product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
E-Cadherin (24E10) Rabbit mAb
catalog :
3195
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
24E10
reactivity :
human, mouse, dogs, bovine, pigs , rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other, mass cytometry
citations: 470
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2h
Liu Q, Li H, Yang M, Mei Y, Niu T, Zhou Z, et al. Suppression of tumor growth and metastasis in Shkbp1 knockout mice. Cancer Gene Ther. 2022;29:709-721 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Lin G, Li J, Cai J, Zhang H, Xin Q, Wang N, et al. RNA-binding Protein MBNL2 regulates Cancer Cell Metastasis through MiR-182-MBNL2-AKT Pathway. J Cancer. 2021;12:6715-6726 pubmed publisher
  • western blot; mouse; 1:5000; loading ...
Passman A, Strauss R, McSpadden S, Finch Edmondson M, Andrewartha N, Woo K, et al. Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry; mouse; fig 4c
Fu H, Gui Y, Liu S, Wang Y, Bastacky S, Qiao Y, et al. The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment. iScience. 2021;24:103112 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 2c
  • western blot; human; 1:1000; loading ...; fig 2b
Gyamfi J, Yeo J, Kwon D, Min B, Cha Y, Koo J, et al. Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer. NPJ Breast Cancer. 2021;7:129 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a, 5c
Chen R, Sheng C, Ma R, Zhang L, Yang L, Chen Y. PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer. Mol Med Rep. 2021;24: pubmed publisher
  • western blot; human; loading ...; fig 6c, 6f
Sun Z, Sun D, Feng Y, Zhang B, Sun P, Zhou B, et al. Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer. Mol Ther Nucleic Acids. 2021;26:253-268 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3d
  • western blot; human; 1:1000; loading ...; fig 2b
Goel S, Bhatia V, Kundu S, Biswas T, Carskadon S, Gupta N, et al. Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progression. Nat Commun. 2021;12:5325 pubmed publisher
  • western blot; pigs ; 1:1000; loading ...; fig s2d
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, et al. Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration. Virulence. 2021;12:2296-2313 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 1l
Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, et al. Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer. Nat Commun. 2021;12:5196 pubmed publisher
  • western blot; mouse; fig 5b
Gu P, Wang D, Zhang J, Wang X, Chen Z, Gu L, et al. Protective function of interleukin-22 in pulmonary fibrosis. Clin Transl Med. 2021;11:e509 pubmed publisher
  • western blot; human; loading ...; fig 6a, 6b
Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, et al. Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway. Clin Transl Med. 2021;11:e522 pubmed publisher
  • western blot; mouse; loading ...; fig s2g
Tan X, Tong L, Li L, Xu J, Xie S, Ji L, et al. Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nat Commun. 2021;12:4853 pubmed publisher
  • immunohistochemistry; mouse; 1:250; fig 7a
Keil Stietz K, Kennedy C, Sethi S, Valenzuela A, Nunez A, Wang K, et al. In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder. Curr Res Toxicol. 2021;2:1-18 pubmed publisher
  • immunohistochemistry; pigs ; loading ...; fig s4
Bailey K, Cartwright S, Patel N, Remmers N, Lazenby A, Hollingsworth M, et al. Porcine pancreatic ductal epithelial cells transformed with KRASG12D and SV40T are tumorigenic. Sci Rep. 2021;11:13436 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3b
  • western blot; mouse; loading ...; fig 3d
Zhou Y, Ji H, Xu Q, Zhang X, Cao X, Chen Y, et al. Congenital biliary atresia is correlated with disrupted cell junctions and polarity caused by Cdc42 insufficiency in the liver. Theranostics. 2021;11:7262-7275 pubmed publisher
  • western blot; human; loading ...; fig 6d
Cheng X, Wang J, Liu C, Jiang T, Yang N, Liu D, et al. Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway. J Exp Clin Cancer Res. 2021;40:199 pubmed publisher
  • immunohistochemistry; rhesus macaque; 1:1000; fig 4a
Rosenkrantz J, Gaffney J, Roberts V, Carbone L, CHAVEZ S. Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation. BMC Biol. 2021;19:127 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3e
Wu Y, Guo Q, Ju X, Hu Z, Xia L, Deng Y, et al. HNRNPH1-stabilized LINC00662 promotes ovarian cancer progression by activating the GRP78/p38 pathway. Oncogene. 2021;40:4770-4782 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 5e
Yin S, Liu L, Brobbey C, PALANISAMY V, Ball L, Olsen S, et al. PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021;12:3444 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2s
Monsivais D, Nagashima T, Prunskaite Hyyryläinen R, Nozawa K, Shimada K, Tang S, et al. Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis. Nat Commun. 2021;12:3386 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2i
Jiang H, Deng W, Zhu K, Zeng Z, Hu B, Zhou Z, et al. LINC00467 Promotes Prostate Cancer Progression via M2 Macrophage Polarization and the miR-494-3p/STAT3 Axis. Front Oncol. 2021;11:661431 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s10a
Wojnarowicz P, Escolano M, Huang Y, Desai B, Chin Y, Shah R, et al. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021;7:58 pubmed publisher
  • western blot; human; loading ...; fig 3b
Lin C, Tsai M, Chen Y, Liu W, Lin C, Hsu K, et al. Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo. Biomol Ther (Seoul). 2021;29:551-561 pubmed publisher
  • immunohistochemistry; human; loading ...; fig s6b
Eriksen A, Møller R, Makovoz B, Uhl S, tenOever B, Blenkinsop T. SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium. Cell Stem Cell. 2021;28:1205-1220.e7 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
  • western blot; mouse; 1:500; loading ...; fig 4b
Liu M, Rao H, Liu J, Li X, Feng W, Gui L, et al. The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis. Redox Biol. 2021;43:102004 pubmed publisher
  • immunohistochemistry; human; loading ...; fig s5-1e
Hendley A, Rao A, Leonhardt L, Ashe S, Smith J, Giacometti S, et al. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. elife. 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s4a
Liberti D, Kremp M, Liberti W, Penkala I, Li S, Zhou S, et al. Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury. Cell Rep. 2021;35:109092 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig s2l
Fukunaga I, Oe Y, Chen C, Danzaki K, Ohta S, Koike A, et al. Activin/Nodal/TGF-β Pathway Inhibitor Accelerates BMP4-Induced Cochlear Gap Junction Formation During in vitro Differentiation of Embryonic Stem Cells. Front Cell Dev Biol. 2021;9:602197 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:200; fig 4b
  • western blot; human; fig 3a
