product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Akt1 (C73H10) Rabbit mAb
catalog :
2938S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, rabbit
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 25
Published Application/Species/DilutionReference
  • western blot; mouse; fig 6
Gu K, Zhang Q, Yan Y, Li T, Duan F, Hao J, et al. Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency. Cell Res. 2016;26:350-66 pubmed publisher
  • western blot; human; 1:500; fig 4
Fabbri R, Macciocca M, Vicenti R, Paradisi R, Klinger F, Pasquinelli G, et al. Doxorubicin and cisplatin induce apoptosis in ovarian stromal cells obtained from cryopreserved human ovarian tissue. Future Oncol. 2016;12:1699-711 pubmed publisher
  • western blot; human; fig 2
Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed publisher
  • western blot; mouse
Bisson J, Mills B, Paul Helt J, Zwaka T, Cohen E. Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT. Dev Biol. 2015;398:80-96 pubmed publisher
  • western blot; rat; fig s3
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed
  • western blot; human
Peres J, Mowla S, Prince S. The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis. Oncotarget. 2015;6:1821-33 pubmed
  • western blot; human; 1:1000
Hellesøy M, Lorens J. Cellular context-mediated Akt dynamics regulates MAP kinase signaling thresholds during angiogenesis. Mol Biol Cell. 2015;26:2698-711 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
  • western blot; rat; 1:1000
Li M, Yang S, Xing B, Ferguson B, Gulchina Y, Li Y, et al. LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment. Exp Neurol. 2015;273:190-201 pubmed publisher
  • western blot; rat; 1:1000
Ledonne A, Nobili A, Latagliata E, Cavallucci V, Guatteo E, Puglisi-Allegra S, et al. Neuregulin 1 signalling modulates mGluR1 function in mesencephalic dopaminergic neurons. Mol Psychiatry. 2015;20:959-73 pubmed publisher
  • western blot; human; fig 4
Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher
  • western blot; rat
Dongiovanni P, Lanti C, Gatti S, Rametta R, Recalcati S, Maggioni M, et al. High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload. PLoS ONE. 2015;10:e0116855 pubmed publisher
  • western blot; mouse; 1:1000
Major J, Salih M, Tuana B. Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium. J Mol Cell Cardiol. 2015;84:179-90 pubmed publisher
  • western blot; mouse
Seo K, Lee S, Ye B, Kim Y, Bae S, Kim C. Mechanical stretch enhances the expression and activity of osteopontin and MMP-2 via the Akt1/AP-1 pathways in VSMC. J Mol Cell Cardiol. 2015;85:13-24 pubmed publisher
  • western blot; rabbit; 1:2,000
Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed publisher
  • western blot; human; 1:1000
Ninio-Many L, Grossman H, Levi M, Zilber S, Tsarfaty I, Shomron N, et al. MicroRNA miR-125a-3p modulates molecular pathway of motility and migration in prostate cancer cells. Oncoscience. 2014;1:250-61 pubmed
  • western blot; rat; 1:1000
Morgan K, Black L. Mimicking isovolumic contraction with combined electromechanical stimulation improves the development of engineered cardiac constructs. Tissue Eng Part A. 2014;20:1654-67 pubmed publisher
  • western blot; mouse
O'Brien T, Gorentla B, Xie D, Srivatsan S, McLeod I, He Y, et al. Regulation of T-cell survival and mitochondrial homeostasis by TSC1. Eur J Immunol. 2011;41:3361-70 pubmed publisher
Xu T, Su B, Wang C, Wang S, Huang H, Pan Y, et al. Molecular markers to assess short-term disease local recurrence in nasopharyngeal carcinoma. Oncol Rep. 2015;33:1418-26 pubmed publisher
Dobashi Y, Sato E, Oda Y, Inazawa J, Ooi A. Significance of Akt activation and AKT gene increases in soft tissue tumors. Hum Pathol. 2014;45:127-36 pubmed publisher
Al-Khalaf H, Aboussekhra A. MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor ZEB1 and the protein kinase AKT. J Biol Chem. 2014;289:31433-47 pubmed publisher
Katayama R, Aoyama A, Yamori T, Qi J, Oh-hara T, Song Y, et al. Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition. Cancer Res. 2013;73:3087-96 pubmed publisher
Tsen F, Bhatia A, O'Brien K, Cheng C, Chen M, Hay N, et al. Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol Cell Biol. 2013;33:4947-59 pubmed publisher
Mahajan K, Coppola D, Challa S, Fang B, Chen Y, Zhu W, et al. Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. PLoS ONE. 2010;5:e9646 pubmed publisher
Carlin L, Evans R, Milewicz H, Fernandes L, Matthews D, Perani M, et al. A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. Sci Signal. 2011;4:ra81 pubmed publisher
product information
SKU :
2938S
Product-Name :
Akt1 (C73H10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Akt1
Primary-Protein :
Akt1
Alt-Names :
AKT,AKT1,AKT1 kinase,MGC99656,PKB,PKB-ALPHA,PRKBA,Protein kinase B,Proto-oncogene c-Akt,RAC,RAC-ALPHA,RAC-PK-alpha,RAC-alpha serine/threonine-protein kinase,rac protein kinase alpha,v-akt murine thymoma viral oncogene homolog 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.