Phospho-mTOR (Ser2448) Antibody | Cell Signaling Technology 2971S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-mTOR (Ser2448) Antibody

catalog :

2971S

quantity :

100 ul

price :

274 USD

clonality :

polyclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

gilthead bream, human, mouse, rat, dog, chicken, cat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, other

more info or order :

Cell Signaling Technology product webpage

citations: 87

Published Application/Species/Dilution	Reference
western blot; mouse; fig 6	Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;: pubmed publisher
western blot; human; 1:1000; fig 6	Verbrugge S, Al M, Assaraf Y, Kammerer S, Chandrupatla D, Honeywell R, et al. Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR. Oncotarget. 2016;7:5240-57 pubmed publisher
western blot; mouse; 1:1000; tbl 1	Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
western blot; mouse; 1:1000; fig 2	Walter C, Clemens L, Müller A, Fallier-Becker P, Proikas-Cezanne T, Riess O, et al. Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro. Neuropharmacology. 2016;108:24-38 pubmed publisher
western blot; human; fig 2	Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed publisher
western blot; human; 1:1000; fig 6	Dirks M, Wall B, Kramer I, Zorenc A, Goessens J, Gijsen A, et al. A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion. Am J Physiol Endocrinol Metab. 2016;:ajpendo.00085.2016 pubmed publisher
western blot; dog; 1:1000; fig 3A	Domínguez-Calderón A, Avila-Flores A, Ponce A, Lopez-Bayghen E, Calderón-Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed publisher
western blot; mouse; 1:500; fig 4	Suman S, Kumar S, Fornace A, Datta K. Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine. Sci Rep. 2016;6:31853 pubmed publisher
western blot; mouse; 1:500	Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher
western blot; rat; 1:1000; fig 5	Liu L, Wang C, Lin Y, Xi Y, Li H, Shi S, et al. Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Mol Med Rep. 2016;14:111-20 pubmed publisher
western blot; human; fig 2	Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher
western blot; human; fig 5d	Wang X, Tang Z, Yu D, Cui S, Jiang Y, Zhang Q, et al. Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma. Oncotarget. 2016;7:8823-38 pubmed publisher
western blot; rat; fig 10	Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;: pubmed
western blot; human; 1:1000; tbl 1	Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont-Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
western blot; human; fig 3	Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
western blot; mouse; fig s1	Gómez-Sánchez R, Yakhine-Diop S, Bravo-San Pedro J, Pizarro-Estrella E, Rodríguez-Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed publisher
western blot; mouse; fig 7	Wang X, Bey A, Katz B, Badea A, Kim N, David L, et al. Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism. Nat Commun. 2016;7:11459 pubmed publisher
western blot; human; 1:1000; fig st1	Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
western blot; human; fig s2	Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed publisher
western blot; human; fig 4	Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher
western blot; mouse; fig 4	Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, et al. EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016;6:396-410 pubmed publisher
western blot; human; fig 2	Thomassen M, Gunnarsson T, Christensen P, Pavlovic D, Shattock M, Bangsbo J. Intensive training and reduced volume increases muscle FXYD1 expression and phosphorylation at rest and during exercise in athletes. Am J Physiol Regul Integr Comp Physiol. 2016;310:R659-69 pubmed publisher
western blot; human; 1:1000	Panneerselvam J, Jin J, Shanker M, Lauderdale J, BATES J, Wang Q, et al. IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis. PLoS ONE. 2015;10:e0122439 pubmed publisher
western blot; human	Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2015;: pubmed publisher
western blot; rat; 1:1000	Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
