product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-ROS1 (Tyr2274) Antibody
catalog :
3078
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; scFv; fig 3
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Drilon A, Somwar R, Wagner J, Vellore N, Eide C, Zabriskie M, et al. A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer. Clin Cancer Res. 2016;22:2351-8 pubmed publisher
  • western blot; human; 1:1000
Davare M, Vellore N, Wagner J, Eide C, Goodman J, Drilon A, et al. Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors. Proc Natl Acad Sci U S A. 2015;112:E5381-90 pubmed publisher
product information
SKU :
3078L
Product-Name :
Phospho-ROS1 (Tyr2274) Antibody
Size :
300 ul
Price-(USD) :
658 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
258
Host :
Rabbit
Target :
Ros (Tyr2274) phosphate
Primary-Protein :
ROS
Alt-Names :
MCF3,Proto-oncogene tyrosine-protein kinase ROS,ROS,ROS1,c-ros oncogene 1 , receptor tyrosine kinase,c-ros-1,proto-oncogene c-ros-1 protein,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.