Delepine C, Pham V, Tsang H, Sur M. GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration. PLoS ONE. 2021;16:e0251173 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4b
Wang X, Li X, Lin F, Sun H, Lin Y, Wang Z, et al. The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis. J Exp Clin Cancer Res. 2021;40:151 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s3b
Carstens J, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews K, et al. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Cell Rep. 2021;35:108990 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3e, 5c
Zhang L, Li M, Tian C, Wang T, Mi S. CCAAT enhancer binding protein α suppresses proliferation, metastasis, and epithelial-mesenchymal transition of ovarian cancer cells via suppressing the Wnt/β-catenin signaling. Neoplasma. 2021;68:602-612 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4c
  • western blot; mouse; 1:1000; loading ...; fig s11b
  • western blot; human; 1:1000; loading ...; fig 4b
Tyagi A, Sharma S, Wu K, Wu S, Xing F, Liu Y, et al. Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung. Nat Commun. 2021;12:474 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Jiang Y, Han Q, Zhao H, Zhang J. Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/β-catenin/c-Myc signaling and reprogramming glycolysis. J Exp Clin Cancer Res. 2021;40:13 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3e
Ye D, Wang S, Huang Y, Wang X, Chi P. USP43 directly regulates ZEB1 protein, mediating proliferation and metastasis of colorectal cancer. J Cancer. 2021;12:404-416 pubmed publisher
  • western blot; human; loading ...; fig 3c
Wang C, Weng M, Xia S, Zhang M, Chen C, Tang J, et al. Distinct roles of programmed death ligand 1 alternative splicing isoforms in colorectal cancer. Cancer Sci. 2021;112:178-193 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher
  • western blot; human; 1:1000; fig 1g
Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6e
Zhu W, Liu C, Lu T, Zhang Y, Zhang S, Chen Q, et al. Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer. Front Oncol. 2020;10:1451 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s1-3a
Aikin T, Peterson A, Pokrass M, Clark H, Regot S. MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s6-2a
Xi L, Carroll T, Matos I, Luo J, Polak L, Pasolli H, et al. m6A RNA methylation impacts fate choices during skin morphogenesis. elife. 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 3e
Huang F, Zheng C, Huang L, Lin C, Wang J. USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer. Cancer Cell Int. 2020;20:346 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3e
Lin Z, Lin X, Zhu L, Huang J, Huang Y. TRIM2 directly deubiquitinates and stabilizes Snail1 protein, mediating proliferation and metastasis of lung adenocarcinoma. Cancer Cell Int. 2020;20:228 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 3h
  • western blot; human; 1:1000; loading ...; fig 3g
Wen X, Wan J, He Q, Wang M, Li S, Jiang M, et al. p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer. Signal Transduct Target Ther. 2020;5:81 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6b, 8b
Wu X, Gardashova G, Lan L, Han S, Zhong C, Marquez R, et al. Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis. Commun Biol. 2020;3:193 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6g
Qi J, Liu S, Liu W, Cai G, Liao G. Identification of UAP1L1 as tumor promotor in gastric cancer through regulation of CDK6. Aging (Albany NY). 2020;12:6904-6927 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1s4a
Matos I, Asare A, Levorse J, Ouspenskaia T, de la Cruz Racelis J, Schuhmacher L, et al. Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development. elife. 2020;9: pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2g
Tian Q, Yuan P, Quan C, Li M, Xiao J, Zhang L, et al. Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer. Oncogene. 2020;39:3980-3996 pubmed publisher
  • western blot; human; loading ...; fig 5i
Alafate W, Li X, Zuo J, Zhang H, Xiang J, Wu W, et al. Elevation of CXCL1 indicates poor prognosis and radioresistance by inducing mesenchymal transition in glioblastoma. CNS Neurosci Ther. 2020;26:475-485 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Guo Y, Zhang Z, Wang Z, Liu G, Liu Y, Wang H. Astragalus polysaccharides inhibit ovarian cancer cell growth via microRNA-27a/FBXW7 signaling pathway. Biosci Rep. 2020;40: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
  • western blot; mouse; 1:500; loading ...; fig 2f
Wang X, Jian X, Dou J, Wei Z, Zhao F. Decreasing Microtubule Actin Cross-Linking Factor 1 Inhibits Melanoma Metastasis by Decreasing Epithelial to Mesenchymal Transition. Cancer Manag Res. 2020;12:663-673 pubmed publisher
  • western blot; human; loading ...; fig 8a
Tian S, Peng P, Li J, Deng H, Zhan N, Zeng Z, et al. SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway. Aging (Albany NY). 2020;12:3574-3593 pubmed publisher
  • western blot; human; loading ...; fig 3c
Zhang Y, Du P, Li Y, Zhu Q, Song X, Liu S, et al. TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. Int J Biol Sci. 2020;16:739-751 pubmed publisher
  • western blot; human; fig 3c
Chandrasekaran B, Dahiya N, Tyagi A, Kolluru V, Saran U, Baby B, et al. Chronic exposure to cadmium induces a malignant transformation of benign prostate epithelial cells. Oncogenesis. 2020;9:23 pubmed publisher
  • western blot; human; loading ...; fig 7d
Liu K, Yu Q, Li H, Xie C, Wu Y, Ma D, et al. BIRC7 promotes epithelial-mesenchymal transition and metastasis in papillary thyroid carcinoma through restraining autophagy. Am J Cancer Res. 2020;10:78-94 pubmed
  • western blot; human; 1:1000; loading ...; fig 2g: 2h, 2i
Li M, Wu P, Yang Z, Deng S, Ni L, Zhang Y, et al. miR-193a-5p promotes pancreatic cancer cell metastasis through SRSF6-mediated alternative splicing of OGDHL and ECM1. Am J Cancer Res. 2020;10:38-59 pubmed
  • western blot; human; loading ...; fig 3f
Guoren Z, Zhaohui F, Wei Z, Mei W, Yuan W, Lin S, et al. TFAP2A Induced ITPKA Serves as an Oncogene and Interacts with DBN1 in Lung Adenocarcinoma. Int J Biol Sci. 2020;16:504-514 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6e
Carpinelli M, de Vries M, Auden A, Butt T, Deng Z, Partridge D, et al. Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure. Dis Model Mech. 2020;13: pubmed publisher
  • western blot; human; loading ...; fig 2f
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R. The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation. Aging (Albany NY). 2020;12:1685-1703 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 3a
  • western blot; mouse; 1:5000; loading ...; fig 3h
Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig s1c
