PI3 Kinase p110β (C33D4) Rabbit mAb | Cell Signaling Technology 3011 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

PI3 Kinase p110β (C33D4) Rabbit mAb

catalog :

3011

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

C33D4

reactivity :

human, mouse

application :

western blot, immunoprecipitation, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; fig 1	Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1a	Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
western blot; human; fig 6a	Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed publisher
western blot; human; 1:1000; loading ...; fig 6c	Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed publisher
western blot; human; fig s1	Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed publisher
western blot; human; loading ...; fig 4c	Monica V, Lo Iacono M, Bracco E, Busso S, di Blasio L, Primo L, et al. Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines. Oncotarget. 2016;7:76577-76589 pubmed publisher
western blot; human; loading ...; fig 4	Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
western blot; human	Perez García V, Redondo Muñoz J, Kumar A, Carrera A. Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity. Mol Cell Biol. 2014;34:3359-73 pubmed publisher
	Takeda A, Maher T, Zhang Y, Lanahan S, Bucklin M, Compton S, et al. Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology. Nat Commun. 2019;10:4364 pubmed publisher
	Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed publisher
	Stamatkin C, Ratermann K, Overley C, Black E. Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms. Cancer Biol Ther. 2015;16:1341-52 pubmed publisher
	Thapa N, Choi S, Tan X, Wise T, Anderson R. Phosphatidylinositol Phosphate 5-Kinase IÎ³ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth. J Biol Chem. 2015;290:18843-54 pubmed publisher
	Elfineh L, Classon C, Asplund A, Pettersson U, Kamali Moghaddam M, Lind S. Tyrosine phosphorylation profiling via in situ proximity ligation assay. BMC Cancer. 2014;14:435 pubmed publisher
	Cui W, Cai Y, Wang W, Liu Z, Wei P, Bi R, et al. Frequent copy number variations of PI3K/AKT pathway and aberrant protein expressions of PI3K subunits are associated with inferior survival in diffuse large B cell lymphoma. J Transl Med. 2014;12:10 pubmed publisher
	Sacco J, Yau T, Darling S, Patel V, Liu H, Urbé S, et al. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene. 2014;33:4265-72 pubmed publisher
	Cumberbatch M, Tang X, Beran G, Eckersley S, Wang X, Ellston R, et al. Identification of a subset of human non-small cell lung cancer patients with high PI3K? and low PTEN expression, more prevalent in squamous cell carcinoma. Clin Cancer Res. 2014;20:595-603 pubmed publisher
	Mouchemore K, Sampaio N, Murrey M, Stanley E, Lannutti B, Pixley F. Specific inhibition of PI3K p110? inhibits CSF-1-induced macrophage spreading and invasive capacity. FEBS J. 2013;280:5228-36 pubmed publisher
	Berends L, Fernandez Twinn D, Martin Gronert M, Cripps R, Ozanne S. Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue. Int J Obes (Lond). 2013;37:1051-7 pubmed publisher

product information

SKU :

3011S

Product-Name :

PI3 Kinase p110β (C33D4) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunoprecipitation

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

110

Host :

Rabbit

Target :

PI3K p110 beta

Primary-Protein :

PIK3CB

Alt-Names :

DKFZp779K1237,MGC133043,P110BETA,PI3-kinase p110 subunit beta,PI3-kinase subunit beta,PI3K,PI3K-beta,PI3KBETA,PIK3C1,PIK3CB,PK3CB,Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta,Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform,PtdIns-3-kinase p110,PtdIns-3-kinase subunit beta,PtdIns-3-kinase subunit p110-beta,catalytic phosphatidylinositol 3-kinase beta,phosphoinositide-3-kinase, catalytic, beta polypeptide

more info or order :

Cell Signaling Technology product webpage