product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-c-Kit (Tyr703) (D12E12) Rabbit mAb
catalog :
3073
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D12E12
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 4e
Hemming M, Lawlor M, Zeid R, Lesluyes T, Fletcher J, Raut C, et al. Gastrointestinal stromal tumor enhancers support a transcription factor network predictive of clinical outcome. Proc Natl Acad Sci U S A. 2018;115:E5746-E5755 pubmed publisher
  • western blot; human; loading ...; fig 1e
Zhan Y, Guo J, Yang W, Goncalves C, Rzymski T, Dreas A, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. J Clin Invest. 2017;127:4179-4192 pubmed publisher
  • western blot; human; fig 4
Nakayama R, Zhang Y, Czaplinski J, Anatone A, Sicinska E, Fletcher J, et al. Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. Oncotarget. 2016;7:16581-92 pubmed publisher
  • western blot; human; 1:500; fig 1
Vajravelu B, Hong K, Al Maqtari T, Cao P, Keith M, Wysoczynski M, et al. C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways. PLoS ONE. 2015;10:e0140798 pubmed publisher
  • western blot; human
Ainsua Enrich E, Serrano Candelas E, Álvarez Errico D, Picado C, Sayós J, Rivera J, et al. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. J Immunol. 2015;194:4309-18 pubmed publisher
Huang F, Shao W, Fujinaga K, Peterlin B. Bromodomain-containing protein 4-independent transcriptional activation by autoimmune regulator (AIRE) and NF-κB. J Biol Chem. 2018;293:4993-5004 pubmed publisher
König H, Coughlan K, Kinsella S, Breen B, Prehn J. The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes. Neurobiol Dis. 2014;70:99-107 pubmed publisher
Kathawala R, Sodani K, Chen K, Patel A, Abuznait A, Anreddy N, et al. Masitinib antagonizes ATP-binding cassette subfamily C member 10-mediated paclitaxel resistance: a preclinical study. Mol Cancer Ther. 2014;13:714-23 pubmed publisher
product information
SKU :
3073S
Product-Name :
Phospho-c-Kit (Tyr703) (D12E12) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
145
Host :
Rabbit
Target :
Kit (Tyr703) phosphate
Primary-Protein :
Kit
Alt-Names :
C-Kit,CD117,KIT,Mast/stem cell growth factor receptor,PBT,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit,proto-oncogene tyrosine-protein kinase Kit,soluble KIT variant 1,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.