product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Insulin Receptor β (L55B10) Mouse mAb
catalog :
3020
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L55B10
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4j
López Gambero A, Rosell Valle C, Medina Vera D, Navarro J, Vargas A, Rivera P, et al. A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer's Disease, the 5XFAD Mouse. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; mouse; loading ...; fig s7a
Bi P, Ramirez Martinez A, Li H, Cannavino J, McAnally J, Shelton J, et al. Control of muscle formation by the fusogenic micropeptide myomixer. Science. 2017;356:323-327 pubmed publisher
  • immunoprecipitation; mouse; fig 3
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 3
Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed publisher
  • western blot; human; fig 8
Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Barone E, Di Domenico F, Cassano T, Arena A, Tramutola A, Lavecchia M, et al. Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm. Free Radic Biol Med. 2016;91:127-42 pubmed publisher
  • western blot; human; loading ...; fig 4a
Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, et al. Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition. Mar Drugs. 2015;13:4452-69 pubmed publisher
  • western blot; mouse; 1:1000
Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed publisher
Mohammad A, Assadian S, Couture F, Lefebvre K, El Assaad W, Barrès V, et al. V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss. Oncotarget. 2019;10:4923-4936 pubmed publisher
Ito D, Hannigan K, Ghosh D, Xu B, Del Villar S, Xiang Y, et al. β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes. J Physiol. 2019;597:2139-2162 pubmed publisher
Luo J, Xu Q, Jiang B, Zhang R, Jia X, Li X, et al. Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as PTP1B inhibitor. Br J Pharmacol. 2017;: pubmed publisher
Softic S, Gupta M, Wang G, Fujisaka S, O Neill B, Rao T, et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017;127:4059-4074 pubmed publisher
Ismail M, Mateos L, Maioli S, Merino Serrais P, Ali Z, Lodeiro M, et al. 27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation. J Exp Med. 2017;214:699-717 pubmed publisher
Reygner J, Lichtenberger L, Elmhiri G, Dou S, Bahi Jaber N, Rhazi L, et al. Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats. PLoS ONE. 2016;11:e0164614 pubmed publisher
Lao Peregrín C, Ballesteros J, Fernández M, Zamora Moratalla A, Saavedra A, Gomez Lazaro M, et al. Caffeine-mediated BDNF release regulates long-term synaptic plasticity through activation of IRS2 signaling. Addict Biol. 2017;22:1706-1718 pubmed publisher
Chan E, Chen C, Cole G, Wong B. Differential interaction of Apolipoprotein-E isoforms with insulin receptors modulates brain insulin signaling in mutant human amyloid precursor protein transgenic mice. Sci Rep. 2015;5:13842 pubmed publisher
Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, et al. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis. 2012;2012:321280 pubmed publisher
product information
SKU :
3020S
Product-Name :
Insulin Receptor β (L55B10) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
95
Host :
Mouse
Target :
INSR (beta)
Primary-Protein :
InsR
Alt-Names :
CD220,HHF5,INSR,IR,Insulin receptor,Insulin receptor subunit alpha,Insulin receptor subunit beta
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.