Rahman M, Wruck W, Spitzhorn L, Nguyen L, Bohndorf M, Martins S, et al. The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells. Sci Rep. 2020;10:739 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 4b
Ye D, Zhu J, Zhao Q, Ma W, Xiao Y, Xu G, et al. LMP1 Up-regulates Calreticulin to Induce Epithelial-mesenchymal Transition via TGF-β/Smad3/NRP1 Pathway in Nasopharyngeal Carcinoma Cells. J Cancer. 2020;11:1257-1269 pubmed publisher
  • western blot; human; loading ...; fig 3i
Wang H, Chen Z, Wang S, Gao X, Qian M, Qiu W, et al. TGFβ1-induced beta-site APP-cleaving enzyme 2 upregulation promotes tumorigenesis through the NF-κB signalling pathway in human gliomas. Mol Oncol. 2020;14:407-425 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig s3b
  • immunocytochemistry; human; fig 2g
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2g
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 2i
Cai H, Li J, Zhang Y, Liao Y, Zhu Y, Wang C, et al. LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition. Front Oncol. 2019;9:1446 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5b
Esfahani M, Lee L, Jeon Y, Flynn R, Stehr H, Hui A, et al. Functional significance of U2AF1 S34F mutations in lung adenocarcinomas. Nat Commun. 2019;10:5712 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 2i
  • immunocytochemistry; mouse; 1:200; loading ...; fig 2i
  • western blot; mouse; 1:1000; loading ...; fig 2f
Wu Y, Chen K, Xing G, Li L, Ma B, Hu Z, et al. Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition. Sci Adv. 2019;5:eaax7525 pubmed publisher
  • western blot; human; 1:200; loading ...; fig 3b
Li X, Wang F, Ren M, Du M, Zhou J. The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases. BMC Ophthalmol. 2019;19:219 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s6f
  • western blot; human; 1:1000; loading ...; fig 2d
Lu Y, Zheng Y, Coyaud E, Zhang C, Selvabaskaran A, Yu Y, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019;366:460-467 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1a
Bi J, Yang S, Li L, Dai Q, Borcherding N, Wagner B, et al. Metadherin enhances vulnerability of cancer cells to ferroptosis. Cell Death Dis. 2019;10:682 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5e
  • western blot; human; loading ...; fig 5a
Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M. Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells. BMC Cancer. 2019;19:894 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2c
Padmanaban V, Krol I, Suhail Y, Szczerba B, Aceto N, Bader J, et al. E-cadherin is required for metastasis in multiple models of breast cancer. Nature. 2019;573:439-444 pubmed publisher
  • western blot; human; loading ...; fig 2a
Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
  • western blot; human; loading ...; fig 3d
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, et al. RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer. J Exp Clin Cancer Res. 2019;38:334 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2b
Du F, Qiao C, Li X, Chen Z, Liu H, Wu S, et al. Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR. Theranostics. 2019;9:3879-3902 pubmed publisher
  • western blot; human; loading ...; fig 4i
Fan M, Zou Y, He P, Zhang S, Sun X, Li C. Long non-coding RNA SPRY4-IT1 promotes epithelial-mesenchymal transition of cervical cancer by regulating the miR-101-3p/ZEB1 axis. Biosci Rep. 2019;: pubmed publisher
  • western blot; human; 52 ng/ml; loading ...; fig 5d
Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Singh R, Peng S, Viswanath P, Sambandam V, Shen L, Rao X, et al. Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis. EMBO Mol Med. 2019;: pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 4a
Kim E, Lisby A, Ma C, Lo N, Ehmer U, Hayer K, et al. Promotion of growth factor signaling as a critical function of β-catenin during HCC progression. Nat Commun. 2019;10:1909 pubmed publisher
  • mass cytometry; human; loading ...; fig 3a
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b, 4d
Liu Y, Xue M, Du S, Feng W, Zhang K, Zhang L, et al. Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT. Nat Commun. 2019;10:1637 pubmed publisher
  • western blot; human; fig 5a
Zhang D, Zhou H, Liu J, Mao J. Long Noncoding RNA ASB16-AS1 Promotes Proliferation, Migration, and Invasion in Glioma Cells. Biomed Res Int. 2019;2019:5437531 pubmed publisher
  • western blot; human; loading ...; fig 1f
  • western blot; mouse; loading ...; fig 5f
Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, et al. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019;442:310-319 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4a
  • western blot; mouse; 1:200; loading ...; fig 4c
Ke X, Do D, Li C, Zhao Y, Kollarik M, Fu Q, et al. Ras homolog family member A/Rho-associated protein kinase 1 signaling modulates lineage commitment of mesenchymal stem cells in asthmatic patients through lymphoid enhancer-binding factor 1. J Allergy Clin Immunol. 2019;143:1560-1574.e6 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3c
  • western blot; human; loading ...; fig s1f
Zhu Y, Qu C, Hong X, Jia Y, Lin M, Luo Y, et al. Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1. Cell Death Differ. 2019;26:306-320 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Wang X, Du C, He X, Deng X, He Y, Zhou X. MiR-4463 inhibits the migration of human aortic smooth muscle cells by AMOT. Biosci Rep. 2018;38: pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; loading ...; fig 3b
Vl kov K, Vachtenheim J, R da J, Hor k P, Ondru ov L. Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells. J Cell Mol Med. 2018;22:2240-2251 pubmed publisher
  • western blot; human; 1:1000; fig 1a
Park G, Kim D. Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway. Mol Med Rep. 2018;17:3563-3574 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 6g
El Zowalaty A, Li R, Chen W, Ye X. Seipin deficiency leads to increased endoplasmic reticulum stress and apoptosis in mammary gland alveolar epithelial cells during lactation. Biol Reprod. 2018;98:570-578 pubmed publisher
  • western blot; human; loading ...; fig 3c
Yu R, Longo J, van Leeuwen J, Mullen P, Ba Alawi W, Haibe Kains B, et al. Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins. Cancer Res. 2018;78:1347-1357 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 3a2
Spitzhorn L, Rahman M, Schwindt L, Ho H, Wruck W, Bohndorf M, et al. Isolation and Molecular Characterization of Amniotic Fluid-Derived Mesenchymal Stem Cells Obtained from Caesarean Sections. Stem Cells Int. 2017;2017:5932706 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 3b
Ma Q, Wang Y, Zhang T, Zuo W. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy. Life Sci. 2018;193:104-109 pubmed publisher
  • immunocytochemistry; human; loading ...
