product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
ASF1A (C6E10) Rabbit mAb
catalog :
2990
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
C6E10
reactivity :
human, mouse, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
Huang T, Fowler F, Chen C, Shen Z, SLECKMAN B, Tyler J. The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. Mol Cell. 2018;69:879-892.e5 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 5a
  • immunocytochemistry; human; loading ...; fig 3a
  • immunohistochemistry; human; loading ...; fig 7e
  • western blot; human; loading ...; fig 4a
Liang X, Yuan X, Yu J, Wu Y, Li K, Sun C, et al. Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes. EBioMedicine. 2017;21:104-116 pubmed publisher
  • western blot; human; loading ...; fig 2f
Yang C, Sengupta S, Hegde P, Mitra J, Jiang S, Holey B, et al. Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A. Nucleic Acids Res. 2017;45:739-748 pubmed publisher
  • western blot; human; loading ...; fig 3b
Liu Z, Yang L, Sun Y, Xie X, Huang J. ASF1a enhances antiviral immune response by associating with CBP to mediate acetylation of H3K56 at the Ifnb promoter. Mol Immunol. 2016;78:57-64 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 5a
Yang J, Song T, Jo C, Park J, Lee H, Song I, et al. Differential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch. Exp Mol Med. 2016;48:e252 pubmed publisher
Wu Y, Li X, Yu J, Bjorkholm M, Xu D. ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells. Cell Death Dis. 2019;10:76 pubmed publisher
Campeau E, Ruhl V, Rodier F, Smith C, Rahmberg B, FUSS J, et al. A versatile viral system for expression and depletion of proteins in mammalian cells. PLoS ONE. 2009;4:e6529 pubmed publisher
product information
SKU :
2990S
Product-Name :
ASF1A (C6E10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk, (C, B)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
20 kDa
Host :
Rabbit
Target :
Asf1a
Primary-Protein :
ASF1A
Alt-Names :
ASF1 anti-silencing function 1 homolog A (S. cerevisiae),ASF1A,Anti-silencing function protein 1 homolog A,CCG1-interacting factor A,CGI-98,CIA,DKFZp547E2110,HSPC146,Histone chaperone ASF1A,anti-silencing function 1A,hAsf1,hAsf1a,hCIA
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.