product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-NF-κB p65 (Ser468) Antibody
catalog :
3039
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 5a
Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, et al. Redd1 knockdown prevents doxorubicin-induced cardiac senescence. Aging (Albany NY). 2021;13:13788-13806 pubmed publisher
  • western blot; mouse; loading ...; fig 3g
He S, Lu Y, Guo Y, Li S, Lu X, Shao S, et al. Krüppel-Like Factor 15 Modulates CXCL1/CXCR2 Signaling-Mediated Inflammatory Response Contributing to Angiotensin II-Induced Cardiac Remodeling. Front Cell Dev Biol. 2021;9:644954 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a, 6b
Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed publisher
  • western blot; human; loading ...; fig 5f
Luo H, Li G, Wang B, Tian B, Gao J, Zou J, et al. Peli1 signaling blockade attenuates congenital zika syndrome. PLoS Pathog. 2020;16:e1008538 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Farabaugh K, Krokowski D, Guan B, Gao Z, Gao X, Wu J, et al. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3i
Yue D, Zhao J, Chen H, Guo M, Chen C, Zhou Y, et al. MicroRNA-7, synergizes with RORα, negatively controls the pathology of brain tissue inflammation. J Neuroinflammation. 2020;17:28 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Jin Y, Li Y, Wang X, Yang Y. Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways. Cancer Cell Int. 2019;19:220 pubmed publisher
  • western blot; mouse; loading ...; fig 3a, 6d
Chen L, Kong L, Wei X, Wang Y, Wang B, Zhang X, et al. β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury. J Cell Mol Med. 2019;23:3325-3335 pubmed publisher
  • western blot; human; loading ...; fig s5g
Luo H, Winkelmann E, Zhu S, Ru W, Mays E, Silvas J, et al. Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection. J Clin Invest. 2018;128:4980-4991 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1a
Rivera Serrano E, Sherry B. NF-?B activation is cell type-specific in the heart. Virology. 2017;502:133-143 pubmed publisher
  • western blot; human; loading ...; fig 2a
Lin T, Cheng C, Su H, Huang N, Chen J, Kang H, et al. Lipopolysaccharide Attenuates Induction of Proallergic Cytokines, Thymic Stromal Lymphopoietin, and Interleukin 33 in Respiratory Epithelial Cells Stimulated with PolyI:C and Human Parechovirus. Front Immunol. 2016;7:440 pubmed
  • western blot; mouse; loading ...; fig 5a
Zhao J, Chen C, Guo M, Tao Y, Cui P, Zhou Y, et al. MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4. Front Immunol. 2016;7:389 pubmed
  • western blot; mouse; fig 6
Li J, Hardy K, Phetsouphanh C, Tu W, Sutcliffe E, McCuaig R, et al. Nuclear PKC-? facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation. J Cell Sci. 2016;129:2448-61 pubmed publisher
  • western blot; mouse; 1:500; fig 4
Chen G, Luo Y, Eriksson D, Meng X, Qian C, Bauerle T, et al. High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6. Oncotarget. 2016;7:26653-69 pubmed publisher
  • western blot; human; fig 4
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
  • western blot; human; loading ...; fig s1a
Cott C, Thuenauer R, Landi A, Kühn K, Juillot S, Imberty A, et al. Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation. Biochim Biophys Acta. 2016;1863:1106-18 pubmed publisher
  • western blot; rat; fig 4
Yuan F, Zhao M, Jiang D, Jin C, Liu H, XU M, et al. Involvement of acid-sensing ion channel 1a in matrix metabolism of endplate chondrocytes under extracellular acidic conditions through NF-κB transcriptional activity. Cell Stress Chaperones. 2016;21:97-104 pubmed publisher
Lee J, Kang Y, Chang J, Park K, Kim H, Kim J, et al. An engineered FGF21 variant, LY2405319, can prevent non-alcoholic steatohepatitis by enhancing hepatic mitochondrial function. Am J Transl Res. 2016;8:4750-4763 pubmed
Li Z, Chen Z, Zhang T, Wei C, Shi W. TGF-? and NF-?B signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging (Albany NY). 2016;8:2337-2354 pubmed publisher
product information
SKU :
3039S
Product-Name :
Phospho-NF-κB p65 (Ser468) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
65
Host :
Rabbit
Target :
NFkB-p65 (Ser468) phosphate
Primary-Protein :
NFkB-p65
Alt-Names :
MGC131774,NFKB3,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,RELA,TF65,Transcription factor p65,p65,v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)),v-rel reticuloendotheliosis viral oncogene homolog A (avian),v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.