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al. A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. Cell Stem Cell. 2017;21:399-410.e7 pubmed publisher
  • western blot; human; loading ...; fig 2j
Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, et al. Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-?B signaling pathway. Mol Cancer. 2017;16:117 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Zhang C, Mao H, Cao Y. Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner. Sci Rep. 2017;7:3769 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 7b
  • immunocytochemistry; human; loading ...; fig 6d
  • western blot; human; fig 6a
Liang X, Yuan X, Yu J, Wu Y, Li K, Sun C, et al. Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes. EBioMedicine. 2017;21:104-116 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1g
Logan C, Rajakaruna S, Bowen C, Radice G, Robinson M, Menko A. N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017;428:118-134 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
  • western blot; human; loading ...; fig s3a-b
Xia L, Huang W, Bellani M, Seidman M, Wu K, Fan D, et al. CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes. Cancer Cell. 2017;31:653-668.e7 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 2a
Giroux V, Lento A, Islam M, Pitarresi J, Kharbanda A, Hamilton K, et al. Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. J Clin Invest. 2017;127:2378-2391 pubmed publisher
  • immunocytochemistry; mouse; 1:250; fig 3c
Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2a
Yan X, Zhu Z, Xu S, Yang L, Liao X, Zheng M, et al. MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways. Sci Rep. 2017;7:45915 pubmed publisher
  • western blot; human; loading ...; fig 5c
Kannan A, Hertweck K, Philley J, Wells R, Dasgupta S. Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer. Sci Rep. 2017;7:46102 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4b
Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7b
Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  • immunocytochemistry; human; 1:100; fig 3b
Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed publisher
  • western blot; human; loading ...; fig 2g
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6d
Li X, Liu W, Chen X, Wang Y, Shi D, Zhang H, et al. Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer. Int J Mol Med. 2017;39:927-935 pubmed publisher
  • western blot; human; loading ...; fig 2c
Chang Y, Lin T, Campbell M, Pan C, Lee S, Lee H, et al. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017;7:42795 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4b
Tao L, Xiang D, Xie Y, Bronson R, Li Z. Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours. Nat Commun. 2017;8:14431 pubmed publisher
  • western blot; human; loading ...; fig s2
Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed publisher
  • western blot; human; loading ...
Zhai S, Liu C, Zhang L, Zhu J, Guo J, Zhang J, et al. PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail. Neoplasia. 2017;19:154-164 pubmed publisher
  • western blot; human; loading ...; fig 3d
Gonzalez M, Martin E, Anwar T, Arellano Garcia C, Medhora N, Lama A, et al. Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth. Cell Rep. 2017;18:1215-1228 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6b
  • western blot; human; loading ...; fig 7a
He Y, Northey J, Pelletier A, Kos Z, Meunier L, Haibe Kains B, et al. The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene. 2017;36:3490-3503 pubmed publisher
  • western blot; human; loading ...; fig 3e
Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, et al. The pattern of hMENA isoforms is regulated by TGF-?1 in pancreatic cancer and may predict patient outcome. Oncoimmunology. 2016;5:e1221556 pubmed publisher
  • western blot; human; loading ...; fig 5a
Xu J, Zhang X, Wang H, Ge S, Gao T, Song L, et al. HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition. Biomed Pharmacother. 2017;88:421-429 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4d
Das S, Jackson W, Prasain J, Hanna A, Bailey S, Tucker J, et al. Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling. Sci Rep. 2017;7:40773 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5c
Zhang Y, An J, Lv W, Lou T, Liu Y, Kang W. miRNA-129-5p suppresses cell proliferation and invasion in lung cancer by targeting microspherule protein 1, E-cadherin and vimentin. Oncol Lett. 2016;12:5163-5169 pubmed publisher
  • western blot; mouse; loading ...; fig 5b
Jiang C, Diao F, Sang Y, Xu N, Zhu R, Wang X, et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet. 2017;13:e1006535 pubmed publisher
  • western blot; human; loading ...; fig 10
Boylan K, Buchanan P, Manion R, Shukla D, Braumberger K, Bruggemeyer C, et al. The expression of Nectin-4 on the surface of ovarian cancer cells alters their ability to adhere, migrate, aggregate, and proliferate. Oncotarget. 2017;8:9717-9738 pubmed publisher
  • immunocytochemistry; human; 1:2000; fig 4b
  • western blot; human; 1:2000; loading ...; fig 1b
Yu J, Lei R, Zhuang X, Li X, Li G, Lev S, et al. MicroRNA-182 targets SMAD7 to potentiate TGF?-induced epithelial-mesenchymal transition and metastasis of cancer cells. Nat Commun. 2016;7:13884 pubmed publisher
  • western blot; human; loading ...; fig 4g
Amoroso M, Matassa D, Agliarulo I, Avolio R, Lu H, Sisinni L, et al. TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial-mesenchymal transition. Cell Death Dis. 2016;7:e2522 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2c
Lloyd Lewis B, Davis F, Harris O, Hitchcock J, Lourenco F, Pasche M, et al. Imaging the mammary gland and mammary tumours in 3D: optical tissue clearing and immunofluorescence methods. Breast Cancer Res. 2016;18:127 pubmed
  • immunohistochemistry; mouse; loading ...; fig 3f
Yuan J, Cha J, Deng W, Bartos A, Sun X, Ho H, et al. Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proc Natl Acad Sci U S A. 2016;113:E8079-E8088 pubmed
  • western blot; human; 1:1000; loading ...; fig 5a
He X, Liu Z, Xia Y, Xu J, Lv G, Wang L, et al. HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs. Oncotarget. 2017;8:1247-1261 pubmed publisher
  • western blot; human; fig 5b
Burgy O, Bellaye P, Causse S, Beltramo G, Wettstein G, Boutanquoi P, et al. Pleural inhibition of the caspase-1/IL-1? pathway diminishes profibrotic lung toxicity of bleomycin. Respir Res. 2016;17:162 pubmed
  • immunocytochemistry; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 5c
Bryson B, Junk D, Cipriano R, Jackson M. STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence. Cell Cycle. 2017;16:319-334 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3e
