Zhuang X, Chen W, Xing N, Zhang Q. Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro. Yonsei Med J. 2016;57:1312-23 pubmed publisher
Liu K, Li F, Han H, Chen Y, Mao Z, Luo J, et al. Parkin Regulates the Activity of Pyruvate Kinase M2. J Biol Chem. 2016;291:10307-17 pubmed publisher
Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, et al. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. Nat Med. 2015;21:457-66 pubmed publisher
Metheni M, Echebli N, Chaussepied M, Ransy C, Chereau C, Jensen K, et al. The level of H?O? type oxidative stress regulates virulence of Theileria-transformed leukocytes. Cell Microbiol. 2014;16:269-79 pubmed publisher
Sajic T, Hainard A, Scherl A, Wohlwend A, Negro F, Sanchez J, et al. STAT6 promotes bi-directional modulation of PKM2 in liver and adipose inflammatory cells in rosiglitazone-treated mice. Sci Rep. 2013;3:2350 pubmed publisher
Zhuang Q, Li J, Wu Z, Zhang J, Sun W, Li T, et al. Differential proteome analysis of bone marrow mesenchymal stem cells from adolescent idiopathic scoliosis patients. PLoS ONE. 2011;6:e18834 pubmed publisher
product information
SKU :
3198S
Product-Name :
PKM2 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Frozen)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
60
Host :
Rabbit
Target :
PKM2
Primary-Protein :
PKM2
Alt-Names :
CTHBP,Cytosolic thyroid hormone-binding protein,KPYM,MGC3932,OIP-3,OIP3,Opa-interacting protein 3,PK, muscle type,PK2,PK3,PKM,PKM2,Pyruvate kinase 2/3,Pyruvate kinase isozymes M1/M2,Pyruvate kinase muscle isozyme,TCB,THBP1,Thyroid hormone-binding protein 1,Tumor M2-PK,p58,pyruvate kinase, muscle,thyroid hormone-binding protein, cytosolic
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.