western blot; mouse; fig 6	Lin C, Chen Y, Lin C, Chen Y, Lo G, Lee P, et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015;5:15807 pubmed publisher
immunohistochemistry; mouse; 1:200	Bernard-Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B. Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice. Neurobiol Dis. 2015;73:130-6 pubmed publisher
western blot; human; fig 1	Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
western blot; human	Ma Y, Han W, Li J, Hu L, Zhou Y. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36:517-27 pubmed publisher
western blot; rat	Park B, Cha S, Han B, Kim S. Angiotensin IV stimulates high atrial stretch-induced ANP secretion via insulin regulated aminopeptidase. Peptides. 2015;63:30-7 pubmed publisher
western blot; rat; 1:2000	Ledonne A, Nobili A, Latagliata E, Cavallucci V, Guatteo E, Puglisi-Allegra S, et al. Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. Mol Psychiatry. 2015;20:959-73 pubmed publisher
western blot; rat immunocytochemistry; human	Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
western blot; rat	Liu H, Xie Q, Xin B, Liu J, Liu Y, Li Y, et al. Inhibition of autophagy recovers cardiac dysfunction and atrophy in response to tail-suspension. Life Sci. 2015;121:1-9 pubmed publisher
western blot; rat; 1:1000; fig 2e	Chen K, Tsai M, Wu C, Jou M, Wei I, Huang C. AMPA Receptor-mTOR Activation is Required for the Antidepressant-Like Effects of Sarcosine during the Forced Swim Test in Rats: Insertion of AMPA Receptor may Play a Role. Front Behav Neurosci. 2015;9:162 pubmed publisher
western blot; human; fig 4	Tsutsumi Y, Nomiyama T, Kawanami T, Hamaguchi Y, Terawaki Y, Tanaka T, et al. Combined Treatment with Exendin-4 and Metformin Attenuates Prostate Cancer Growth. PLoS ONE. 2015;10:e0139709 pubmed publisher
western blot; mouse western blot; rat	Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed publisher
other; mouse; 1:1000; fig s1	Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
western blot; mouse; fig 5e	Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed publisher
western blot; human; 1:1000	Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
immunohistochemistry; human; 1:2000	Jespersen J, Mikkelsen U, Nedergaard A, Thorlund J, Schjerling P, Suetta C, et al. Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission. Scand J Med Sci Sports. 2015;25:175-83 pubmed publisher
western blot; human; 1:1000; fig 4b	Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
western blot; rat; 1:1000	Gomez A, Gomez J, Lopez Torres M, Naudi A, Mota-Martorell N, Pamplona R, et al. Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction. J Bioenerg Biomembr. 2015;47:199-208 pubmed publisher
western blot; mouse; fig s2	Dutchak P, Laxman S, Estill S, Wang C, Wang Y, Wang Y, et al. Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2. Cell Rep. 2015;12:371-9 pubmed publisher
western blot; mouse; 1:1000; fig 6	Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015;18:826-35 pubmed publisher
western blot; chicken; fig 4	Nguyen P, GREENE E, Ishola P, Huff G, Donoghue A, Bottje W, et al. Chronic Mild Cold Conditioning Modulates the Expression of Hypothalamic Neuropeptide and Intermediary Metabolic-Related Genes and Improves Growth Performances in Young Chicks. PLoS ONE. 2015;10:e0142319 pubmed publisher
western blot; human; fig 1	Ye Z, Al-Aidaroos A, Park J, Yuen H, Zhang S, Gupta A, et al. PRL-3 activates mTORC1 in Cancer Progression. Sci Rep. 2015;5:17046 pubmed publisher
western blot; human; fig 1	Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed publisher
western blot; human; fig 6	Artero-Castro A, Pérez-Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
western blot; human	Zhang L, Dai F, Cui L, Jing H, Fan P, Tan X, et al. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells. Biochim Biophys Acta. 2015;1853:377-87 pubmed publisher
western blot; mouse	Kang J, Cho H, Lee S. Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion. Cell Physiol Biochem. 2014;33:23-36 pubmed publisher