Chaudhury A, Cheema S, Fachini J, Kongchan N, Lu G, Simon L, et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun. 2016;7:13362 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig s13b
Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016;7:13369 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1c
Davis F, Lloyd Lewis B, Harris O, Kozar S, Winton D, Muresan L, et al. Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny. Nat Commun. 2016;7:13053 pubmed publisher
  • western blot; human; loading ...; fig 6a
Sheets J, Iwanicki M, Liu J, Howitt B, Hirsch M, Gubbels J, et al. SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance. Oncogenesis. 2016;5:e264 pubmed publisher
  • immunohistochemistry; human; 1:200; loading ...; fig 7b
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7a
Cronan M, Beerman R, ROSENBERG A, Saelens J, Johnson M, Oehlers S, et al. Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity. 2016;45:861-876 pubmed publisher
  • western blot; human; fig s1c
Zhao X, Li L, Wang X, Fu R, Lv Y, Jin W, et al. Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0164752 pubmed publisher
  • western blot; mouse; fig s2a
  • immunohistochemistry; human; loading ...; fig 3b
  • western blot; human; loading ...; fig s2a
Shenoy A, Jin Y, Luo H, Tang M, Pampo C, Shao R, et al. Epithelial-to-mesenchymal transition confers pericyte properties on cancer cells. J Clin Invest. 2016;126:4174-4186 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1
  • western blot; human; loading ...; fig 1d
Liu B, Dong H, Lin X, Yang X, Yue X, Yang J, et al. RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion. Oncotarget. 2016;7:82411-82423 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s1b
Little A, Sham D, Hristova M, Danyal K, Heppner D, Bauer R, et al. DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties. Oncogenesis. 2016;5:e261 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2e
  • immunocytochemistry; human; 1:200; loading ...; fig 3e
  • western blot; human; 1:500; loading ...; fig 3d
Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  • western blot; mouse; 1:2000; fig 3d
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, et al. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo. Oncotarget. 2016;7:63730-63746 pubmed publisher
  • immunohistochemistry; human; 1:400; loading ...; fig 2c
Jones R, Robinson T, Liu J, Shrestha M, Voisin V, Ju Y, et al. RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation. J Clin Invest. 2016;126:3739-3757 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 6
Ayres Pereira M, Mandel Clausen T, Pehrson C, Mao Y, Resende M, Daugaard M, et al. Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1. PLoS Pathog. 2016;12:e1005831 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6c
  • western blot; mouse; loading ...; fig 6a
Hong J, Shin M, Douglas I, Chung K, Kim E, Jung J, et al. Inhibition of EphA2/EphrinA1 signal attenuates lipopolysaccharide-induced lung injury. Clin Sci (Lond). 2016;130:1993-2003 pubmed
  • western blot; human; loading ...; fig 2b
Liu L, Phua Y, Lee R, Ma X, Jenkins Y, Novy K, et al. Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. J Biol Chem. 2016;291:21571-21583 pubmed
  • immunohistochemistry; mouse; 1:300; fig 2
Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H. A critical role for NF2 and the Hippo pathway in branching morphogenesis. Nat Commun. 2016;7:12309 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Chiang K, Hsu S, Lin S, Yeh C, Pang J, Wang S, et al. PTEN Insufficiency Increases Breast Cancer Cell Metastasis In Vitro and In Vivo in a Xenograft Zebrafish Model. Anticancer Res. 2016;36:3997-4005 pubmed
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; 1:1000; fig 3
Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2b
Mihajlovic A, Bruce A. Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development. Reprod Biomed Online. 2016;33:381-90 pubmed publisher
  • immunocytochemistry; human; fig 1
Pijuan Galitó S, Tamm C, Schuster J, Sobol M, Forsberg L, Merry C, et al. Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture. Nat Commun. 2016;7:12170 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 2c
Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Yang S, Tsai C, Pan Y, Yeh C, Pang J, Takano M, et al. MART-10, a newly synthesized vitamin D analog, represses metastatic potential of head and neck squamous carcinoma cells. Drug Des Devel Ther. 2016;10:1995-2002 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4a
Zhang Q, Liu S, Parajuli K, Zhang W, Zhang K, Mo Z, et al. Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. Oncogene. 2017;36:687-699 pubmed publisher
  • immunohistochemistry; human; fig s3
Hatem R, El Botty R, Chateau Joubert S, Servely J, Labiod D, de Plater L, et al. Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers. Oncotarget. 2016;7:48206-48219 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 5m
Stock K, Estrada M, Vidic S, Gjerde K, Rudisch A, Santo V, et al. Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery. Sci Rep. 2016;6:28951 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 1b
Xie Y, Lu W, Liu S, Yang Q, Goodwin J, Sathyanarayana S, et al. MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo. Oncotarget. 2016;7:47609-47619 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 2e
Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science. 2016;352:1576-80 pubmed publisher
  • western blot; mouse; 1:500; fig s7
Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016;7:11876 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 1b
Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, et al. Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit. Oncotarget. 2016;7:45414-45428 pubmed publisher
  • western blot; human; 1:1000; fig 1
Toneff M, Sreekumar A, Tinnirello A, Hollander P, Habib S, Li S, et al. The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC Biol. 2016;14:47 pubmed publisher
  • western blot; human; 1:6000; loading ...; fig 1d
Tisza M, Zhao W, Fuentes J, Prijic S, Chen X, Levental I, et al. Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts. Oncotarget. 2016;7:51553-51568 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1d
Li Q, Sodroski C, Lowey B, Schweitzer C, Cha H, Zhang F, et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2016;113:7620-5 pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 8a
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
  • western blot; human; fig 3b
Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/?-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7:42513-42526 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 5b
Chen H, Lorton B, Gupta V, Shechter D. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression. Oncogene. 2017;36:373-386 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 2
