product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PKM1/2 (C103A3) Rabbit mAb
catalog :
3190
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C103A3
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 5f
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  • western blot; human; fig 3
Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Martins A, Sá R, Monteiro M, Barros A, Sousa M, Carvalho R, et al. Ghrelin acts as energy status sensor of male reproduction by modulating Sertoli cells glycolytic metabolism and mitochondrial bioenergetics. Mol Cell Endocrinol. 2016;434:199-209 pubmed publisher
  • western blot; human; 1:1000; fig s11
Aviner R, Shenoy A, Elroy Stein O, Geiger T. Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis. PLoS Genet. 2015;11:e1005554 pubmed publisher
  • western blot; human; 1:1500; fig 4e
Iansante V, Choy P, Fung S, Liu Y, Chai J, Dyson J, et al. PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nat Commun. 2015;6:7882 pubmed publisher
  • western blot; mouse; fig 2d
Liu X, Haines J, Mehanna E, Genet M, Ben Sahra I, Asara J, et al. ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis. Genes Dev. 2014;28:1917-28 pubmed publisher
Bulusu V, Prior N, Snaebjornsson M, Kuehne A, Sonnen K, Kress J, et al. Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017;40:331-341.e4 pubmed publisher
product information
SKU :
3190S
Product-Name :
PKM1/2 (C103A3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
PKM1/2
Primary-Protein :
PKM2
Alt-Names :
CTHBP,Cytosolic thyroid hormone-binding protein,KPYM,MGC3932,OIP-3,OIP3,Opa-interacting protein 3,PK, muscle type,PK2,PK3,PKM,PKM2,Pyruvate kinase 2/3,Pyruvate kinase isozymes M1/M2,Pyruvate kinase muscle isozyme,TCB,THBP1,Thyroid hormone-binding protein 1,Tumor M2-PK,p58,pyruvate kinase, muscle,thyroid hormone-binding protein, cytosolic
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.