| Published Application/Species/Dilution | Reference |
|---|
- chromatin immunoprecipitation; human; fig 4
- western blot (knockdown validation); human; fig 4
| Pacini L, Savini C, Ghittoni R, Saidj D, Lamartine J, Hasan U, et al. Downregulation of Toll-Like Receptor 9 Expression by Beta Human Papillomavirus 38 and Implications for Cell Cycle Control. J Virol. 2015;89:11396-405 pubmed publisher |
- western blot; human; fig 3
| Zhang Q, Wan M, Shi J, Horita D, Miller L, Kute T, et al. Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation. J Mol Cell Biol. 2016;: pubmed |
- western blot; mouse; 1:1000; fig 3
| Wurm S, Zhang J, Guinea-Viniegra J, Garcia F, Munoz J, Bakiri L, et al. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev. 2015;29:144-56 pubmed publisher |
- immunoprecipitation; human
| Negishi M, Wongpalee S, Sarkar S, Park J, Lee K, Shibata Y, et al. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. PLoS ONE. 2014;9:e95216 pubmed publisher |
- western blot; human; fig 1
| Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50
| Piper M, Barry G, Harvey T, McLeay R, Smith A, Harris L, et al. NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci. 2014;34:2921-30 pubmed publisher |
| Lee S, Phipson B, Hyland C, Leong H, Allan R, Lun A, et al. Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma. Blood. 2013;122:2654-63 pubmed publisher |
- immunocytochemistry; human
- immunohistochemistry; mouse
- western blot; human
| Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Res. 2013;73:4559-70 pubmed publisher |
- immunocytochemistry; human
| Martin N, Popov N, Aguilo F, O'Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation. EMBO J. 2013;32:982-95 pubmed publisher |
| Chen H, Gao S, Li J, Liu D, Sheng C, Yao C, et al. Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer. Oncotarget. 2015;6:13049-59 pubmed |
| Oravecz A, Apostolov A, Polak K, Jost B, Le Gras S, Chan S, et al. Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2. Nat Commun. 2015;6:8823 pubmed publisher |
| Matsuda Y, Kobayashi-Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M. Epigenetic heterogeneity in HIV-1 latency establishment. Sci Rep. 2015;5:7701 pubmed publisher |
| Ding X, Wang X, Sontag S, Qin J, Wanek P, Lin Q, et al. The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation. Stem Cells Dev. 2014;23:931-40 pubmed publisher |
| Atta H, El-Rehany M, Hammam O, Abdel-Ghany H, Ramzy M, Roderfeld M, et al. Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS ONE. 2014;9:e112384 pubmed publisher |
| Baas R, Lelieveld D, van Teeffelen H, Lijnzaad P, Castelijns B, van Schaik F, et al. A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels. J Biomol Screen. 2014;19:287-96 pubmed publisher |
| Riquelme E, Suraokar M, Behrens C, Lin H, Girard L, Nilsson M, et al. VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy. Clin Cancer Res. 2014;20:3849-61 pubmed publisher |
| Nakashima Y, Haneji T. Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss. PLoS ONE. 2013;8:e72033 pubmed publisher |
| Niegisch G, Knievel J, Koch A, Hader C, Fischer U, Albers P, et al. Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers. Urol Oncol. 2013;31:1770-9 pubmed publisher |
| Saurat N, Andersson T, Vasistha N, Molnar Z, Livesey F. Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Dev. 2013;8:14 pubmed publisher |
| Stovall D, Wan M, Miller L, Cao P, Maglic D, Zhang Q, et al. The regulation of SOX7 and its tumor suppressive role in breast cancer. Am J Pathol. 2013;183:1645-53 pubmed publisher |
| Kalushkova A, Fryknäs M, Lemaire M, Fristedt C, Agarwal P, Eriksson M, et al. Polycomb target genes are silenced in multiple myeloma. PLoS ONE. 2010;5:e11483 pubmed publisher |
| Esposito F, Tornincasa M, Pallante P, Federico A, Borbone E, Pierantoni G, et al. Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2. J Clin Endocrinol Metab. 2012;97:E710-8 pubmed publisher |
| Van Dessel N, Beke L, Görnemann J, Minnebo N, Beullens M, Tanuma N, et al. The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets. Nucleic Acids Res. 2010;38:7500-12 pubmed publisher |
| Wan M, Huang W, Kute T, Miller L, Zhang Q, Hatcher H, et al. Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27. Am J Pathol. 2012;180:2120-33 pubmed publisher |
