product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Akt2 (D6G4) Rabbit mAb
catalog :
3063P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 12
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; fig 6d
Ramlee M, Yan T, Cheung A, Chuah C, Li S. High-throughput genotyping of CRISPR/Cas9-mediated mutants using fluorescent PCR-capillary gel electrophoresis. Sci Rep. 2015;5:15587 pubmed publisher
  • western blot; rat; fig 6
de Castro Barbosa T, Ingerslev L, Alm P, Versteyhe S, Massart J, Rasmussen M, et al. High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring. Mol Metab. 2016;5:184-97 pubmed publisher
  • western blot; mouse; fig 3
Møller C, Kjøbsted R, Enriori P, Jensen T, Garcia-Rudaz C, Litwak S, et al. α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK. PLoS ONE. 2016;11:e0157027 pubmed publisher
  • western blot; human; fig 6
Albers P, Bojsen-Møller K, Dirksen C, Serup A, Kristensen D, Frystyk J, et al. Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol. 2015;309:R510-24 pubmed publisher
  • western blot; human; 1:1000
Hellesøy M, Lorens J. Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis. Mol Biol Cell. 2015;26:2698-711 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
  • western blot; mouse; 1:1000; fig s9
Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  • western blot; human
Andersen T, Schmidt J, Thomassen M, Hornstrup T, Frandsen U, Randers M, et al. A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports. 2014;24:43-56 pubmed publisher
  • western blot; rat
Domingues N, Pelletier J, Ostenson C, Castro M. Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats. J Inorg Biochem. 2014;131:115-22 pubmed publisher
Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed
Tsen F, Bhatia A, O'Brien K, Cheng C, Chen M, Hay N, et al. Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol Cell Biol. 2013;33:4947-59 pubmed publisher
Mijouin L, Rosselin M, Bottreau E, Pizarro-Cerda J, Cossart P, Velge P, et al. Salmonella enteritidis Rck-mediated invasion requires activation of Rac1, which is dependent on the class I PI 3-kinases-Akt signaling pathway. FASEB J. 2012;26:1569-81 pubmed publisher
product information
SKU :
3063P
Product-Name :
Akt2 (D6G4) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Akt2
Primary-Protein :
Akt2
Alt-Names :
AKT2,Murine thymoma viral (v-akt) homolog-2,PKB beta,PKBB,PKBBETA,PRKBB,Protein kinase Akt-2,Protein kinase B beta,RAC-BETA,RAC-PK-beta,RAC-beta serine/threonine-protein kinase,rac protein kinase beta,v-akt murine thymoma viral oncogene homolog 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.