| Published Application/Species/Dilution | Reference |
|---|
- western blot; human; fig 5
| Heynen G, Nevedomskaya E, Palit S, Jagalur Basheer N, Lieftink C, Schlicker A, et al. Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma. Mol Cancer Res. 2016;14:411-22 pubmed publisher |
- western blot; human; fig 4
| Luey B, May F. Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway. Mol Cancer. 2016;15:8 pubmed publisher |
| Cieniewicz A, Cooper P, MCGEHEE J, Lingham R, Kihm A. Novel method demonstrates differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation. Cell Signal. 2016;28:1037-47 pubmed publisher |
- western blot; human; 1:1000; fig 3
- western blot; mouse; 1:1000; fig 1
| Ding M, Bruick R, Yu Y. Secreted IGFBP5 mediates mTORC1-dependent feedback inhibition of IGF-1 signalling. Nat Cell Biol. 2016;18:319-27 pubmed publisher |
- western blot; mouse; fig 5
| Winnay J, Solheim M, Dirice E, Sakaguchi M, Noh H, Kang H, et al. PI3-kinase mutation linked to insulin and growth factor resistance in vivo. J Clin Invest. 2016;126:1401-12 pubmed publisher |
- western blot; human
- immunocytochemistry; human
| Balhara B, Burkart A, Topcu V, Lee Y, Cowan C, Kahn C, et al. Severe insulin resistance alters metabolism in mesenchymal progenitor cells. Endocrinology. 2015;156:2039-48 pubmed publisher |
- western blot; human; fig 3
| Shen Y, Zeng L, Novosyadlyy R, Forest A, Zhu A, Korytko A, et al. A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation. MAbs. 2015;7:931-45 pubmed publisher |
- western blot; human; 0.089 ug/ml; fig 4
| Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed publisher |
- immunohistochemistry; mouse
- western blot; mouse
| Tan X, Xue Y, Ma T, Wang X, Li J, Lan L, et al. Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment. Mol Neurodegener. 2015;10:24 pubmed publisher |
| Subramani R, Lopez-Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher |
- western blot; mouse; 1:1000
| Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed publisher |
| Jacobo S, DeAngelis M, Kim I, Kazlauskas A. Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1. Mol Cell Biol. 2013;33:1976-90 pubmed publisher |
| Li J, Ferry R, Diao S, Xue B, Bahouth S, Liao F. Nedd4 haploinsufficient mice display moderate insulin resistance, enhanced lipolysis, and protection against high-fat diet-induced obesity. Endocrinology. 2015;156:1283-91 pubmed publisher |
| Verhagen H, de Leeuw D, Roemer M, Denkers F, Pouwels W, Rutten A, et al. IGFBP7 induces apoptosis of acute myeloid leukemia cells and synergizes with chemotherapy in suppression of leukemia cell survival. Cell Death Dis. 2014;5:e1300 pubmed publisher |
| Li J, Dolios G, Wang R, Liao F. Soluble beta-amyloid peptides, but not insoluble fibrils, have specific effect on neuronal microRNA expression. PLoS ONE. 2014;9:e90770 pubmed publisher |
| Baloucoune G, Chun L, Zhang W, Xu C, Huang S, Sun Q, et al. GABAB receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation. PLoS ONE. 2012;7:e39698 pubmed publisher |
| Rikhof B, van der Graaf W, Suurmeijer A, van Doorn J, Meersma G, Groenen P, et al. 'Big'-insulin-like growth factor-II signaling is an autocrine survival pathway in gastrointestinal stromal tumors. Am J Pathol. 2012;181:303-12 pubmed publisher |
| Emaduddin M, Bicknell D, Bodmer W, Feller S. Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells. Proc Natl Acad Sci U S A. 2008;105:2358-62 pubmed publisher |
| Sarfstein R, Bruchim I, Fishman A, Werner H. The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway. PLoS ONE. 2011;6:e24468 pubmed publisher |
| Fei Z, Bera T, Liu X, Xiang L, Pastan I. Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts. J Biol Chem. 2011;286:27761-8 pubmed publisher |
| Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, et al. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis. 2012;2012:321280 pubmed |
