product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Akt1 (2H10) Mouse mAb
catalog :
2967S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
2H10
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Kumar A, Abbas W, Colin L, Khan K, Bouchat S, Varin A, et al. Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Sci Rep. 2016;6:24090 pubmed publisher
  • western blot; human
Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed publisher
  • western blot; rat
Longman M, Ranieri A, Avkiran M, Snabaitis A. Regulation of PP2AC carboxylmethylation and cellular localisation by inhibitory class G-protein coupled receptors in cardiomyocytes. PLoS ONE. 2014;9:e86234 pubmed publisher
  • western blot; human
Bijian K, Lougheed C, Su J, Xu B, Yu H, Wu J, et al. Targeting focal adhesion turnover in invasive breast cancer cells by the purine derivative reversine. Br J Cancer. 2013;109:2810-8 pubmed publisher
Zhang W, Zhang X, Gonzalez-Cobos J, Stolwijk J, Matrougui K, Trebak M. Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia. J Biol Chem. 2015;290:5015-27 pubmed publisher
Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, et al. Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation. J Biol Chem. 2014;289:26302-13 pubmed publisher
Umeshappa C, Xie Y, Xu S, Nanjundappa R, Freywald A, Deng Y, et al. Th cells promote CTL survival and memory via acquired pMHC-I and endogenous IL-2 and CD40L signaling and by modulating apoptosis-controlling pathways. PLoS ONE. 2013;8:e64787 pubmed publisher
Chinn D, Holland W, Yoon J, Zwerdling T, Mack P. Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines. Pediatr Blood Cancer. 2012;58:885-90 pubmed publisher
Brown J, Bell T, Alger H, Sawyer J, Smith T, Kelley K, et al. Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss. J Biol Chem. 2008;283:10522-34 pubmed publisher
Lessard S, Rivas D, Chen Z, Bonen A, Febbraio M, Reeder D, et al. Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance. Diabetes. 2007;56:1856-64 pubmed
Popkie A, Zeidner L, Albrecht A, D'Ippolito A, Eckardt S, Newsom D, et al. Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci. J Biol Chem. 2010;285:41337-47 pubmed publisher
Sully K, Akinduro O, Philpott M, Naeem A, Harwood C, Reeve V, et al. The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling. Oncogene. 2013;32:3254-62 pubmed publisher
Brown J, Chung S, Das A, Shelness G, Rudel L, Yu L. CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cells. J Lipid Res. 2007;48:2295-305 pubmed
Vaidya K, Sanchez J, Kim E, Welch D. Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells. Cancer Lett. 2009;281:100-7 pubmed publisher
product information
SKU :
2967S
Product-Name :
Akt1 (2H10) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Mouse
Target :
Akt1
Primary-Protein :
Akt1
Alt-Names :
AKT,AKT1,AKT1 kinase,MGC99656,PKB,PKB-ALPHA,PRKBA,Protein kinase B,Proto-oncogene c-Akt,RAC,RAC-ALPHA,RAC-PK-alpha,RAC-alpha serine/threonine-protein kinase,rac protein kinase alpha,v-akt murine thymoma viral oncogene homolog 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.