product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LKB1 (27D10) Rabbit mAb
catalog :
3050S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
clone name :
27D10

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 3
Sundararaman A, Amirtham U, Rangarajan A. Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation. J Biol Chem. 2016;291:14410-29 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Iglesias-Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Li J, Liu J, Li P, Mao X, Li W, Yang J, et al. Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion. J Exp Clin Cancer Res. 2014;33:70 pubmed publisher
  • western blot; human; 1:1000
Bouchekioua-Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed publisher
Wei C, Bhattaram V, Igwe J, Fleming E, Tirnauer J. The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells. PLoS ONE. 2012;7:e41118 pubmed publisher
Nakada Y, Stewart T, Peña C, Zhang S, Zhao N, Bardeesy N, et al. The LKB1 tumor suppressor as a biomarker in mouse and human tissues. PLoS ONE. 2013;8:e73449 pubmed publisher
Vu V, Bui P, Eguchi M, Xu A, Sweeney G. Globular adiponectin induces LKB1/AMPK-dependent glucose uptake via actin cytoskeleton remodeling. J Mol Endocrinol. 2013;51:155-65 pubmed publisher
product information
SKU :
3050S
Product-Name :
LKB1 (27D10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
54
Host :
Rabbit
Target :
LKB1
Primary-Protein :
LKB1
Alt-Names :
LKB1,PAR-4,PAR4,PJS,Renal carcinoma antigen NY-REN-19,STK11,Serine/threonine-protein kinase 11,Serine/threonine-protein kinase LKB1,polarization-related protein LKB1,serine/threonine kinase 11
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.