product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Met (Tyr1234/1235) (D26) XP® Rabbit mAb
catalog :
3077S
quantity :
100 ul
price :
301 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; human
  • western blot; human
Navis A, van Lith S, van Duijnhoven S, de Pooter M, Yetkin-Arik B, Wesseling P, et al. Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein. Acta Neuropathol. 2015;130:131-44 pubmed publisher
  • western blot; mouse; fig s3
Etnyre D, Stone A, Fong J, Jacobs R, Uppada S, Botting G, et al. Targeting c-Met in melanoma: mechanism of resistance and efficacy of novel combinatorial inhibitor therapy. Cancer Biol Ther. 2014;15:1129-41 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Elliott V, Rychahou P, Zaytseva Y, Evers B. Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model. PLoS ONE. 2014;9:e97432 pubmed publisher
  • western blot; human
Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
Chu C, Bottaro D, Betenbaugh M, Shiloach J. Stable Ectopic Expression of ST6GALNAC5 Induces Autocrine MET Activation and Anchorage-Independence in MDCK Cells. PLoS ONE. 2016;11:e0148075 pubmed publisher
Webster M, Fan C. c-MET regulates myoblast motility and myocyte fusion during adult skeletal muscle regeneration. PLoS ONE. 2013;8:e81757 pubmed publisher
Benedettini E, Sholl L, Peyton M, Reilly J, Ware C, Davis L, et al. Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis. Am J Pathol. 2010;177:415-23 pubmed publisher
Straussman R, Morikawa T, Shee K, Barzily-Rokni M, Qian Z, Du J, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature. 2012;487:500-4 pubmed publisher
product information
SKU :
3077S
Product-Name :
Phospho-Met (Tyr1234/1235) (D26) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
301 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
145
Host :
Rabbit
Target :
Met (Tyr1234/Tyr1235) phosphate
Primary-Protein :
Met
Alt-Names :
AUTS9,HGF receptor,HGF/SF receptor,HGFR,Hepatocyte growth factor receptor,MET,Proto-oncogene c-Met,RCCP2,SF receptor,Scatter factor receptor,Tyrosine-protein kinase Met,c-Met,met proto-oncogene (hepatocyte growth factor receptor),met proto-oncogene tyrosine kinase,oncogene MET
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.