product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PDGF Receptor β (28E1) Rabbit mAb
catalog :
3169S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 18
Published Application/Species/DilutionReference
  • western blot; mouse; 1:500; fig 7
Yao Y, Norris E, E Mason C, Strickland S. Laminin regulates PDGFRβ(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Rodda L, Bannard O, Ludewig B, Nagasawa T, Cyster J. Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells. J Immunol. 2015;195:4781-91 pubmed publisher
  • immunohistochemistry; human; 1:50
Swager S, Delfin D, Rastogi N, Wang H, Canan B, Fedorov V, et al. Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1. Cardiovasc Pathol. 2015;24:160-7 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, et al. Proximity-dependent initiation of hybridization chain reaction. Nat Commun. 2015;6:7294 pubmed publisher
  • western blot; human
Jayaprakash P, Dong H, Zou M, Bhatia A, O'Brien K, Chen M, et al. Hsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing. J Cell Sci. 2015;128:1475-80 pubmed publisher
  • western blot; mouse; fig 1a
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, et al. Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. J Biol Chem. 2015;290:9738-52 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Matsushita T, Lankford K, Arroyo E, Sasaki M, Neyazi M, Radtke C, et al. Diffuse and persistent blood-spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells. Exp Neurol. 2015;267:152-64 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
  • western blot; rat
Buschmann I, Hackbusch D, Gatzke N, Dülsner A, Trappiel M, Dagnell M, et al. Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats. J Mol Med (Berl). 2014;92:983-94 pubmed publisher
  • flow cytometry; human; 1:200
  • immunocytochemistry; human; 1:200
Karow M, Schichor C, Beckervordersandforth R, Berninger B. Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014;: pubmed
  • western blot; mouse; 1:500; fig  2
Yao Y, Chen Z, Norris E, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014;5:3413 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:50
Fretz J, Nelson T, Velazquez H, Xi Y, Moeckel G, Horowitz M. Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney Int. 2014;85:1091-102 pubmed publisher
Ohsaka A, Hirota-Komatsu S, Araki M, Komatsu N. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. Biochem Biophys Res Commun. 2015;459:443-9 pubmed publisher
Friedman A, Amzallag A, Pruteanu-Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed publisher
Berghoff A, Birner P, Streubel B, Kenner L, Preusser M. ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC. APMIS. 2014;122:867-72 pubmed publisher
Sánchez-Contreras M, Baker M, Finch N, Nicholson A, Wojtas A, Wszolek Z, et al. Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology. Hum Mutat. 2014;35:964-71 pubmed publisher
Hua Y, Dolence J, Ramanan S, Ren J, Nair S. Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. Mol Nutr Food Res. 2013;57:1611-8 pubmed publisher
Craig J, Mikhailenko I, Noyes N, Migliorini M, Strickland D. The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events. PLoS ONE. 2013;8:e70432 pubmed publisher
Chen J, Ortmeier S, Savinova O, Nareddy V, Beyer A, Wang D, et al. Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway. J Cell Mol Med. 2012;16:2726-35 pubmed publisher
product information
SKU :
3169S
Product-Name :
PDGF Receptor β (28E1) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
190
Host :
Rabbit
Target :
PDGFR-b
Primary-Protein :
PDGFRb
Alt-Names :
Beta-type platelet-derived growth factor receptor,CD140 antigen-like family member B,CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1,PDGFRB,PGFRB,platelet-derived growth factor receptor, beta polypeptide
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.