Kuang J, Li L, Guo L, Su Y, Wang Y, Xu Y, et al. RNF8 promotes epithelial-mesenchymal transition of breast cancer cells. J Exp Clin Cancer Res. 2016;35:88 pubmed publisher
  • western blot; human; loading ...; fig 3g
Qi J, Li T, Bian H, Li F, Ju Y, Gao S, et al. SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis. FEBS Open Bio. 2016;6:326-37 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 1
  • western blot; mouse; 1:1000; fig 1
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed publisher
  • western blot; human; fig 5
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  • western blot; human; fig 7a
Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
  • immunocytochemistry; human; fig 6e
Kuga T, Sasaki M, Mikami T, Miake Y, Adachi J, Shimizu M, et al. FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes. Sci Rep. 2016;6:26557 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5d
He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; fig 6f
Petit F, Deng C, Jamin S. Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice. Int J Biol Sci. 2016;12:667-76 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig s3
de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
  • western blot; human; loading ...; fig 4a
Yang Y, Lu Y, Wang L, Mizokami A, Keller E, Zhang J, et al. Skp2 is associated with paclitaxel resistance in prostate cancer cells. Oncol Rep. 2016;36:559-66 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 5f
Lee Y, Kim S, Song S, Hong H, Lee Y, Oh B, et al. Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways. Oncotarget. 2016;7:36842-36853 pubmed publisher
  • western blot; human; fig 5
Bie Q, Sun C, Gong A, Li C, Su Z, Zheng D, et al. Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer. Sci Rep. 2016;6:25447 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 3
Rolo A, Savery D, Escuin S, de Castro S, Armer H, Munro P, et al. Regulation of cell protrusions by small GTPases during fusion of the neural folds. elife. 2016;5:e13273 pubmed publisher
  • western blot; human; 1:1000; fig 4
Chiang K, Yeh T, Chen S, Pang J, Yeh C, Hsu J, et al. The Vitamin D Analog, MART-10, Attenuates Triple Negative Breast Cancer Cells Metastatic Potential. Int J Mol Sci. 2016;17: pubmed publisher
  • western blot; human; 1:2000; fig 3
Lin S, Kao C, Lee H, Creighton C, Ittmann M, Tsai S, et al. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016;7:11418 pubmed publisher
  • western blot; human; fig 4
Leung C, Mak W, Kai A, Chan K, Lee T, Ng I, et al. Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/?-catenin signaling. Oncotarget. 2016;7:29371-86 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; tbl 2
Sato K, Suda K, Shimizu S, Sakai K, Mizuuchi H, Tomizawa K, et al. Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. PLoS ONE. 2016;11:e0154186 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 2
Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed publisher
  • western blot; human; 1:1000; fig 5
Wang Z, Xie J, Yan M, Wang J, Wang X, Zhang J, et al. Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma. Oncotarget. 2016;7:26765-79 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400; fig 2
Yu J, Berga S, Johnston MacAnanny E, Sidell N, Bagchi I, Bagchi M, et al. Endometrial Stromal Decidualization Responds Reversibly to Hormone Stimulation and Withdrawal. Endocrinology. 2016;157:2432-46 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 7
Lee N, Fok K, White A, Wilson N, O Leary C, Cox H, et al. Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nat Commun. 2016;7:11082 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
Holloway K, Sinha V, Bu W, Toneff M, Dong J, Peng Y, et al. Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. Int J Biol Sci. 2016;12:381-8 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 3
Vermeer D, Coppock J, Zeng E, Lee K, Spanos W, Onken M, et al. Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis. Oncotarget. 2016;7:24194-207 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 4g
  • western blot; mouse; loading ...; fig 4f
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, et al. Differential TGF? pathway targeting by miR-122 in humans and mice affects liver cancer metastasis. Nat Commun. 2016;7:11012 pubmed publisher
  • western blot; human; fig 1
Schmidt T, Perna A, Fugmann T, Böhm M, Jan Hiss -, Haller S, et al. Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA. Sci Rep. 2016;6:23264 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250; fig 1
Tan S, Krasnow M. Developmental origin of lung macrophage diversity. Development. 2016;143:1318-27 pubmed publisher
  • western blot; human; 1:1000; fig 2
  • western blot; mouse; 1:1000; fig 6
Dhar S, Kumar A, Zhang L, Rimando A, Lage J, Lewin J, et al. Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer. Oncotarget. 2016;7:18469-84 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 1c
  • western blot; human; 1:1000; loading ...; fig s3b
Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed publisher
  • western blot; human; fig 4d
Chang H, Liu Y, Xue M, Liu H, Du S, Zhang L, et al. Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition. Nucleic Acids Res. 2016;44:2514-27 pubmed publisher
  • western blot; human; loading ...; fig 3d
Yang Z, Liu S, Zhu M, Zhang H, Wang J, Xu Q, et al. PS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway. Sci Rep. 2016;6:22090 pubmed publisher
  • western blot; human; loading ...; fig 4b
Matsuda Y, Miura K, Yamane J, Shima H, Fujibuchi W, Ishida K, et al. SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer. Cancer Sci. 2016;107:619-28 pubmed publisher
  • immunocytochemistry; human; fig 4
He Y, Ryu T, Shrestha N, Yuan T, Kim H, Shrestha H, et al. Interaction of EGFR to δ-catenin leads to δ-catenin phosphorylation and enhances EGFR signaling. Sci Rep. 2016;6:21207 pubmed publisher
  • immunocytochemistry; human; fig 6
  • immunohistochemistry; human; fig 4
  • western blot; human; fig 6
Yin G, Liu Z, Wang Y, Dou C, Li C, Yang W, et al. BCORL1 is an independent prognostic marker and contributes to cell migration and invasion in human hepatocellular carcinoma. BMC Cancer. 2016;16:103 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Du L, Chen X, Cao Y, Lu L, Zhang F, Bornstein S, et al. Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling. Oncogene. 2016;35:4641-52 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 2
  • western blot; human; fig 1
Li J, Pan Q, Rowan P, Trotter T, Peker D, Regal K, et al. Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells. Oncotarget. 2016;7:11299-309 pubmed publisher
  • immunohistochemistry; human; 1:75; fig 4c
