| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 6b
| Bownes L, Williams A, Marayati R, Quinn C, Hutchins S, Stewart J, et al. Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Knockout Decreases the Malignant Phenotype in Neuroblastoma Cell Lines. Cancers (Basel). 2021;13: pubmed publisher |
- western blot; human; loading ...; fig 2c
| Ostriker A, Xie Y, Chakraborty R, Sizer A, Bai Y, Ding M, et al. TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy. Circulation. 2021;144:455-470 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 4a
| Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. elife. 2021;10: pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 4a
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- western blot; mouse; 1:1000; loading ...; fig 2f
| Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 1f
| Ruscetti M, Morris J, Mezzadra R, Russell J, Leibold J, Romesser P, et al. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell. 2020;181:424-441.e21 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1a
- immunohistochemistry; mouse; 1:200; loading ...; fig 5a
- western blot; mouse; 1:1000; loading ...; fig 5d
| Durrant C, Ruscher K, Sheppard O, Coleman M, Ozen I. Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling. Cell Death Dis. 2020;11:98 pubmed publisher |
- immunocytochemistry; human; fig 1c
| Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed publisher |
- immunocytochemistry; human; 1:300; loading ...; fig 2c
| Karow M, Camp J, Falk S, Gerber T, Pataskar A, Gac Santel M, et al. Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nat Neurosci. 2018;21:932-940 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s2b
| Chung M, Bujnis M, Barkauskas C, Kobayashi Y, Hogan B. Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development. 2018;145: pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4b
| Strell C, Norberg K, Mezheyeuski A, Schnittert J, Kuninty P, Moro C, et al. Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC. Br J Cancer. 2017;117:65-77 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 8b
| Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed publisher |
- immunocytochemistry; human; 1:500; tbl 1
- western blot; human; 1:1000; tbl 1
| Jansson D, Scotter E, Rustenhoven J, Coppieters N, Smyth L, Oldfield R, et al. Interferon-? blocks signalling through PDGFR? in human brain pericytes. J Neuroinflammation. 2016;13:249 pubmed |
- western blot; human; 1:1000; fig 2
| Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3f
| Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed |
- immunocytochemistry; human; 1:200; fig 1
| Sobrino A, Phan D, Datta R, Wang X, Hachey S, Romero López M, et al. 3D microtumors in vitro supported by perfused vascular networks. Sci Rep. 2016;6:31589 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 8
- western blot; mouse; fig 8
- immunohistochemistry - paraffin section; human; fig 7
- western blot; human; fig 7
| Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher |
- western blot; mouse; 1:500; fig 7
| Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 2g
| Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig se1a
- western blot; mouse; loading ...; fig 1f
| Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Rodda L, Bannard O, Ludewig B, Nagasawa T, Cyster J. Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells. J Immunol. 2015;195:4781-91 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig s1n
- flow cytometry; mouse; fig s1t
| Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, et al. Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015;142:2653-64 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 4
| Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, et al. Proximity-dependent initiation of hybridization chain reaction. Nat Commun. 2015;6:7294 pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:200
| Matsushita T, Lankford K, Arroyo E, Sasaki M, Neyazi M, Radtke C, et al. Diffuse and persistent blood-spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells. Exp Neurol. 2015;267:152-64 pubmed publisher |
| Jayaprakash P, Dong H, Zou M, Bhatia A, O Brien K, Chen M, et al. Hsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing. J Cell Sci. 2015;128:1475-80 pubmed publisher |
- western blot; mouse; fig 1a
| Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, et al. Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. J Biol Chem. 2015;290:9738-52 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; tbl 1
| Crncec I, Pathria P, Svinka J, Eferl R. Induction of colorectal cancer in mice and histomorphometric evaluation of tumors. Methods Mol Biol. 2015;1267:145-64 pubmed publisher |
- immunohistochemistry; human; 1:50
| Swager S, DelfÃn D, Rastogi N, Wang H, Canan B, Fedorov V, et al. Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1. Cardiovasc Pathol. 2015;24:160-167 pubmed publisher |
- immunohistochemistry; mouse; fig 3
| Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed publisher |
- western blot; human; 1:1000; fig s6
| Lu H, Clauser K, Tam W, Fröse J, Ye X, Eaton E, et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2014;16:1105-17 pubmed publisher |
- flow cytometry; human; 1:200
- immunocytochemistry; human; 1:200
| Karow M, Schichor C, Beckervordersandforth R, Berninger B. Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014;: pubmed publisher |
- immunohistochemistry - paraffin section; rat; 1:100
- western blot; rat
