Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; fig s4b
- western blot; human; fig 1a
| Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
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- western blot knockout validation; mouse; loading ...; fig 3e
| Porat Shliom N, Tietgens A, Van Itallie C, Vitale Cross L, Jarnik M, Harding O, et al. Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo. Hepatology. 2016;64:1317-29 pubmed publisher
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- western blot knockout validation; mouse; 1:1000; fig 1
| Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig s3d
| Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 8b
| Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed publisher
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- western blot; human; loading ...; fig 5a
| Choi E, Jung B, Lee S, Yoo H, Shin E, Ko H, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017;36:5285-5295 pubmed publisher
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- western blot; mouse; fig 5B
| Kemter E, Frohlich T, Arnold G, Wolf E, Wanke R. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970 pubmed publisher
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- western blot; human; loading ...; fig 5h
| Li Z, Ivanov A, Su R, Gonzalez Pecchi V, Qi Q, Liu S, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017;8:14356 pubmed publisher
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- immunohistochemistry; mouse; loading ...; fig 1e
- western blot; mouse; loading ...; fig 1c
| Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher
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- western blot; mouse; fig 4
| Shinohara S, Gu Y, Yang Y, Furuta Y, Tanaka M, Yue X, et al. Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes. Int J Mol Med. 2016;38:574-84 pubmed publisher
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- immunoprecipitation; human; fig 1
- western blot; human; fig 1
| Ritho J, Arold S, Yeh E. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015;12:734-42 pubmed publisher
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| Soga M, Ohashi A, Taniguchi M, Matsui T, Tsuda T. The di-peptide Trp-His activates AMP-activated protein kinase and enhances glucose uptake independently of insulin in L6 myotubes. FEBS Open Bio. 2014;4:898-904 pubmed publisher
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- western blot; rat; 1:1000
| Kwon Y, Song P, Yoon J, Ghim J, Kim D, Kang B, et al. Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase. PLoS ONE. 2014;9:e108771 pubmed publisher
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| Li S, Lavagnino Z, Lemaçon D, Kong L, Ustione A, Ng X, et al. Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Mol Cell. 2019;74:1123-1137.e6 pubmed publisher
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| Kinsey C, Camolotto S, Boespflug A, Guillen K, Foth M, Truong A, et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med. 2019;25:620-627 pubmed publisher
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| Tarumoto Y, Lu B, Somerville T, Huang Y, Milazzo J, Wu X, et al. LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia. Mol Cell. 2018;69:1017-1027.e6 pubmed publisher
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| Yang K, Blanco D, Neale G, Vogel P, Avila J, Clish C, et al. Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling. Nature. 2017;548:602-606 pubmed publisher
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| Mian I, Pierre Louis W, Dole N, Gilberti R, Dodge Kafka K, Tirnauer J. LKB1 destabilizes microtubules in myoblasts and contributes to myoblast differentiation. PLoS ONE. 2012;7:e31583 pubmed publisher
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