product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Akt (5G3) Mouse mAb
catalog :
2966
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5G3
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 4h
Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed publisher
  • western blot; human; loading ...; fig 5e
Xu J, Zhang X, Wang H, Ge S, Gao T, Song L, et al. HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition. Biomed Pharmacother. 2017;88:421-429 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig 14
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
  • western blot; rat; 1:500; fig 3
Jia W, Jian Z, Li J, Luo L, Zhao L, Zhou Y, et al. Upregulated ATF6 contributes to chronic intermittent hypoxia-afforded protection against myocardial ischemia/reperfusion injury. Int J Mol Med. 2016;37:1199-208 pubmed publisher
  • western blot; human; fig 5
Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed publisher
  • western blot; human; 1:1000; fig 4
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
  • western blot; human; loading ...; fig 2a
Liao B, McManus S, Hughes W, Schmitz Peiffer C. Flavin-Containing Monooxygenase 3 Reduces Endoplasmic Reticulum Stress in Lipid-Treated Hepatocytes. Mol Endocrinol. 2016;30:417-28 pubmed publisher
  • western blot; mouse; 1:2000
Tang Y, Ye M, Du Y, Qiu X, Lv X, Yang W, et al. EGFR signaling upregulates surface expression of the GluN2B-containing NMDA receptor and contributes to long-term potentiation in the hippocampus. Neuroscience. 2015;304:109-21 pubmed publisher
  • western blot; human; fig 3
Sun J, Lu F, He H, Shen J, Messina J, Mathew R, et al. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. J Cell Biol. 2014;207:535-48 pubmed publisher
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
Matsuda Lennikov M, Suizu F, Hirata N, Hashimoto M, Kimura K, Nagamine T, et al. Lysosomal interaction of Akt with Phafin2: a critical step in the induction of autophagy. PLoS ONE. 2014;9:e79795 pubmed publisher
García de la serrana D, Johnston I. Expression of heat shock protein (Hsp90) paralogues is regulated by amino acids in skeletal muscle of Atlantic salmon. PLoS ONE. 2013;8:e74295 pubmed publisher
Oaks A, Frankfurt M, Finkelstein D, Sidhu A. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS ONE. 2013;8:e60378 pubmed publisher
So J, Smolarek A, Salerno D, Maehr H, Uskokovic M, Liu F, et al. Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer. PLoS ONE. 2013;8:e54020 pubmed publisher
García de la serrana D, Vieira V, Andree K, Darias M, Estévez A, Gisbert E, et al. Development temperature has persistent effects on muscle growth responses in gilthead sea bream. PLoS ONE. 2012;7:e51884 pubmed publisher
Javle M, Shroff R, Xiong H, Varadhachary G, Fogelman D, Reddy S, et al. Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies. BMC Cancer. 2010;10:368 pubmed publisher
product information
SKU :
2966L
Product-Name :
Akt (5G3) Mouse mAb
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M, R, Hm
Applications :
Flow cytometry
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Mouse
Target :
Akt1/Akt3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.