western blot; gilthead bream; 1:200	Vélez E, Lutfi E, Jiménez-Amilburu V, Riera-Codina M, Capilla E, Navarro I, et al. IGF-I and amino acids effects through TOR signaling on proliferation and differentiation of gilthead sea bream cultured myocytes. Gen Comp Endocrinol. 2014;205:296-304 pubmed publisher
western blot; mouse	Gonzalez-Rodriguez A, Mayoral R, Agra N, Valdecantos M, Pardo V, Miquilena-Colina M, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis. 2014;5:e1179 pubmed publisher
western blot; human	Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher
western blot; mouse; 1:500	Datta K, Suman S, Fornace A. Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine. Int J Biochem Cell Biol. 2014;57:167-76 pubmed publisher
western blot; mouse; 1:1000	Zhang Y, Zhang X, Gao L, Liu Y, Jiang D, Chen K, et al. Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction. Biochim Biophys Acta. 2014;1842:232-44 pubmed publisher
western blot; mouse	Bian Z, Liao H, Zhang Y, Wu Q, Zhou H, Yang Z, et al. Never in mitosis gene A related kinase-6 attenuates pressure overload-induced activation of the protein kinase B pathway and cardiac hypertrophy. PLoS ONE. 2014;9:e96095 pubmed publisher
western blot; human	Elliott V, Rychahou P, Zaytseva Y, Evers B. Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model. PLoS ONE. 2014;9:e97432 pubmed publisher
western blot; mouse; 1:1000	Areta J, Hawley J, Ye J, Chan M, Coffey V. Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells. Nutr Res. 2014;34:1000-7 pubmed publisher
western blot; human; 1:1000 western blot; rat; 1:1000	Tian H, Wang L, Cai R, Zheng L, Guo L. Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model. PLoS ONE. 2014;9:e116453 pubmed publisher
western blot; human; 1:500; fig 3	Ambrosi G, Ghezzi C, Sepe S, Milanese C, Payan-Gomez C, Bombardieri C, et al. Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease. Biochim Biophys Acta. 2014;1842:1385-94 pubmed publisher
western blot; human	Beckham T, Cheng J, Lu P, Shao Y, Troyer D, Lance R, et al. Acid ceramidase induces sphingosine kinase 1/S1P receptor 2-mediated activation of oncogenic Akt signaling. Oncogenesis. 2013;2:e49 pubmed publisher
western blot; human; 1:1000	Gong F, Peng X, Sang Y, Qiu M, Luo C, He Z, et al. Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling. Cell Death Dis. 2013;4:e913 pubmed publisher
western blot; human; 1:1000 western blot; rat; 1:1000 immunohistochemistry; rat	Jiang F, Pang X, Niu Q, Hua L, Cheng M, Ji Y. Activation of mammalian target of rapamycin mediates rat pain-related responses induced by BmK I, a sodium channel-specific modulator. Mol Pain. 2013;9:50 pubmed publisher
western blot; rat	Luo L, Lu A, Wang Y, Hong A, Chen Y, Hu J, et al. Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats. Exp Gerontol. 2013;48:427-36 pubmed publisher
western blot; human; 1:2000	Park Y, Ko J, Jang Y, Kwon Y. Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells. Neurochem Res. 2013;38:1561-71 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100 western blot; human	Kucherlapati M, Esfahani S, Habibollahi P, Wang J, Still E, Bronson R, et al. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS ONE. 2013;8:e68817 pubmed publisher
western blot; cat; 1:750	Maniscalco L, Millan Y, Iussich S, Denina M, Sánchez-Cespedes R, Gattino F, et al. Activation of mammalian target of rapamycin (mTOR) in triple negative feline mammary carcinomas. BMC Vet Res. 2013;9:80 pubmed publisher
western blot; mouse	Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed publisher
western blot; human	Chang C, Chen C, Wu M, Chen Y, Chen C, Sheu S, et al. Active Component of Antrodia cinnamomea Mycelia Targeting Head and Neck Cancer Initiating Cells through Exaggerated Autophagic Cell Death. Evid Based Complement Alternat Med. 2013;2013:946451 pubmed publisher
western blot; human; 1:500	Kyathanahalli C, Marks J, Nye K, Lao B, Albrecht E, Aberdeen G, et al. Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon. Endocrinology. 2013;154:4873-84 pubmed publisher
western blot; human	Areta J, Burke L, Ross M, Camera D, West D, Broad E, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013;591:2319-31 pubmed publisher
