product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p95/NBS1 Antibody
catalog :
3002
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, reverse phase protein lysate microarray
more info or order :
Cell Signaling Technology product webpage
citations: 10
Published Application/Species/Sample/DilutionReference
  • reverse phase protein lysate microarray; mouse; fig s1.b,c
Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed publisher
  • western blot; mouse; 1:1000
Shimada M, Dumitrache L, Russell H, McKinnon P. Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. EMBO J. 2015;34:2465-80 pubmed publisher
  • western blot; human; loading ...; fig 7a
Wei F, Ojo D, Lin X, Wong N, He L, Yan J, et al. BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. Oncogene. 2015;34:3063-75 pubmed publisher
  • western blot; mouse; 1:1000; fig 2b
Katyal S, Lee Y, Nitiss K, Downing S, Li Y, Shimada M, et al. Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nat Neurosci. 2014;17:813-21 pubmed publisher
Brandt S, Samartzis E, Zimmermann A, Fink D, Moch H, Noske A, et al. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer. BMC Cancer. 2017;17:44 pubmed publisher
Kondratova A, Watanabe T, Marotta M, Cannon M, Segall A, Serre D, et al. Replication fork integrity and intra-S phase checkpoint suppress gene amplification. Nucleic Acids Res. 2015;43:2678-90 pubmed publisher
Koppensteiner R, Samartzis E, Noske A, von Teichman A, Dedes I, Gwerder M, et al. Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro. PLoS ONE. 2014;9:e100041 pubmed publisher
Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes A, Yague E, et al. FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance. Oncogene. 2014;33:4144-55 pubmed publisher
Wang J, Chen J, Chen Y, Chen M, Hsieh C, Teng S, et al. Interaction between NBS1 and the mTOR/Rictor/SIN1 complex through specific domains. PLoS ONE. 2013;8:e65586 pubmed publisher
Adeyemi R, Landry S, Davis M, Weitzman M, Pintel D. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog. 2010;6:e1001141 pubmed publisher
product information
SKU :
3002S
Product-Name :
p95/NBS1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, Mi
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
95
Host :
Rabbit
Target :
p95/NBS1
Primary-Protein :
NBS1
Alt-Names :
AT-V1,AT-V2,ATV,Cell cycle regulatory protein p95,FLJ10155,MGC87362,NBN,NBS,NBS1,Nibrin,Nijmegen breakage syndrome 1 (nibrin),Nijmegen breakage syndrome protein 1,P95,p95 protein of the MRE11/RAD50 complex
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.