Guedj N, Vaquero J, Clapéron A, Mergey M, Chrétien Y, Paradis V, et al. Loss of ezrin in human intrahepatic cholangiocarcinoma is associated with ectopic expression of E-cadherin. Histopathology. 2016;69:211-21 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Chen N, Uddin B, Voit R, Schiebel E. Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion. Proc Natl Acad Sci U S A. 2016;113:990-5 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:5000; fig 4
Creedon H, Balderstone L, Muir M, Balla J, Gómez Cuadrado L, Tracey N, et al. Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer. Dis Model Mech. 2016;9:131-40 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 4
Benitz S, Regel I, Reinhard T, Popp A, Schäffer I, Raulefs S, et al. Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells. Oncotarget. 2016;7:11424-33 pubmed publisher
  • immunocytochemistry; human; fig s3
  • western blot; human; fig 6
Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4h
Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher
  • western blot; human; 1:1000; fig 1b
Rafehi S, Ramos Valdes Y, Bertrand M, McGee J, Préfontaine M, Sugimoto A, et al. TGFβ signaling regulates epithelial-mesenchymal plasticity in ovarian cancer ascites-derived spheroids. Endocr Relat Cancer. 2016;23:147-59 pubmed publisher
  • western blot; human; 1:500; fig 4
Fleury H, Communal L, Carmona E, Portelance L, Arcand S, Rahimi K, et al. Novel high-grade serous epithelial ovarian cancer cell lines that reflect the molecular diversity of both the sporadic and hereditary disease. Genes Cancer. 2015;6:378-398 pubmed
  • western blot; human; fig 4
Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 3
Wang G, Yu Y, Sun C, Liu T, Liang T, Zhan L, et al. STAT3 selectively interacts with Smad3 to antagonize TGF-β signalling. Oncogene. 2016;35:4388-98 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 5
  • western blot; human; 1:200; fig 5
Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, et al. miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer. Oncotarget. 2016;7:293-307 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. Nat Med. 2015;21:1364-71 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 6
  • western blot; human; fig 1
Qin W, Li C, Zheng W, Guo Q, Zhang Y, Kang M, et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget. 2015;6:39839-54 pubmed publisher
  • western blot; human; fig 5
Bauer J, Ozden O, Akagi N, Carroll T, Principe D, Staudacher J, et al. Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer. Mol Cancer. 2015;14:182 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig s3c
Dong W, Zhang X, Liu W, Chen Y, Huang J, Austin E, et al. A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia. J Cell Biol. 2015;211:273-86 pubmed publisher
  • western blot; mouse; fig 2b
Jiang Y, Du M, Wu M, Zhu Y, Zhao X, Cao X, et al. Phosphatidic Acid Improves Reprogramming to Pluripotency by Reducing Apoptosis. Stem Cells Dev. 2016;25:43-54 pubmed publisher
  • flow cytometry; human; 1:200; tbl 4
  • immunocytochemistry; human; 1:500; tbl 4
  • western blot; human; 1:1000; tbl 4
Nath A, Li I, Roberts L, Chan C. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma. Sci Rep. 2015;5:14752 pubmed publisher
  • western blot; human; 1:1000; fig 4
Izumi D, Ishimoto T, Miyake K, Sugihara H, Eto K, Sawayama H, et al. CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer. Int J Cancer. 2016;138:1207-19 pubmed publisher
  • western blot; human; 1:1000; fig 3
Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  • western blot; human; fig 3a
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3d
Kuang X, Zhu J, Peng Z, Wang J, Chen Z. Transducin (Beta)-Like 1 X-Linked Receptor 1 Correlates with Clinical Prognosis and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma. Dig Dis Sci. 2016;61:489-500 pubmed publisher
  • western blot; human; loading ...; fig 8
Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher
  • western blot; human; fig 1
Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher
  • western blot; mouse; 1:4000; fig 1
Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed publisher
  • western blot; human; 1:1000; fig 3
Chiang K, Kuo S, Chen C, Ng S, Lin S, Yeh C, et al. MART-10, the vitamin D analog, is a potent drug to inhibit anaplastic thyroid cancer cell metastatic potential. Cancer Lett. 2015;369:76-85 pubmed publisher
  • immunocytochemistry; human
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, et al. The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. Am J Physiol Gastrointest Liver Physiol. 2015;309:G475-90 pubmed publisher
  • western blot; human
Nagahara T, Shiraha H, Sawahara H, Uchida D, Takeuchi Y, Iwamuro M, et al. Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells. Oncol Rep. 2015;34:1169-77 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
Zhao L, Liu S, Che X, Hou K, Ma Y, Li C, et al. Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors. Int J Mol Med. 2015;36:645-52 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; tbl 1
Huang R, Kuay K, Tan T, Asad M, Tang H, Ng A, et al. Functional relevance of a six mesenchymal gene signature in epithelial-mesenchymal transition (EMT) reversal by the triple angiokinase inhibitor, nintedanib (BIBF1120). Oncotarget. 2015;6:22098-113 pubmed
  • western blot; human; fig 1
Li L, Qi L, Liang Z, Song W, Liu Y, Wang Y, et al. Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells. Int J Mol Med. 2015;36:113-22 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 5
Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 6
  • western blot; mouse; 1:1000; fig 6
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  • immunocytochemistry; mouse; 1:400; fig 6
Modepalli V, Hinds L, Sharp J, Lefevre C, Nicholas K. Role of marsupial tammar wallaby milk in lung maturation of pouch young. BMC Dev Biol. 2015;15:16 pubmed publisher
  • western blot; human; 1:500
ORELLANA R, Kato S, Erices R, Bravo M, Gonzalez P, Oliva B, et al. Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells. BMC Cancer. 2015;15:290 pubmed publisher
  • western blot; human; fig 3
Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed publisher
  • immunohistochemistry; human; 1:400; fig 4
  • western blot; human; 1:1000; fig 4
Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ. Cancer Lett. 2015;360:269-79 pubmed publisher
  • western blot; human; fig 3
Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X. Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling. Int J Gynecol Cancer. 2015;25:345-55 pubmed publisher
  • immunohistochemistry; mouse
Kitamura J, Uemura M, Kurozumi M, Sonobe M, Manabe T, Hiai H, et al. Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer. PLoS ONE. 2015;10:e0117986 pubmed publisher
  • western blot; human; fig 5
Liu S, Lee W, Lai D, Wu S, Liu C, Tien H, et al. Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition. Mol Oncol. 2015;9:834-49 pubmed publisher