western blot; human	Gupta M, Dillon S, Ziesmer S, Feldman A, Witzig T, Ansell S, et al. A proliferation-inducing ligand mediates follicular lymphoma B-cell proliferation and cyclin D1 expression through phosphatidylinositol 3-kinase-regulated mammalian target of rapamycin activation. Blood. 2009;113:5206-16 pubmed publisher
western blot; human	Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed publisher
	Luo Y, Han H, Shao J, Gao Y, Yin X, Zhu W, et al. mTOR signalling in the nucleus accumbens shell is critical for augmented effect of TFF3 on behavioural response to cocaine. Sci Rep. 2016;6:27895 pubmed publisher
	Weikel K, Cacicedo J, Ruderman N, Ido Y. Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells. Am J Physiol Cell Physiol. 2015;308:C249-63 pubmed publisher
	Sosanya N, Huang P, Cacheaux L, Chen C, Nguyen K, Perrone-Bizzozero N, et al. Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1. J Cell Biol. 2013;202:53-69 pubmed publisher
	Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, et al. Haploinsufficiency of akt1 prolongs the lifespan of mice. PLoS ONE. 2013;8:e69178 pubmed publisher
	Bach E, Nielsen R, Vendelbo M, Møller A, Jessen N, Buhl M, et al. Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo-controlled, bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown, and increased IL-6 release. Diabetes. 2013;62:4023-9 pubmed publisher
	Cao Y, Tao L, Shen S, Xiao J, Wu H, Li B, et al. Cardiac ablation of Rheb1 induces impaired heart growth, endoplasmic reticulum-associated apoptosis and heart failure in infant mice. Int J Mol Sci. 2013;14:24380-98 pubmed publisher
	Hasumi Y, Baba M, Ajima R, Hasumi H, Valera V, Klein M, et al. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2. Proc Natl Acad Sci U S A. 2009;106:18722-7 pubmed publisher
	Suman S, Johnson M, Fornace A, Datta K. Exposure to ionizing radiation causes long-term increase in serum estradiol and activation of PI3K-Akt signaling pathway in mouse mammary gland. Int J Radiat Oncol Biol Phys. 2012;84:500-7 pubmed publisher
	Fei Z, Bera T, Liu X, Xiang L, Pastan I. Ankrd26 gene disruption enhances adipogenesis of mouse embryonic fibroblasts. J Biol Chem. 2011;286:27761-8 pubmed publisher
	Prieto A, O'Dell S, Varnum B, Lai C. Localization and signaling of the receptor protein tyrosine kinase Tyro3 in cortical and hippocampal neurons. Neuroscience. 2007;150:319-34 pubmed
	Shavlakadze T, Chai J, Maley K, Cozens G, Grounds G, Winn N, et al. A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo. J Cell Sci. 2010;123:960-71 pubmed publisher
	Métrailler S, Schorderet D, Cottet S. Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes. Exp Eye Res. 2012;96:70-81 pubmed publisher
	Wali J, de Boo H, Derraik J, Phua H, Oliver M, Bloomfield F, et al. Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters. PLoS ONE. 2012;7:e37899 pubmed publisher
	Mennigen J, Panserat S, Larquier M, Plagnes-Juan E, Médale F, Seiliez I, et al. Postprandial regulation of hepatic microRNAs predicted to target the insulin pathway in rainbow trout. PLoS ONE. 2012;7:e38604 pubmed publisher

product information

SKU :

2971S

Product-Name :

Phospho-mTOR (Ser2448) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk, (Hr)

Applications :

Western blot

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

289

Host :

Rabbit

Target :

mTOR (Ser2448) phosphate

Primary-Protein :

mTOR

Alt-Names :

FK506 binding protein 12-rapamycin associated protein 1,FK506 binding protein 12-rapamycin associated protein 2,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP-rapamycin associated protein,FKBP12-rapamycin complex-associated protein,FKBP12-rapamycin complex-associated protein 1,FLJ44809,FRAP,FRAP1,FRAP2,Mammalian target of rapamycin,RAFT1,RAPT1,Rapamycin target protein 1,Serine/threonine-protein kinase mTOR,mTOR,mechanistic target of rapamycin (serine/threonine kinase),rapamycin and FKBP12 target 1,rapamycin associated protein FRAP2

more info or order :

Cell Signaling Technology product webpage