product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CDK6 (DCS83) Mouse mAb
catalog :
3136S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
DCS83

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot
citations: 11
Published Application/Species/DilutionReference
  • western blot; mouse; fig 1
Lagarrigue S, López-Mejía I, Denechaud P, Escote X, Castillo-Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed publisher
  • western blot; human; fig 4
Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
  • western blot; human
van der Linden M, Willekes M, van Roon E, Seslija L, Schneider P, Pieters R, et al. MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. Cell Cycle. 2014;13:834-44 pubmed publisher
  • western blot; human; 1:500
Malaviya A, Sylvester P. Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146 pubmed publisher
Zhang K, Dai L, Zhang B, Xu X, Shi J, Fu L, et al. miR-203 is a direct transcriptional target of E2F1 and causes G1 arrest in esophageal cancer cells. J Cell Physiol. 2015;230:903-10 pubmed publisher
Wu Y, Crawford M, Mao Y, Lee R, Davis I, Elton T, et al. Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer. Mol Ther Nucleic Acids. 2013;2:e84 pubmed publisher
Nakles R, Kallakury B, Furth P. The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. Am J Pathol. 2013;182:1976-85 pubmed publisher
Chang S, Chang C, Lee D, Lee P, Yeh Y, Yeh C, et al. Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad. Proc Natl Acad Sci U S A. 2008;105:3927-32 pubmed publisher
Huang X, Schwind S, Yu B, Santhanam R, Wang H, Hoellerbauer P, et al. Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia. Clin Cancer Res. 2013;19:2355-67 pubmed publisher
Cabrera M, Diaz-Cruz E, Kallakury B, Pishvaian M, Grubbs C, Muccio D, et al. The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway. Cancer Prev Res (Phila). 2012;5:810-21 pubmed publisher
Kaneko M, Matsuda D, Ohtawa M, Fukuda T, Nagamitsu T, Yamori T, et al. Potentiation of bleomycin in Jurkat cells by fungal pycnidione. Biol Pharm Bull. 2012;35:18-28 pubmed
product information
SKU :
3136S
Product-Name :
CDK6 (DCS83) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
36
Host :
Mouse
Target :
Cdk6
Primary-Protein :
CDK6
Alt-Names :
CDK6,Cell division protein kinase 6,MGC59692,PLSTIRE,Serine/threonine-protein kinase PLSTIRE,cyclin-dependent kinase 6
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.