| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 8a
| Figueiredo M, Daryadel A, Sihn G, Muller D, Popova E, Rouselle A, et al. The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule. Pflugers Arch. 2021;473:1229-1246 pubmed publisher |
- immunohistochemistry; human; fig s4e
| Chen C, Hsu S, Chung T, Chu C, Wang H, Hsiao P, et al. Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells. Nat Commun. 2021;12:2398 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Yagisawa Y, Suita K, Ohnuki Y, Ishikawa M, Mototani Y, Ito A, et al. Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice. PLoS ONE. 2020;15:e0236547 pubmed publisher |
- western blot; mouse; loading ...; fig 3c
| Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2a
| Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 3a
| Basu R, Wu S, Kopchick J. Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways. Oncotarget. 2017;8:21579-21598 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3d
| Cooper H, Yang Y, Ylikallio E, Khairullin R, Woldegebriel R, Lin K, et al. ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia. Hum Mol Genet. 2017;26:1432-1443 pubmed publisher |
- western blot; human; fig 1
| Navarro Villarán E, Tinoco J, Jiménez G, Pereira S, Wang J, Aliseda S, et al. Differential Antitumoral Properties and Renal-Associated Tissue Damage Induced by Tacrolimus and Mammalian Target of Rapamycin Inhibitors in Hepatocarcinoma: In Vitro and In Vivo Studies. PLoS ONE. 2016;11:e0160979 pubmed publisher |
- western blot; mouse; 1:2000; fig 3
| Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher |
- western blot; human; fig 4b
| Warner M, Bridge K, Hewitson J, Hodgkinson M, Heyam A, Massa B, et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res. 2016;44:9942-9955 pubmed |
- immunocytochemistry; human; fig 3
| Bento C, Ashkenazi A, Jimenez Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed publisher |
- western blot; mouse; fig 5a
| Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher |
- western blot; mouse; fig 7
| Verbist K, Guy C, Milasta S, Liedmann S, Kaminski M, Wang R, et al. Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. Nature. 2016;532:389-93 pubmed publisher |
- western blot; mouse; loading ...; fig 2b
| Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher |
- western blot; rat; 1:1000; fig 6
| Li J, Huang S, Zhang J, Feng C, Gao D, Yao B, et al. Mesenchymal stem cells ameliorate inflammatory cytokine-induced impairment of AT-II cells through a keratinocyte growth factor-dependent PI3K/Akt/mTOR signaling pathway. Mol Med Rep. 2016;13:3755-62 pubmed publisher |
- western blot; human; fig 5
| Hayashi K, Michiue H, Yamada H, Takata K, Nakayama H, Wei F, et al. Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization. Sci Rep. 2016;6:23372 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1a
| Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 2c
- western blot; human; 1:1000-1:5000; loading ...; fig 1b
| Lai Y, Yu X, Lin X, He S. Inhibition of mTOR sensitizes breast cancer stem cells to radiation-induced repression of self-renewal through the regulation of MnSOD and Akt. Int J Mol Med. 2016;37:369-77 pubmed publisher |
- western blot; human; 1:1000; tbl 1
| Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Verbrugge S, Al M, Assaraf Y, Kammerer S, Chandrupatla D, Honeywell R, et al. Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR. Oncotarget. 2016;7:5240-57 pubmed publisher |
- western blot; mouse; 1:500
| Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher |
| Pan B, Zhang H, Cui T, Wang X. TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux. J Mol Cell Cardiol. 2017;113:51-62 pubmed publisher |
| Chakraborty D, Benham V, Bullard B, Kearney T, Hsia H, Gibbon D, et al. Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene. 2017;36:6668-6679 pubmed publisher |
| Zheng K, Jiang Y, Liao C, Hu X, Li Y, Zeng Y, et al. NOX2-Mediated TFEB Activation and Vacuolization Regulate Lysosome-Associated Cell Death Induced by Gypenoside L, a Saponin Isolated from Gynostemma pentaphyllum. J Agric Food Chem. 2017;65:6625-6637 pubmed publisher |
| Pawlak A, Ziolo E, Fiedorowicz A, Fidyt K, Strzadala L, Kalas W. Long-lasting reduction in clonogenic potential of colorectal cancer cells by sequential treatments with 5-azanucleosides and topoisomerase inhibitors. BMC Cancer. 2016;16:893 pubmed |
| Toulany M, Iida M, Keinath S, Iyi F, Mueck K, Fehrenbacher B, et al. Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer. Oncotarget. 2016;7:43746-43761 pubmed publisher |
| Bhattacharya K, Maiti S, Mandal C. PTEN negatively regulates mTORC2 formation and signaling in grade IV glioma via Rictor hyperphosphorylation at Thr1135 and direct the mode of action of an mTORC1/2 inhibitor. Oncogenesis. 2016;5:e227 pubmed publisher |
| Zhao M, Lu L, Lei S, Chai H, Wu S, Tang X, et al. Inhibition of Receptor Interacting Protein Kinases Attenuates Cardiomyocyte Hypertrophy Induced by Palmitic Acid. Oxid Med Cell Longev. 2016;2016:1451676 pubmed publisher |
