product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
cGAS
catalog :
31659S
clonality :
monoclonal
conjugate :
nonconjugated
clone name :
D3O8O
reactivity :
mouse
application :
western blot, immunocytochemistry, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 3d
  • immunocytochemistry; mouse; loading ...; fig 3a
Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3e
  • western blot; mouse; loading ...; fig s1f
Barnett K, Coronas Serna J, Zhou W, Ernandes M, Cao A, Kranzusch P, et al. Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019;: pubmed publisher
Wang Y, Fu Z, Li X, Liang Y, Pei S, Hao S, et al. Cytoplasmic DNA sensing by KU complex in aged CD4+ T cell potentiates T cell activation and aging-related autoimmune inflammation. Immunity. 2021;54:632-647.e9 pubmed publisher
Gentili M, Lahaye X, Nadalin F, Nader G, Puig Lombardi E, Hervé S, et al. The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus. Cell Rep. 2019;26:2377-2393.e13 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.