product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cathepsin B (D1C7Y) XP Rabbit mAb
catalog :
31718
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1C7Y
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5a
Han X, Li B, Bao J, Wu Z, Chen C, Ni J, et al. Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation. Front Immunol. 2022;13:968639 pubmed publisher
  • western blot; mouse; 1:100; loading ...; fig 5a
Singh N, Das B, Zhou J, Hu X, Yan R. Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance. Sci Adv. 2022;8:eabo3610 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7h
Seike T, Boontem P, Yanagi M, Li S, Kido H, Yamamiya D, et al. Hydroxynonenal Causes Hepatocyte Death by Disrupting Lysosomal Integrity in Nonalcoholic Steatohepatitis. Cell Mol Gastroenterol Hepatol. 2022;14:925-944 pubmed publisher
  • western blot; mouse; loading ...; fig 6f
Eninger T, M xfc ller S, Bacioglu M, Schweighauser M, Lambert M, Maia L, et al. Signatures of glial activity can be detected in the CSF proteome. Proc Natl Acad Sci U S A. 2022;119:e2119804119 pubmed publisher
  • western blot; mouse; 1:10; loading ...; fig 2a, s3a
Shyam R, Ogando D, Choi M, Liton P, Bonanno J. Mitochondrial ROS Induced Lysosomal Dysfunction and Autophagy Impairment in an Animal Model of Congenital Hereditary Endothelial Dystrophy. Invest Ophthalmol Vis Sci. 2021;62:15 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4e
Shen S, Li B, Dai J, Wu Z, He Y, Wen L, et al. BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux. Front Pharmacol. 2020;11:618 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2b
  • immunocytochemistry; human; 1:200; loading ...; fig 4c
Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, et al. Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway. Cell Death Dis. 2018;9:946 pubmed publisher
  • western blot; human; fig 4d
Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher
Nakatsuka A, Yamaguchi S, Eguchi J, Kakuta S, Iwakura Y, Sugiyama H, et al. A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease. Commun Biol. 2021;4:373 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.