  • western blot; human; fig 3
Hsiao S, Chen M, Chen C, Chien M, Hua K, Hsiao M, et al. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer. Ann Surg Oncol. 2015;22 Suppl 3:S1556-65 pubmed publisher
  • western blot; human; loading ...; fig 6
Traenkle B, Emele F, Anton R, Poetz O, Haeussler R, Maier J, et al. Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Mol Cell Proteomics. 2015;14:707-23 pubmed publisher
  • western blot; human; fig 4
Gong X, Yi J, Carmon K, Crumbley C, Xiong W, Thomas A, et al. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. 2015;34:4692-701 pubmed publisher
  • flow cytometry; human
Satelli A, Mitra A, Brownlee Z, Xia X, Bellister S, Overman M, et al. Epithelial-mesenchymal transitioned circulating tumor cells capture for detecting tumor progression. Clin Cancer Res. 2015;21:899-906 pubmed publisher
  • western blot; human; fig 5
Xu M, Zhu C, Zhao X, Chen C, Zhang H, Yuan H, et al. Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. Oncotarget. 2015;6:979-94 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3b
Jannasch K, Wegwitz F, Lenfert E, Maenz C, Deppert W, Alves F. Chemotherapy of WAP-T mouse mammary carcinomas aggravates tumor phenotype and enhances tumor cell dissemination. Int J Cancer. 2015;137:25-36 pubmed publisher
  • immunohistochemistry; human; 1:100
Figueira A, Gomes C, de Oliveira J, Vilhena H, Carvalheira J, de Matos A, et al. Aberrant P-cadherin expression is associated to aggressive feline mammary carcinomas. BMC Vet Res. 2014;10:270 pubmed publisher
  • flow cytometry; mouse; 1:50; fig 9
Easter S, Mitchell E, Baxley S, Desmond R, Frost A, Serra R. Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors. PLoS ONE. 2014;9:e113247 pubmed publisher
  • immunocytochemistry; mouse; 1:200
Akgul Y, Word R, Ensign L, Yamaguchi Y, Lydon J, Hanes J, et al. Hyaluronan in cervical epithelia protects against infection-mediated preterm birth. J Clin Invest. 2014;124:5481-9 pubmed publisher
  • immunohistochemistry; human; 1:400; fig 4
Ciamporcero E, Miles K, Adelaiye R, Ramakrishnan S, Shen L, Ku S, et al. Combination strategy targeting VEGF and HGF/c-met in human renal cell carcinoma models. Mol Cancer Ther. 2015;14:101-10 pubmed publisher
  • immunocytochemistry; human; fig 4
Griner N, Young D, Chaudhary P, Mohamed A, Huang W, Chen Y, et al. ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer. Mol Cancer Res. 2015;13:368-79 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Soncini D, Caffa I, Zoppoli G, Cea M, Cagnetta A, Passalacqua M, et al. Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. J Biol Chem. 2014;289:34189-204 pubmed publisher
  • western blot; human; loading ...; fig 4b
Sako Kubota K, Tanaka N, Nagae S, Meng W, Takeichi M. Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions. Mol Biol Cell. 2014;25:3851-60 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed publisher
  • western blot; human
Tang J, Shen L, Yang Q, Zhang C. Overexpression of metadherin mediates metastasis of osteosarcoma by regulating epithelial-mesenchymal transition. Cell Prolif. 2014;47:427-34 pubmed publisher
  • western blot; human
Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Kono K, Tamashiro D, Alarcon V. Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst. Dev Biol. 2014;394:142-55 pubmed publisher
  • western blot; human
Liu J, Ke F, Xu Z, Liu Z, Zhang L, Yan S, et al. CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo. PLoS ONE. 2014;9:e101137 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:600
  • western blot; human; 1:800
Liang W, Hao Z, Han J, Zhu D, Jin Z, Xie W. CAV-1 contributes to bladder cancer progression by inducing epithelial-to-mesenchymal transition. Urol Oncol. 2014;32:855-63 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Kowtharapu B, Stahnke T, Wree A, Guthoff R, Stachs O. Corneal epithelial and neuronal interactions: role in wound healing. Exp Eye Res. 2014;125:53-61 pubmed publisher
  • western blot; human
Lee M, Kim S, Kim B, Won C, Nam S, Kang S, et al. Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation. Biochim Biophys Acta. 2014;1843:2037-54 pubmed publisher
  • western blot; human; fig 5b
Raimondi L, Amodio N, Di Martino M, Altomare E, Leotta M, Caracciolo D, et al. Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity. Oncotarget. 2014;5:3039-54 pubmed
  • western blot; human
Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
  • western blot; human
Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
Chen D, Sun Y, Yuan Y, Han Z, Zhang P, Zhang J, et al. miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion. PLoS Genet. 2014;10:e1004177 pubmed publisher
  • western blot; human
Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, et al. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Br J Cancer. 2014;110:1497-505 pubmed publisher
  • immunocytochemistry; mouse; fig 6h
Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen Zender I, et al. In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells. PLoS ONE. 2014;9:e88071 pubmed publisher
  • western blot; mouse
Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Park J, Morley T, Scherer P. Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours. EMBO Mol Med. 2013;5:935-48 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed publisher
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Marchetti S, Bengalli R, Floris P, Colombo A, Mantecca P. Combustion-derived particles from biomass sources differently promote epithelial-to-mesenchymal transition on A549 cells. Arch Toxicol. 2021;95:1379-1390 pubmed publisher
Seo H, Kim H, Yoon J, Kweon T, Park Y, Kang J, et al. Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. Cell Death Dis. 2020;11:815 pubmed publisher
Ganesh K, Basnet H, Kaygusuz Y, Laughney A, He L, Sharma R, et al. L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nat Cancer. 2020;1:28-45 pubmed publisher
Mara J, Zhou L, Larmore M, Johnson B, Ayiku R, Amargant F, et al. Ovulation and ovarian wound healing are impaired with advanced reproductive age. Aging (Albany NY). 2020;12:9686-9713 pubmed publisher
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product information
SKU :
3195P
Product-Name :
E-Cadherin (24E10) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, (B, Dg, Pg)
Applications :
Flow cytometry
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
135
Host :
Rabbit
Target :
E-Cadherin
Primary-Protein :
CDH1
Alt-Names :
Arc-1,CADH1,CAM 120/80,CD324,CDH1,CDHE,Cadherin-1,E-Cad/CTF1,E-Cad/CTF2,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,LCAM,UVO,Uvomorulin,cadherin 1, E-cadherin (epithelial),cadherin 1, type 1,cadherin 1, type 1, E-cadherin (epithelial),calcium-dependent adhesion protein, epithelial,cell-CAM 120/80
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.