| Buschmann I, Hackbusch D, Gatzke N, Dülsner A, Trappiel M, Dagnell M, et al. Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats. J Mol Med (Berl). 2014;92:983-94 pubmed publisher |
- western blot; mouse; 1:500; fig 2
| Yao Y, Chen Z, Norris E, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014;5:3413 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:50
| Fretz J, Nelson T, Velazquez H, Xi Y, Moeckel G, Horowitz M. Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney Int. 2014;85:1091-102 pubmed publisher |
| Shibahara T, Ago T, Nakamura K, Tachibana M, Yoshikawa Y, Komori M, et al. Pericyte-Mediated Tissue Repair through PDGFRβ Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke. Eneuro. 2020;7: pubmed publisher |
| Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, et al. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. elife. 2017;6: pubmed publisher |
| Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed publisher |
| Fischer A, Mühlhäuser W, Warscheid B, Radziwill G. Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling. Sci Adv. 2017;3:e1700475 pubmed publisher |
| Andreone B, Chow B, Tata A, Lacoste B, Ben Zvi A, Bullock K, et al. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron. 2017;94:581-594.e5 pubmed publisher |
| Hijmans R, Rasmussen D, Yazdani S, Navis G, van Goor H, Karsdal M, et al. Urinary collagen degradation products as early markers of progressive renal fibrosis. J Transl Med. 2017;15:63 pubmed publisher |
| Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed publisher |
| Nordby Y, Richardsen E, Rakaee M, Ness N, Donnem T, Patel H, et al. High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence. Sci Rep. 2017;7:43378 pubmed publisher |
| Frödin M, Mezheyeuski A, Corvigno S, Harmenberg U, Sandstrom P, Egevad L, et al. Perivascular PDGFR-? is an independent marker for prognosis in renal cell carcinoma. Br J Cancer. 2017;116:195-201 pubmed publisher |
| Mochida S, Hida Y, Tanifuji S, Hagiwara A, Hamada S, Abe M, et al. SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression. Cell Rep. 2016;16:2901-2913 pubmed publisher |
| Poosti F, Bansal R, Yazdani S, Prakash J, Beljaars L, van den Born J, et al. Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice. Oncotarget. 2016;7:54240-54252 pubmed publisher |
| Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed publisher |
| Corvigno S, Wisman G, Mezheyeuski A, van der Zee A, Nijman H, Avall Lundqvist E, et al. Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival. Oncotarget. 2016;7:18573-84 pubmed publisher |
| Friedman A, Amzallag A, Pruteanu Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed publisher |
| Peyre M, Salaud C, Clermont Taranchon E, Niwa Kawakita M, Goutagny S, Mawrin C, et al. PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 2015;6:32713-22 pubmed publisher |
| Ohsaka A, Hirota Komatsu S, Araki M, Komatsu N. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. Biochem Biophys Res Commun. 2015;459:443-9 pubmed publisher |
| Xi Y, Chen M, Liu X, Lu Z, Ding Y, Li D. CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration. Onco Targets Ther. 2014;7:1215-21 pubmed publisher |
| Sánchez Contreras M, Baker M, Finch N, Nicholson A, Wojtas A, Wszolek Z, et al. Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology. Hum Mutat. 2014;35:964-71 pubmed publisher |
| Berghoff A, Birner P, Streubel B, Kenner L, Preusser M. ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC. APMIS. 2014;122:867-72 pubmed publisher |
| Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, et al. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling. PLoS ONE. 2014;9:e92273 pubmed publisher |
| Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, et al. Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE. 2014;9:e84072 pubmed publisher |
| Nair D, Miller K, Lourenssen S, Blennerhassett M. Inflammatory cytokines promote growth of intestinal smooth muscle cells by induced expression of PDGF-R?. J Cell Mol Med. 2014;18:444-54 pubmed publisher |
| Mederacke I, Hsu C, Troeger J, Huebener P, Mu X, Dapito D, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun. 2013;4:2823 pubmed publisher |
| Craig J, Mikhailenko I, Noyes N, Migliorini M, Strickland D. The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events. PLoS ONE. 2013;8:e70432 pubmed publisher |
| Hua Y, Dolence J, Ramanan S, Ren J, Nair S. Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. Mol Nutr Food Res. 2013;57:1611-8 pubmed publisher |
| Helmy K, Halliday J, Fomchenko E, Setty M, Pitter K, Hafemeister C, et al. Identification of global alteration of translational regulation in glioma in vivo. PLoS ONE. 2012;7:e46965 pubmed publisher |
| Wehler T, Hamdi S, Maderer A, Graf C, Gockel I, Schmidtmann I, et al. Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy. Int J Colorectal Dis. 2013;28:385-98 pubmed publisher |
| Chen J, Ortmeier S, Savinova O, Nareddy V, Beyer A, Wang D, et al. Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway. J Cell Mol Med. 2012;16:2726-35 pubmed publisher |
| Weibrecht I, Grundberg I, Nilsson M, Söderberg O. Simultaneous visualization of both signaling cascade activity and end-point gene expression in single cells. PLoS ONE. 2011;6:e20148 pubmed publisher |
| Nazarenko I, Hedrén A, Sjodin H, Orrego A, Andrae J, Afink G, et al. Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells. PLoS ONE. 2011;6:e18303 pubmed publisher |
| Hägglöf C, Hammarsten P, Josefsson A, Stattin P, Paulsson J, Bergh A, et al. Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival. PLoS ONE. 2010;5:e10747 pubmed publisher |
