product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Smad2/3 Antibody
catalog :
3102
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, zebrafish
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4a
Sun W, Byon C, Kim D, Choi H, Park J, Joo S, et al. Renoprotective Effects of Maslinic Acid on Experimental Renal Fibrosis in Unilateral Ureteral Obstruction Model via Targeting MyD88. Front Pharmacol. 2021;12:708575 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Gyamfi J, Yeo J, Kwon D, Min B, Cha Y, Koo J, et al. Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancer. NPJ Breast Cancer. 2021;7:129 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6b
Escasany E, Lanzón B, García Carrasco A, Izquierdo Lahuerta A, Torres L, Corrales P, et al. Transforming growth factor β3 deficiency promotes defective lipid metabolism and fibrosis in murine kidney. Dis Model Mech. 2021;14: pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Kiepas A, Voorand E, Senecal J, Ahn R, Annis M, Jacquet K, et al. The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation. J Biol Chem. 2020;: pubmed publisher
  • western blot; zebrafish ; loading ...; fig 2h
Yan Y, Ning G, Li L, Liu J, Yang S, Cao Y, et al. The BMP ligand Pinhead together with Admp supports the robustness of embryonic patterning. Sci Adv. 2019;5:eaau6455 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Deng Q, Li P, Che M, Liu J, Biswas S, Ma G, et al. Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin. elife. 2019;8: pubmed publisher
  • western blot; mouse; loading ...; fig 3c
Seki M, Furukawa N, Koitabashi N, Obokata M, Conway S, Arakawa H, et al. Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension. PLoS ONE. 2019;14:e0220795 pubmed publisher
  • western blot; human; loading ...; fig 1b
Liu Z, Li C, Kang N, Malhi H, Shah V, Maiers J. Transforming growth factor β (TGFβ) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation. J Biol Chem. 2019;294:3137-3151 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6d
Wang L, Chai Y, Li C, Liu H, Su W, Liu X, et al. Oxidized phospholipids are ligands for LRP6. Bone Res. 2018;6:22 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3b
Mönnich M, Borgeskov L, Breslin L, Jakobsen L, Rogowski M, Doğanlı C, et al. CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium. Cell Rep. 2018;22:2584-2592 pubmed publisher
  • western blot; mouse; loading ...; fig 6a
Han W, Li X, Zhang H, Yu B, Guo C, Deng C. Recombinant human elafin promotes alveologenesis in newborn mice exposed to chronic hyperoxia. Int J Biochem Cell Biol. 2017;92:173-182 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; zebrafish ; 1:1000; fig 3
  • western blot; human; 1:1000; fig 5
Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q. Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun. 2016;7:12603 pubmed publisher
  • western blot; human; fig 1
Languino L, Singh A, Prisco M, Inman G, Luginbuhl A, Curry J, et al. Exosome-mediated transfer from the tumor microenvironment increases TGF? signaling in squamous cell carcinoma. Am J Transl Res. 2016;8:2432-7 pubmed
  • western blot; human; 1:1000; loading ...; fig s5
Zuckerwise L, Li J, Lu L, Men Y, Geng T, Buhimschi C, et al. H19 long noncoding RNA alters trophoblast cell migration and invasion by regulating TβR3 in placentae with fetal growth restriction. Oncotarget. 2016;7:38398-38407 pubmed publisher
  • western blot; mouse; fig 6
Illich D, Zhang M, Ursu A, Osorno R, Kim K, Yoon J, et al. Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs. Cell Rep. 2016;15:787-800 pubmed publisher
  • western blot; human; 1:1000; fig 4
Bassey Archibong B, Kwiecien J, Milosavljevic S, Hallett R, Rayner L, Erb M, et al. Kaiso depletion attenuates transforming growth factor-? signaling and metastatic activity of triple-negative breast cancer cells. Oncogenesis. 2016;5:e208 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig s4
  • western blot; mouse; 1:500; fig 6
Thakur A, Nigri J, Lac S, Leca J, Bressy C, Berthezene P, et al. TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma. Cell Death Differ. 2016;23:1358-70 pubmed publisher
Lee E, Boldo L, Fernandez B, Feelisch M, Harmsen M. Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1. Sci Rep. 2017;7:42487 pubmed publisher
Wang C, Kemp Harper B, Kocan M, Ang S, Hewitson T, Samuel C. The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor, Diethylamine NONOate. Front Pharmacol. 2016;7:91 pubmed publisher
Kimura T, Nojiri T, Hino J, Hosoda H, Miura K, Shintani Y, et al. C-type natriuretic peptide ameliorates pulmonary fibrosis by acting on lung fibroblasts in mice. Respir Res. 2016;17:19 pubmed publisher
product information
SKU :
3102S
Product-Name :
Smad2/3 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
52, 60
Host :
Rabbit
Target :
Smad2/Smad3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.