product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PDGF Receptor α Antibody
catalog :
3164
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s2
HERRING B, Hoggatt A, Gupta A, Wo J. Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans, and loss of FOXF1 and FOXF2 results in gastroparesis in mice. Neurogastroenterol Motil. 2018;:e13528 pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig s3d
Real R, Peter M, Trabalza A, Khan S, Smith M, Dopp J, et al. In vivo modeling of human neuron dynamics and Down syndrome. Science. 2018;362: pubmed publisher
  • immunoprecipitation; human; loading ...; fig 1
  • western blot; human; loading ...; fig 3c
Ibata M, Iwasaki J, Fujioka Y, Nakagawa K, Darmanin S, Onozawa M, et al. Leukemogenic kinase FIP1L1-PDGFRA and a small ubiquitin-like modifier E3 ligase, PIAS1, form a positive cross-talk through their enzymatic activities. Cancer Sci. 2017;108:200-207 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Seki T, Hosaka K, Lim S, Fischer C, Honek J, Yang Y, et al. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat. Nat Commun. 2016;7:12152 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4
  • western blot; mouse; fig 4
Morena D, Maestro N, Bersani F, Forni P, Lingua M, Foglizzo V, et al. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. elife. 2016;5: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Fredriksson L, Stevenson T, Su E, Ragsdale M, Moore S, Craciun S, et al. Identification of a neurovascular signaling pathway regulating seizures in mice. Ann Clin Transl Neurol. 2015;2:722-38 pubmed publisher
  • western blot; human; 1:2000; fig st8
Hayashi Y, Bardsley M, Toyomasu Y, Milosavljevic S, Gajdos G, Choi K, et al. Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1. Gastroenterology. 2015;149:420-32.e16 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 3
Giera S, Deng Y, Luo R, Ackerman S, Mogha A, Monk K, et al. The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121 pubmed publisher
Lewandowski S, Nilsson I, Fredriksson L, Lönnerberg P, Muhl L, Zeitelhofer M, et al. Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration. Acta Neuropathol. 2016;131:453-64 pubmed publisher
Findlay J, Hamilton D, Ashford M. BACE1 activity impairs neuronal glucose oxidation: rescue by beta-hydroxybutyrate and lipoic acid. Front Cell Neurosci. 2015;9:382 pubmed publisher
Jansson S, Bendahl P, Grabau D, Falck A, Fernö M, Aaltonen K, et al. The three receptor tyrosine kinases c-KIT, VEGFR2 and PDGFR?, closely spaced at 4q12, show increased protein expression in triple-negative breast cancer. PLoS ONE. 2014;9:e102176 pubmed publisher
Kikuchi K, Hettmer S, Aslam M, Michalek J, Laub W, Wilky B, et al. Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. PLoS Genet. 2014;10:e1004107 pubmed publisher
Fusar Poli E, Zalfa C, D Avanzo F, Tomanin R, Carlessi L, Bossi M, et al. Murine neural stem cells model Hunter disease in vitro: glial cell-mediated neurodegeneration as a possible mechanism involved. Cell Death Dis. 2013;4:e906 pubmed publisher
Klink B, Miletic H, Stieber D, Huszthy P, Campos Valenzuela J, Valenzuela J, et al. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. PLoS ONE. 2013;8:e59773 pubmed publisher
Roswall P, Pietras K. Of mice and men: a comparative study of cancer-associated fibroblasts in mammary carcinoma. Ups J Med Sci. 2012;117:196-201 pubmed publisher
Nazarenko I, Hedrén A, Sjodin H, Orrego A, Andrae J, Afink G, et al. Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells. PLoS ONE. 2011;6:e18303 pubmed publisher
Corbo V, Beghelli S, Bersani S, Antonello D, Talamini G, Brunelli M, et al. Pancreatic endocrine tumours: mutational and immunohistochemical survey of protein kinases reveals alterations in targetable kinases in cancer cell lines and rare primaries. Ann Oncol. 2012;23:127-34 pubmed publisher
Shao M, Rossi S, Chelladurai B, Shimizu M, Ntukogu O, Ivan M, et al. PDGF induced microRNA alterations in cancer cells. Nucleic Acids Res. 2011;39:4035-47 pubmed publisher
product information
SKU :
3164S
Product-Name :
PDGF Receptor α Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
195
Host :
Rabbit
Target :
PDGFR-a
Primary-Protein :
PDGFRa
Alt-Names :
Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140A,CD140a antigen,MGC74795,PDGF-R-alpha,PDGFR2,PDGFRA,PGFRA,RHEPDGFRA,platelet-derived growth factor receptor, alpha polypeptide,rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.