product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IGF-I Receptor β (111A9) Rabbit mAb
catalog :
3018
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
111A9
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 7d
Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
  • western blot; human; fig 3
Shen Y, Zeng L, Novosyadlyy R, Forest A, Zhu A, Korytko A, et al. A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation. MAbs. 2015;7:931-45 pubmed publisher
  • western blot; human; 1:1000; fig 2
Sharon C, Baranwal S, Patel N, Rodriguez Agudo D, Pandak W, Majumdar A, et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. Oncotarget. 2015;6:15332-47 pubmed
Zhou X, Yu J, Cheng X, Zhao B, Manyam G, Zhang L, et al. The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming. Nat Immunol. 2019;20:879-889 pubmed publisher
Kurlawala Z, Shah P, Shah C, Beverly L. The STI and UBA Domains of UBQLN1 Are Critical Determinants of Substrate Interaction and Proteostasis. J Cell Biochem. 2017;118:2261-2270 pubmed publisher
Peterse E, Cleven A, de Jong Y, Briaire de Bruijn I, Fletcher J, Danen E, et al. No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone. BMC Cancer. 2016;16:475 pubmed publisher
Wang I, Ramrattan G, Cheung V. Genetic variation in insulin-induced kinase signaling. Mol Syst Biol. 2015;11:820 pubmed publisher
Su J, Liang H, Yao W, Wang N, Zhang S, Yan X, et al. MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. PLoS ONE. 2014;9:e114420 pubmed publisher
Zacharewicz E, Della Gatta P, Reynolds J, Garnham A, Crowley T, Russell A, et al. Identification of microRNAs linked to regulators of muscle protein synthesis and regeneration in young and old skeletal muscle. PLoS ONE. 2014;9:e114009 pubmed publisher
Choi S, Kim S, Lee J, Cho E, Kim I. TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1. Oncotarget. 2014;5:9823-37 pubmed
Yen Y, Shiah S, Chu H, Hsu Y, Hsiao J, Chang J, et al. Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells. Mol Cancer. 2014;13:6 pubmed publisher
Zhang T, Niu X, Liao L, Cho E, Yang H. The contributions of HIF-target genes to tumor growth in RCC. PLoS ONE. 2013;8:e80544 pubmed publisher
Kim I, Kim S, Choi S, Lee J, Kim K, Cho E. Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling. Oncogene. 2014;33:3908-17 pubmed publisher
Sawitzky M, Zeissler A, Langhammer M, Bielohuby M, Stock P, Hammon H, et al. Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. PLoS ONE. 2012;7:e39711 pubmed publisher
Baloucoune G, Chun L, Zhang W, Xu C, Huang S, Sun Q, et al. GABAB receptor subunit GB1 at the cell surface independently activates ERK1/2 through IGF-1R transactivation. PLoS ONE. 2012;7:e39698 pubmed publisher
Raychaudhuri S. MicroRNAs overexpressed in growth-restricted rat skeletal muscles regulate the glucose transport in cell culture targeting central TGF-β factor SMAD4. PLoS ONE. 2012;7:e34596 pubmed publisher
Singh B, Xu Y, McLaughlin T, Singh V, Martinez J, Krishnan A, et al. Resistance to trophic neurite outgrowth of sensory neurons exposed to insulin. J Neurochem. 2012;121:263-76 pubmed publisher
Cheung V, Nayak R, Wang I, Elwyn S, Cousins S, Morley M, et al. Polymorphic cis- and trans-regulation of human gene expression. PLoS Biol. 2010;8: pubmed publisher
product information
SKU :
3018S
Product-Name :
IGF-I Receptor β (111A9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
95
Host :
Rabbit
Target :
IGF1R
Primary-Protein :
IGF1R
Alt-Names :
CD221,IGF-I receptor,IGF1R,IGFIR,IGFR,Insulin-like growth factor 1 receptor,Insulin-like growth factor 1 receptor alpha chain,Insulin-like growth factor 1 receptor beta chain,Insulin-like growth factor I receptor,JTK13,MGC142170,MGC142172,MGC18216,soluble IGF1R variant 1,soluble IGF1R variant 2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.