| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; loading ...; fig 1a
| Wang J, Zhao W, Guo H, Fang Y, Stockman S, Bai S, et al. AKT isoform-specific expression and activation across cancer lineages. BMC Cancer. 2018;18:742 pubmed publisher |
- western blot; mouse; loading ...; fig 4b
| Protack C, Foster T, Hashimoto T, Yamamoto K, Lee M, Kraehling J, et al. Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency. Sci Rep. 2017;7:15386 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig 4a
- western blot; human; 1:1000; loading ...; fig 4c
| Weng Y, Shi Y, Xia X, Zhou W, Wang H, Wang C. A multi-shRNA vector enhances the silencing efficiency of exogenous and endogenous genes in human cells. Oncol Lett. 2017;13:1553-1562 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Nonomiya Y, Noguchi K, Tanaka N, Kasagaki T, Katayama K, Sugimoto Y. Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells. Cancer Sci. 2016;107:1877-1887 pubmed publisher |
- western blot; mouse; fig 3
| Møller C, Kjøbsted R, Enriori P, Jensen T, Garcia Rudaz C, Litwak S, et al. ?-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK. PLoS ONE. 2016;11:e0157027 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Shriver M, Marimuthu S, Paul C, Geist J, Seale T, Konstantopoulos K, et al. Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit. Oncotarget. 2016;7:45414-45428 pubmed publisher |
- western blot; human; loading ...; fig 6a
| Li X, Dai X, Wan L, Inuzuka H, Sun L, North B. Smurf1 regulation of DAB2IP controls cell proliferation and migration. Oncotarget. 2016;7:26057-69 pubmed publisher |
| de Castro Barbosa T, Ingerslev L, Alm P, Versteyhe S, Massart J, Rasmussen M, et al. High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring. Mol Metab. 2016;5:184-197 pubmed publisher |
- western blot; human; fig 3
| Andersen T, Schmidt J, Pedersen M, Krustrup P, Bangsbo J. The Effects of 52 Weeks of Soccer or Resistance Training on Body Composition and Muscle Function in +65-Year-Old Healthy Males--A Randomized Controlled Trial. PLoS ONE. 2016;11:e0148236 pubmed publisher |
- western blot; human; fig 5f
| Ramlee M, Yan T, Cheung A, Chuah C, Li S. High-throughput genotyping of CRISPR/Cas9-mediated mutants using fluorescent PCR-capillary gel electrophoresis. Sci Rep. 2015;5:15587 pubmed publisher |
- western blot; mouse; 1:1000; fig s9
| Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher |
- western blot; human; fig 6
| Albers P, Bojsen Møller K, Dirksen C, Serup A, Kristensen D, Frystyk J, et al. Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery. Am J Physiol Regul Integr Comp Physiol. 2015;309:R510-24 pubmed publisher |
- western blot; human; 1:1000
| Hellesøy M, Lorens J. Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis. Mol Biol Cell. 2015;26:2698-711 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher |
| Bisson J, Mills B, Paul Helt J, Zwaka T, Cohen E. Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT. Dev Biol. 2015;398:80-96 pubmed publisher |
| Andersen T, Schmidt J, Thomassen M, Hornstrup T, Frandsen U, Randers M, et al. A preliminary study: effects of football training on glucose control, body composition, and performance in men with type 2 diabetes. Scand J Med Sci Sports. 2014;24 Suppl 1:43-56 pubmed publisher |
| Elliott V, Rychahou P, Zaytseva Y, Evers B. Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model. PLoS ONE. 2014;9:e97432 pubmed publisher |
| Domingues N, Pelletier J, Ostenson C, Castro M. Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats. J Inorg Biochem. 2014;131:115-22 pubmed publisher |
- western blot; human; 1:1000
| Iacovides D, Johnson A, Wang N, Boddapati S, Korkola J, Gray J. Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay. Mol Cell Proteomics. 2013;12:3210-20 pubmed publisher |
| Yoo B, Khan I, Koomson A, Gowda P, Sasazuki T, Shirasawa S, et al. Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells. Autophagy. 2018;14:134-151 pubmed publisher |
| Riggio M, Perrone M, Polo M, Rodríguez M, May M, Abba M, et al. AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins. Sci Rep. 2017;7:44244 pubmed publisher |
| Yang S, Zhao X, Xu H, Chen F, Xu Y, Li Z, et al. AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia. Int J Mol Sci. 2017;18: pubmed publisher |
| Zhang Z, Rankin S, Zorn A. Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development. Dev Biol. 2016;416:187-199 pubmed publisher |
| Li Z, Yang Z, Passaniti A, Lapidus R, Liu X, Cullen K, et al. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation. Oncotarget. 2016;7:31892-906 pubmed publisher |
| Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed |
| Tsen F, Bhatia A, O Brien K, Cheng C, Chen M, Hay N, et al. Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol Cell Biol. 2013;33:4947-59 pubmed publisher |
| Mijouin L, Rosselin M, Bottreau E, Pizarro Cerda J, Cossart P, Velge P, et al. Salmonella enteritidis Rck-mediated invasion requires activation of Rac1, which is dependent on the class I PI 3-kinases-Akt signaling pathway. FASEB J. 2012;26:1569-81 pubmed publisher |
