Fatty Acid Synthase (C20G5) Rabbit mAb | Cell Signaling Technology 3180S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Fatty Acid Synthase (C20G5) Rabbit mAb

catalog :

3180S

quantity :

100 ul

price :

235 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, cow

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Dilution	Reference
western blot; mouse; fig 3	Hinds T, Burns K, Hosick P, McBeth L, Nestor-Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α. J Biol Chem. 2016;291:25179-25191 pubmed
western blot; mouse; 1:1000; fig 4	Thomas A, Belaidi E, Aron-Wisnewsky J, van der Zon G, Levy P, Clement K, et al. Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. Sci Rep. 2016;6:24618 pubmed publisher
immunohistochemistry; mouse; 1:100; fig 3d	Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed publisher
western blot; mouse; 1:1000; fig 4	Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen P, Viero G, et al. eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription. Nat Commun. 2015;6:8261 pubmed publisher
western blot; mouse	Shimizu H, Astapova I, Ye F, Bilban M, Cohen R, Hollenberg A. NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Mol Cell Biol. 2015;35:555-65 pubmed publisher
western blot; mouse	Mottillo E, Balasubramanian P, Lee Y, Weng C, Kershaw E, Granneman J. Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation. J Lipid Res. 2014;55:2276-86 pubmed publisher
western blot; human; 1:1000	Liu J, Zheng L, Wu N, Ma L, Zhong J, Liu G, et al. Oleanolic acid induces metabolic adaptation in cancer cells by activating the AMP-activated protein kinase pathway. J Agric Food Chem. 2014;62:5528-37 pubmed publisher
western blot; human	Daniëls V, Smans K, Royaux I, Chypre M, Swinnen J, Zaidi N. Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment. PLoS ONE. 2014;9:e106913 pubmed publisher
western blot; mouse; 1:1000; fig s10e	Lanaspa M, Ishimoto T, Li N, Cicerchi C, Orlicky D, Ruzycki P, et al. Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. Nat Commun. 2013;4:2434 pubmed publisher
immunohistochemistry - paraffin section; mouse western blot; mouse	Antony N, Weir J, McDougall A, Mantamadiotis T, Meikle P, Cole T, et al. cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS ONE. 2013;8:e59763 pubmed publisher
	Duan J, Sun L, Huang H, Wu Z, Wang L, Liao W. Overexpression of fatty acid synthase predicts a poor prognosis for human gastric cancer. Mol Med Rep. 2016;13:3027-35 pubmed publisher
	Tamrakar P, Ibrahim B, Gujar A, Briski K. Estrogen regulates energy metabolic pathway and upstream adenosine 5'-monophosphate-activated protein kinase and phosphatase enzyme expression in dorsal vagal complex metabolosensory neurons during glucostasis and hypoglycemia. J Neurosci Res. 2015;93:321-32 pubmed publisher
	Vyas D, Moallem U, Teter B, Fardin-Kia A, Erdman R. Milk fat responses to butterfat infusion during conjugated linoleic acid-induced milk fat depression in lactating dairy cows. J Dairy Sci. 2013;96:2387-99 pubmed publisher
	Zaytseva Y, Rychahou P, Gulhati P, Elliott V, Mustain W, O'Connor K, et al. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012;72:1504-17 pubmed publisher
	Zhu X, Qin X, Fei M, Hou W, Greshock J, Bachman K, et al. Combined phosphatase and tensin homolog (PTEN) loss and fatty acid synthase (FAS) overexpression worsens the prognosis of Chinese patients with hepatocellular carcinoma. Int J Mol Sci. 2012;13:9980-91 pubmed publisher
	Tiano J, Delghingaro-Augusto V, Le May C, Liu S, Kaw M, Khuder S, et al. Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes. J Clin Invest. 2011;121:3331-42 pubmed publisher
	Okuda T, Morita N. A very low carbohydrate ketogenic diet prevents the progression of hepatic steatosis caused by hyperglycemia in a juvenile obese mouse model. Nutr Diabetes. 2012;2:e50 pubmed
	Hou W, Fei M, Qin X, Zhu X, Greshock J, Liu P, et al. High overexpression of fatty acid synthase is associated with poor survival in Chinese patients with gastric carcinoma. Exp Ther Med. 2012;4:999-1004 pubmed

product information

SKU :

3180S

Product-Name :

Fatty Acid Synthase (C20G5) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, (B)

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Metabolism

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

273

Host :

Rabbit

Target :

FASN

Primary-Protein :

FASN

Alt-Names :

3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase,3-oxoacyl-[acyl-carrier-protein] reductase,3-oxoacyl-[acyl-carrier-protein] synthase,Enoyl-[acyl-carrier-protein] reductase,FAS,FASN,Fatty acid synthase,MGC14367,MGC15706,OA-519,Oleoyl-[acyl-carrier-protein] hydrolase,SDR27X1,[Acyl-carrier-protein] S-acetyltransferase,[Acyl-carrier-protein] S-malonyltransferase,short chain dehydrogenase/reductase family 27X, member 1

more info or order :

Cell Signaling Technology product webpage