product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NF-κB2 p100/p52 (18D10) Rabbit mAb (Human Specific)
catalog :
3017
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
18D10
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s8c
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3d
Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, et al. Dendritic cells combined with doxorubicin induces immunogenic cell death and exhibits antitumor effects for osteosarcoma. Oncol Lett. 2016;11:2169-2175 pubmed
  • western blot; human; fig 1
Mehraein Ghomi F, Church D, Schreiber C, Weichmann A, Basu H, Wilding G. Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81). Genes Cancer. 2015;6:428-44 pubmed
  • western blot; human; 1:1000; fig 6
Choi J, Park B, Chi S, Bae K, Kim S, Cho S, et al. HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization. Oncotarget. 2014;5:10084-99 pubmed
  • western blot; mouse
  • western blot; human
Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger Davis S, Lee M, et al. A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-?B activation. PLoS ONE. 2014;9:e88052 pubmed publisher
Merola J, Reschke M, Pierce R, Qin L, Spindler S, Baltazar T, et al. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI Insight. 2019;4: pubmed publisher
de Jong S, Crequer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, et al. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. J Exp Med. 2018;215:2289-2310 pubmed publisher
Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, et al. Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation. Sci Rep. 2018;8:2021 pubmed publisher
Duan T, Sun W, Zhang M, Ge J, He Y, Zhang J, et al. Dietary restriction protects against diethylnitrosamine-induced hepatocellular tumorigenesis by restoring the disturbed gene expression profile. Sci Rep. 2017;7:43745 pubmed publisher
Willmann K, Klaver S, DoÄŸu F, Santos Valente E, Garncarz W, Bilic I, et al. Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity. Nat Commun. 2014;5:5360 pubmed publisher
Okemoto K, Wagner B, Meisen H, Haseley A, Kaur B, Chiocca E. STAT3 activation promotes oncolytic HSV1 replication in glioma cells. PLoS ONE. 2013;8:e71932 pubmed publisher
Koens L, Heyning F, Szepesi A, Matolcsy A, Hogendoorn P, Jansen P. Nuclear factor-?B activation in primary lymphoma of bone. Virchows Arch. 2013;462:349-54 pubmed publisher
Knights A, Fucíková J, Pasam A, Koernig S, Cebon J. Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy. Cancer Immunol Immunother. 2013;62:321-35 pubmed publisher
Van Maldegem F, Wormhoudt T, Mulder M, Oud M, Schilder Tol E, Musler A, et al. Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment. Leukemia. 2012;26:1647-53 pubmed publisher
product information
SKU :
3017P
Product-Name :
NF-κB2 p100/p52 (18D10) Rabbit mAb (Human Specific)
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, Mk
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
52 active form. 120 precursor.
Host :
Rabbit
Target :
NFkB2 p100/p52
Primary-Protein :
NFkB-p100
Alt-Names :
DNA-binding factor KBF2,H2TF1,LYT-10,LYT10,Lymphocyte translocation chromosome 10 protein,NFKB2,Nuclear factor NF-kappa-B p100 subunit,Nuclear factor NF-kappa-B p52 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2,Oncogene Lyt-10,nuclear factor of kappa light chain gene enhancer in B-cells 2,nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100),p52
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.