Smad2 (86F7) Rabbit mAb | Cell Signaling Technology 3122S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Smad2 (86F7) Rabbit mAb

catalog :

3122S

quantity :

100 ul

price :

235 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Dilution	Reference
western blot; human; 1:1000; fig 2b immunoprecipitation; human; 1:1000; fig 2.d,e	Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher
western blot; human; fig 7	Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie P, et al. Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells. J Biol Chem. 2015;290:20105-16 pubmed publisher
immunocytochemistry; human; 1:300; fig 7	Zoppi N, Chiarelli N, Cinquina V, Ritelli M, Colombi M. GLUT10 deficiency leads to oxidative stress and non-canonical αvβ3 integrin-mediated TGFβ signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts. Hum Mol Genet. 2015;24:6769-87 pubmed publisher
western blot; human; 1:1000	Lee J, Fricke F, Warnken U, Schnolzer M, Kopitz J, Gebert J. Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells. PLoS ONE. 2015;10:e0131506 pubmed publisher
western blot; human; 1:1000	Yu Y, Xiao C, Tan L, Wang Q, Li X, Feng Y. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling. Br J Cancer. 2014;110:724-32 pubmed publisher
	Krishnan S, Szabo E, Burghardt I, Frei K, Tabatabai G, Weller M. Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition. Oncotarget. 2015;6:22480-95 pubmed
	Wu Y, Chang T, Huang Y, Huang H, Chou C. COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer. Oncogene. 2014;33:3432-40 pubmed publisher
	Roth P, Silginer M, Goodman S, Hasenbach K, Thies S, Maurer G, et al. Integrin control of the transforming growth factor-β pathway in glioblastoma. Brain. 2013;136:564-76 pubmed publisher
	Xie W, Aisner S, Baredes S, Sreepada G, Shah R, Reiss M. Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma. Head Neck. 2013;35:76-85 pubmed publisher
	Manser C, Guillot F, Vagnoni A, Davies J, Lau K, McLoughlin D, et al. Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo. Oncogene. 2012;31:2773-82 pubmed publisher
	Louafi F, Martinez-Nunez R, Sanchez-Elsner T. MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem. 2010;285:41328-36 pubmed publisher

product information

SKU :

3122S

Product-Name :

Smad2 (86F7) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Developmental Biology

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

Smad2

Primary-Protein :

Smad2

Alt-Names :

JV18,JV18-1,MAD homolog 2,MAD, mothers against decapentaplegic homolog 2,MADH2,MADR2,MGC22139,MGC34440,Mad protein homolog,Mad-related protein 2,Mothers against DPP homolog 2,Mothers against decapentaplegic homolog 2,SMAD 2,SMAD family member 2,SMAD, mothers against DPP homolog 2,SMAD2,Sma- and Mad-related protein 2,hMAD-2,hSMAD2,mother against DPP homolog 2

more info or order :

Cell Signaling Technology product webpage