product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-NF-κB p65 (Ser536) (7F1) Mouse mAb
catalog :
3036
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
7F1
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...
Merckx E, Albertini G, Paterka M, Jensen C, Albrecht P, Dietrich M, et al. Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis. J Neuroinflammation. 2017;14:9 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
El Hokayem J, Brittain G, Nawaz Z, Bethea J. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Mol Neurobiol. 2017;54:1301-1313 pubmed publisher
  • western blot; human
Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed publisher
  • western blot; human; fig 6
Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed publisher
  • western blot; rat; fig 8
Zhu Y, Ramos da Silva S, He M, Liang Q, Lu C, Feng P, et al. An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis. PLoS Pathog. 2016;12:e1005648 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 4e
Gómez SanMiguel A, Villanúa M, Martín A, López Calderón A. D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway. PLoS ONE. 2016;11:e0155645 pubmed publisher
  • western blot; rat; 1:1000
Tang H, Hua F, Wang J, Yousuf S, Atif F, Sayeed I, et al. Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury. Brain Inj. 2015;:1-10 pubmed
  • western blot; rat; fig 3
Bhushan S, Tchatalbachev S, Lu Y, Fröhlich S, Fijak M, Vijayan V, et al. Differential activation of inflammatory pathways in testicular macrophages provides a rationale for their subdued inflammatory capacity. J Immunol. 2015;194:5455-64 pubmed publisher
  • western blot; human; fig 6
Yang Y, Kim D, Seo Y, Park D, Jang H, Choi S, et al. Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling. Oncotarget. 2015;6:12529-42 pubmed
  • western blot; human; loading ...; fig 4
Xu H, Cho S, Bang M, Bae C, Choi Y, Li Y, et al. FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression. Int J Oncol. 2015;46:2309-16 pubmed publisher
  • western blot; human
Cang D, Guo K, Zhao F. Dendritic cells enhance UHMWPE wear particle-induced osteoclast differentiation of macrophages. J Biomed Mater Res A. 2015;103:3349-54 pubmed publisher
  • western blot; human
Bawadekar M, de Andrea M, Lo Cigno I, Baldanzi G, Caneparo V, Graziani A, et al. The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation. J Interferon Cytokine Res. 2015;35:441-53 pubmed publisher
  • immunohistochemistry; rat
Pranski E, Dalal N, Sanford C, Herskowitz J, Gearing M, Lazo C, et al. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-?B signaling in dopaminergic cells. Neurobiol Dis. 2013;54:264-79 pubmed publisher
  • western blot; human
Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice. J Biol Chem. 2013;288:1953-66 pubmed publisher
Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, et al. Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis. Physiol Rep. 2017;5: pubmed publisher
Bai X, Yang Q, Shu W, Wang J, Zhang L, Ma J, et al. Prostaglandin E2 upregulates ?1 integrin expression via the E prostanoid 1 receptor/nuclear factor ?-light-chain-enhancer of activated B cells pathway in non-small-cell lung cancer cells. Mol Med Rep. 2014;9:1729-36 pubmed publisher
Ní Gabhann J, Hams E, Smith S, Wynne C, Byrne J, Brennan K, et al. Btk regulates macrophage polarization in response to lipopolysaccharide. PLoS ONE. 2014;9:e85834 pubmed publisher
Pranski E, Van Sanford C, Dalal N, Orr A, Karmali D, Cooper D, et al. NF-?B activity is inversely correlated to RNF11 expression in Parkinson's disease. Neurosci Lett. 2013;547:16-20 pubmed publisher
Li Y, Yan J, Xu W, Wang H, Xia Y, Wang H, et al. ADAM17 mediates MMP9 expression in lung epithelial cells. PLoS ONE. 2013;8:e51701 pubmed publisher
Rajendrasozhan S, Chung S, Sundar I, Yao H, Rahman I. Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling. Am J Physiol Lung Cell Mol Physiol. 2010;298:L197-209 pubmed publisher
product information
SKU :
3036S
Product-Name :
Phospho-NF-κB p65 (Ser536) (7F1) Mouse mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, Mi, (Dg)
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
65
Host :
Mouse
Target :
NFkB-p65 (Ser536) phosphate
Primary-Protein :
NFkB-p65
Alt-Names :
MGC131774,NFKB3,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,RELA,TF65,Transcription factor p65,p65,v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)),v-rel reticuloendotheliosis viral oncogene homolog A (avian),v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.