Published Application/Species/Sample/Dilution | Reference |
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- immunocytochemistry; dogs; 1:2000; loading ...; fig 5a
- western blot; dogs; 1:2000; loading ...; fig 5c
| Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, et al. Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci Adv. 2020;6:eaay9819 pubmed publisher
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- western blot; human; loading ...; fig 2f
| Dufton N, Peghaire C, Osuna Almagro L, Raimondi C, Kalna V, Chuahan A, et al. Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis. Nat Commun. 2017;8:895 pubmed publisher
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- western blot; human; loading ...; fig 1e
| Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher
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- western blot; human; fig 6d
| Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 2c
| Griggs L, Hassan N, Malik R, Griffin B, Martinez B, Elmore L, et al. Fibronectin fibrils regulate TGF-?1-induced Epithelial-Mesenchymal Transition. Matrix Biol. 2017;60-61:157-175 pubmed publisher
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- western blot; human; loading ...; fig s2d
| Sun J, Liu X, Gao H, Zhang L, Ji Q, Wang Z, et al. Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis. Oncotarget. 2017;8:11489-11506 pubmed publisher
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- western blot; human; 1:1000; fig 1
| Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher
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- western blot; human; fig 3
| Sato N, Takasaka N, Yoshida M, Tsubouchi K, Minagawa S, Araya J, et al. Metformin attenuates lung fibrosis development via NOX4 suppression. Respir Res. 2016;17:107 pubmed publisher
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- western blot; human; loading ...; fig 2k
| Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed publisher
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- western blot; human; fig 4
| Dai Y, Wang L, Tang J, Cao P, Luo Z, Sun J, et al. Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress. Oncotarget. 2016;7:25478-92 pubmed publisher
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- western blot; human; fig 1
| Micha D, Voermans E, Eekhoff M, van Essen H, Zandieh Doulabi B, Netelenbos C, et al. Inhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease. Bone. 2016;84:169-180 pubmed publisher
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- western blot; human; 1:1000; fig s1a
| Rafehi S, Ramos Valdes Y, Bertrand M, McGee J, Préfontaine M, Sugimoto A, et al. TGFβ signaling regulates epithelial-mesenchymal plasticity in ovarian cancer ascites-derived spheroids. Endocr Relat Cancer. 2016;23:147-59 pubmed publisher
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- western blot; human; 1:1000; fig 5
| Buczek M, Miles A, Green W, Johnson C, Boocock D, Pockley A, et al. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. Oncogene. 2016;35:3465-75 pubmed publisher
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- immunocytochemistry; human; 1:300; fig 7
| Zoppi N, Chiarelli N, Cinquina V, Ritelli M, Colombi M. GLUT10 deficiency leads to oxidative stress and non-canonical αvβ3 integrin-mediated TGFβ signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts. Hum Mol Genet. 2015;24:6769-87 pubmed publisher
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- western blot; human; fig 4c
| Marchiq I, Albrengues J, Granja S, Gaggioli C, Pouysségur J, Simon M. Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction. Oncotarget. 2015;6:24636-48 pubmed publisher
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- western blot; human; fig 7
| Huygens C, Liénart S, Dedobbeleer O, Stockis J, Gauthy E, Coulie P, et al. Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells. J Biol Chem. 2015;290:20105-16 pubmed publisher
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- western blot; human; 1:1000
| Lee J, Fricke F, Warnken U, Schnölzer M, Kopitz J, Gebert J. Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells. PLoS ONE. 2015;10:e0131506 pubmed publisher
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- western blot; human; 1:1000; fig s1
| Krishnan S, Szabo E, Burghardt I, Frei K, Tabatabai G, Weller M. Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition. Oncotarget. 2015;6:22480-95 pubmed
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- immunoprecipitation; human; 1:1000; fig 2.d,e
- western blot; human; 1:1000; fig 2b
| Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher
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- western blot; human; 1:1000
| Yu Y, Xiao C, Tan L, Wang Q, Li X, Feng Y. Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-? signalling. Br J Cancer. 2014;110:724-32 pubmed publisher
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| Cheng J, Qin B, Liu B, Huang T, Li Y, Ma L. Maternal embryonic leucine zipper kinase inhibits epithelial-mesenchymal transition by regulating transforming growth factor-? signaling. Oncol Lett. 2017;13:4794-4798 pubmed publisher
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| Alves M, Figuerêdo R, Azevedo F, Cavallaro D, Neto N, Lima J, et al. Adipose tissue fibrosis in human cancer cachexia: the role of TGF? pathway. BMC Cancer. 2017;17:190 pubmed publisher
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| Chen P, Qin L, Li G, Tellides G, Simons M. Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression. EMBO Mol Med. 2016;8:712-28 pubmed publisher
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| Cekanaviciute E, Fathali N, Doyle K, Williams A, Han J, Buckwalter M. Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice. Glia. 2014;62:1227-40 pubmed publisher
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| Wu Y, Chang T, Huang Y, Huang H, Chou C. COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer. Oncogene. 2014;33:3432-40 pubmed publisher
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| Han G, Bian L, Li F, Cotrim A, Wang D, Lu J, et al. Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis. Nat Med. 2013;19:421-8 pubmed publisher
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| Roth P, Silginer M, Goodman S, Hasenbach K, Thies S, Maurer G, et al. Integrin control of the transforming growth factor-? pathway in glioblastoma. Brain. 2013;136:564-76 pubmed publisher
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| McKean D, Niswander L. Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1:874-83 pubmed publisher
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| Cherukuri P, DeCastro A, Balboni A, Downey S, Liu J, Hutchinson J, et al. Phosphorylation of ?Np63? via a novel TGF?/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGF?. PLoS ONE. 2012;7:e50066 pubmed publisher
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| Xie W, Aisner S, Baredes S, Sreepada G, Shah R, Reiss M. Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma. Head Neck. 2013;35:76-85 pubmed publisher
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| Manser C, Guillot F, Vagnoni A, Davies J, Lau K, McLoughlin D, et al. Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo. Oncogene. 2012;31:2773-82 pubmed publisher
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| Zode G, Sethi A, Brun Zinkernagel A, Chang I, Clark A, Wordinger R. Transforming growth factor-?2 increases extracellular matrix proteins in optic nerve head cells via activation of the Smad signaling pathway. Mol Vis. 2011;17:1745-58 pubmed
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| Zi Z, Feng Z, Chapnick D, Dahl M, Deng D, Klipp E, et al. Quantitative analysis of transient and sustained transforming growth factor-? signaling dynamics. Mol Syst Biol. 2011;7:492 pubmed publisher
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| Ng K, Lee Y, Lai W, Chan Y, Fung M, Tse H, et al. Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells. PLoS ONE. 2011;6:e19787 pubmed publisher
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| Dogar A, Towbin H, Hall J. Suppression of latent transforming growth factor (TGF)-beta1 restores growth inhibitory TGF-beta signaling through microRNAs. J Biol Chem. 2011;286:16447-58 pubmed publisher
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| Louafi F, Martinez Nunez R, Sanchez Elsner T. MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem. 2010;285:41328-36 pubmed publisher
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| Polyakova V, Miyagawa S, Szalay Z, Risteli J, Kostin S. Atrial extracellular matrix remodelling in patients with atrial fibrillation. J Cell Mol Med. 2008;12:189-208 pubmed publisher
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