| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 3c
| Choiniere J, Wu J, Wang L. Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. Mol Pharmacol. 2017;91:189-196 pubmed publisher |
- western blot; human; 1:200; loading ...; fig 5a
| Su Y, Xu J, Gao R, Liu X, Liu T, Li C, et al. The Circ-CYP24A1-miR-224-PRLR Axis Impairs Cell Proliferation and Apoptosis in Recurrent Miscarriage. Front Physiol. 2022;13:778116 pubmed publisher |
- western blot; human; loading ...; fig 3e
| Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3b
| Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher |
- western blot; mouse; loading ...; fig 4b
| Chen A, Santana A, Doudican N, Roudiani N, Laursen K, Therrien J, et al. MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation. PLoS ONE. 2020;15:e0241551 pubmed publisher |
- western blot; mouse; loading ...; fig 5e
| Tan Y, Sementino E, Liu Z, Cai K, Testa J. Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis. Sci Rep. 2020;10:15837 pubmed publisher |
- western blot; human; loading ...; fig 4
| Lee S, Hong K, Seong Y, Kwak S. Ectopic Overexpression of Coiled-Coil Domain Containing 110 Delays G2/M Entry in U2-OS Cells. Dev Reprod. 2020;24:101-111 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 5f
| Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 5f
| Zhuo Z, Wan Y, Guan D, Ni S, Wang L, Zhang Z, et al. A Loop-Based and AGO-Incorporated Virtual Screening Model Targeting AGO-Mediated miRNA-mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice. Adv Sci (Weinh). 2020;7:1903451 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 4g
| Au C, Furness J, Britt K, Oshchepkova S, Ladumor H, Soo K, et al. Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531. elife. 2020;9: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 5f
| Zhang Y, Liu C, Gao J, Shao S, Cui Y, Yin S, et al. IL-22 promotes tumor growth of breast cancer cells in mice. Aging (Albany NY). 2020;12:13354-13364 pubmed publisher |
- western blot; human; loading ...; fig 4c
| Yin S, Song M, Zhao R, Liu X, Kang W, Lee J, et al. Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo. Front Cell Dev Biol. 2020;8:366 pubmed publisher |
- western blot; mouse; loading ...; fig 7d
| Zhang S, Macias Garcia A, Ulirsch J, Velazquez J, Butty V, Levine S, et al. HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 1e
| Cornell L, Wander S, Visal T, Wagle N, Shapiro G. MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance. Cell Rep. 2019;26:2667-2680.e7 pubmed publisher |
- western blot; mouse; loading ...; fig 4d
| Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep. 2019;26:2434-2450.e6 pubmed publisher |
- western blot; human; loading ...; fig 4e
| Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, et al. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019;442:310-319 pubmed publisher |
- immunohistochemistry - paraffin section; human; loading ...; fig 5d
| Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018;34:411-426.e19 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; loading ...; fig 2g
| Zhou Y, Huang T, Zhang J, Wong C, Zhang B, Dong Y, et al. TEAD1/4 exerts oncogenic role and is negatively regulated by miR-4269 in gastric tumorigenesis. Oncogene. 2017;36:6518-6530 pubmed publisher |
- western blot; human; fig 3d
| Chavali P, Stojic L, Meredith L, Joseph N, Nahorski M, Sanford T, et al. Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication. Science. 2017;357:83-88 pubmed publisher |
- western blot; human; loading ...; fig 2c
| Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4a
| Major J, Dewan A, Salih M, Leddy J, Tuana B. E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PLoS ONE. 2017;12:e0170066 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:700; loading ...; fig 11h
- western blot; mouse; 1:700; loading ...; fig 11a
| Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher |
- western blot; human; loading ...; fig 2
| Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s3b
| Queisser A, Hagedorn S, Wang H, Schaefer T, Konantz M, Alavi S, et al. Ecotropic viral integration site 1, a novel oncogene in prostate cancer. Oncogene. 2017;36:1573-1584 pubmed publisher |
- western blot; mouse; loading ...; fig 1c
| Ramazzotti G, Billi A, Manzoli L, Mazzetti C, Ruggeri A, Erneux C, et al. IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation. Oncotarget. 2016;7:84118-84127 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; fig 4
| Song J, Song L, Herrera A, Venkataraman G, Murata Collins J, Bedell V, et al. Cyclin D1 expression in peripheral T-cell lymphomas. Mod Pathol. 2016;29:1306-1312 pubmed publisher |
- western blot; human; 1:2000; fig 6
| O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed publisher |
- western blot; human; fig 8
| Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s2d
| Guo Z, Kong Q, Liu C, Zhang S, Zou L, Yan F, et al. DCAF1 controls T-cell function via p53-dependent and -independent mechanisms. Nat Commun. 2016;7:10307 pubmed publisher |
- western blot; mouse; 1:1000; fig 2c
| Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher |
- western blot; human; loading ...; fig 6b
| Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
| Marzagalli M, Casati L, Moretti R, Montagnani Marelli M, Limonta P. Estrogen Receptor β Agonists Differentially Affect the Growth of Human Melanoma Cell Lines. PLoS ONE. 2015;10:e0134396 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Yang S, Lin H, Chang V, Chen C, Liu Y, Wang J, et al. Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget. 2015;6:23857-73 pubmed |
- immunohistochemistry; mouse; loading ...; fig 3
| Puzio Kuter A, Laddha S, Castillo Martin M, Sun Y, Cordon Cardo C, Chan C, et al. Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma. Cell Death Differ. 2015;22:1785-91 pubmed publisher |
| Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed publisher |
| Golkowski M, Lius A, Sapre T, Lau H, Moreno T, Maly D, et al. Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity. Mol Cell. 2023;83:803-818.e8 pubmed publisher |
| Sharma P, Alsharif S, Bursch K, Parvathaneni S, Anastasakis D, Chahine J, et al. Keratin 19 regulates cell cycle pathway and sensitivity of breast cancer cells to CDK inhibitors. Sci Rep. 2019;9:14650 pubmed publisher |
| Chiang K, Yeh T, Huang C, Chang Y, Juang H, Cheng C, et al. MART-10 represses cholangiocarcinoma cell growth and high vitamin D receptor expression indicates better prognosis for cholangiocarcinoma. Sci Rep. 2017;7:43773 pubmed publisher |
| Fan Y, Mok C, Chan M, Zhang Y, Nal B, Kien F, et al. Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection. J Biol Chem. 2017;292:5070-5088 pubmed publisher |
| Lee P, Zhu Z, Hachmann J, Nojima T, Kitamura D, Salvesen G, et al. Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation. J Immunol. 2017;198:1066-1080 pubmed publisher |
| Lee J, Park J, Byun J, Kim H, Ryu P, Lee S, et al. Silencing of voltage-gated potassium channel KV9.3 inhibits proliferation in human colon and lung carcinoma cells. Oncotarget. 2015;6:8132-43 pubmed |
| Kang W, Tong J, Lung R, Dong Y, Zhao J, Liang Q, et al. Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma. Mol Cancer. 2015;14:52 pubmed publisher |
| Ishihara S, Yasuda M, Ishizu A, Ishikawa M, Shirato H, Haga H. Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells. Oncotarget. 2015;6:4602-14 pubmed |
| Modelska A, Turro E, Russell R, Beaton J, Sbarrato T, Spriggs K, et al. The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape. Cell Death Dis. 2015;6:e1603 pubmed publisher |
| Faller W, Jackson T, Knight J, Ridgway R, Jamieson T, Karim S, et al. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature. 2015;517:497-500 pubmed publisher |
| Pan W, Cheng Y, Zhang H, Liu B, Mo X, Li T, et al. CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest. Sci Rep. 2014;4:6812 pubmed publisher |
| Scharfmann R, Pechberty S, Hazhouz Y, von Bülow M, Bricout Neveu E, Grenier Godard M, et al. Development of a conditionally immortalized human pancreatic ? cell line. J Clin Invest. 2014;124:2087-98 pubmed publisher |
| Kusama K, Yoshie M, Tamura K, Daikoku T, Takarada T, Tachikawa E. Possible roles of the cAMP-mediators EPAC and RAP1 in decidualization of rat uterus. Reproduction. 2014;147:897-906 pubmed publisher |
| Witt D, Burfeind P, von Hardenberg S, Opitz L, Salinas Riester G, Bremmer F, et al. Valproic acid inhibits the proliferation of cancer cells by re-expressing cyclin D2. Carcinogenesis. 2013;34:1115-24 pubmed publisher |
| Buss H, Handschick K, Jurrmann N, Pekkonen P, Beuerlein K, Müller H, et al. Cyclin-dependent kinase 6 phosphorylates NF-?B P65 at serine 536 and contributes to the regulation of inflammatory gene expression. PLoS ONE. 2012;7:e51847 pubmed publisher |
| Stiles J, Amaya C, Pham R, Rowntree R, Lacaze M, Mulne A, et al. Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis. Exp Ther Med. 2012;4:594-604 pubmed |
| Hoda M, Münzker J, Ghanim B, Schelch K, Klikovits T, Laszlo V, et al. Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells. Br J Cancer. 2012;107:1978-86 pubmed publisher |
| Ramasamy R, Tong C, Yip W, Vellasamy S, Tan B, Seow H. Basic fibroblast growth factor modulates cell cycle of human umbilical cord-derived mesenchymal stem cells. Cell Prolif. 2012;45:132-9 pubmed publisher |
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