product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
EpCAM (VU1D9) Mouse mAb
catalog :
2929
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VU1D9
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3b
Al Khalaf H, Amir M, Al Mohanna F, Tulbah A, Al Sayed A, Aboussekhra A. Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Mol Cell Biol. 2017;37: pubmed publisher
  • flow cytometry; human; loading ...; fig 1a
  • immunocytochemistry; human
Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
  • western blot; human; loading ...; fig 2b
Park S, Kim J, Kim N, Yang K, Shim J, Heo K. Estradiol, TGF-?1 and hypoxia promote breast cancer stemness and EMT-mediated breast cancer migration. Oncol Lett. 2016;11:1895-1902 pubmed
  • immunocytochemistry; human; fig 4
Tsaktanis T, Kremling H, Pavšič M, von Stackelberg R, Mack B, Fukumori A, et al. Cleavage and cell adhesion properties of human epithelial cell adhesion molecule (HEPCAM). J Biol Chem. 2015;290:24574-91 pubmed publisher
  • western blot; human
Nagahara T, Shiraha H, Sawahara H, Uchida D, Takeuchi Y, Iwamuro M, et al. Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells. Oncol Rep. 2015;34:1169-77 pubmed publisher
  • western blot; mouse; 1:2000; fig 5a
Abreu Vieira G, Fischer A, Mattsson C, de Jong J, Shabalina I, Ryden M, et al. Cidea improves the metabolic profile through expansion of adipose tissue. Nat Commun. 2015;6:7433 pubmed publisher
  • flow cytometry; human; loading ...; fig S3
Kishikawa T, Otsuka M, Tan P, Ohno M, Sun X, Yoshikawa T, et al. Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine. Oncotarget. 2015;6:8339-52 pubmed
  • western blot; human; fig 2
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • immunohistochemistry; human; 1:500
Barbera M, Di Pietro M, Walker E, Brierley C, Macrae S, Simons B, et al. The human squamous oesophagus has widespread capacity for clonal expansion from cells at diverse stages of differentiation. Gut. 2015;64:11-9 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Nakanishi Y, Seno H, Fukuoka A, Ueo T, Yamaga Y, Maruno T, et al. Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet. 2013;45:98-103 pubmed publisher
Kosaka T, Hongo H, Oya M. Complete response with early introduction of cabazitaxel in a patient with multiple lung metastases of castration-resistant prostate cancer following the early detection of metastases using liquid biopsy: a case report. BMC Cancer. 2019;19:562 pubmed publisher
Esposito M, Mondal N, Greco T, Wei Y, Spadazzi C, Lin S, et al. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019;21:627-639 pubmed publisher
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, et al. Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures. PLoS Genet. 2019;15:e1008076 pubmed publisher
LI Y, Du L, Wang J, Vega R, Lee T, Miao Y, et al. Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. Cell Chem Biol. 2019;26:278-288.e6 pubmed publisher
Al Khalaf H, Al Harbi B, Al Sayed A, Arafah M, Tulbah A, Jarman A, et al. Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects. Mol Cell Biol. 2019;39: pubmed publisher
Pan M, Schinke H, Luxenburger E, Kranz G, Shakhtour J, Libl D, et al. EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers. PLoS Biol. 2018;16:e2006624 pubmed publisher
Nava Rodrigues D, Rescigno P, Liu D, Yuan W, Carreira S, Lambros M, et al. Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer. J Clin Invest. 2018;128:4441-4453 pubmed publisher
Calcinotto A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, et al. IL-23 secreted by myeloid cells drives castration-resistant prostate cancer. Nature. 2018;559:363-369 pubmed publisher
McKnight K, Xie L, González López O, Rivera Serrano E, Chen X, Lemon S. Protein composition of the hepatitis A virus quasi-envelope. Proc Natl Acad Sci U S A. 2017;114:6587-6592 pubmed publisher
Rolland Fourcade C, Denadai Souza A, Cirillo C, Lopez C, Jaramillo J, Desormeaux C, et al. Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Gut. 2017;66:1767-1778 pubmed publisher
Qin X, Park S, Duffy S, Matthews K, Ang R, Todenhöfer T, et al. Size and deformability based separation of circulating tumor cells from castrate resistant prostate cancer patients using resettable cell traps. Lab Chip. 2015;15:2278-86 pubmed publisher
Al Khalaf H, Aboussekhra A. MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor ZEB1 and the protein kinase AKT. J Biol Chem. 2014;289:31433-47 pubmed publisher
Chen S, Xu X, Wang X, Cui S, Xu L, Jiang Y, et al. Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation. J Proteomics. 2014;110:155-71 pubmed publisher
Driemel C, Kremling H, Schumacher S, Will D, Wolters J, Lindenlauf N, et al. Context-dependent adaption of EpCAM expression in early systemic esophageal cancer. Oncogene. 2014;33:4904-15 pubmed publisher
Luk J, Burchard J, Zhang C, Liu A, Wong K, Shek F, et al. DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem. 2011;286:30706-13 pubmed publisher
product information
SKU :
2929S
Product-Name :
EpCAM (VU1D9) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Flow cytometry
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
40
Host :
Mouse
Target :
EPCAM
Primary-Protein :
EPCAM
Alt-Names :
ACSTD1,Adenocarcinoma-associated antigen,CO-17A,CO17-1A,Cell surface glycoprotein Trop-1,DIAR5,EGP,EGP-2,EGP314,EGP34,EGP40,EPCAM,ESA,Ep-CAM,Epithelial cell adhesion molecule,Epithelial cell surface antigen,Epithelial glycoprotein,Epithelial glycoprotein 314,GA733-2,HNPCC8,KS 1/4 antigen,KS1/4,KSA,M1S2,M4S1,MIC18,MK-1,Major gastrointestinal tumor-associated protein GA733-2,TACST-1,TACSTD1,TROP1,Tumor-associated calcium signal transducer 1,carcinoma-associated antigen GA733-2,hEGP-2,hEGP314,human epithelial glycoprotein-2,membrane component, chromosome 4, surface marker (35kD glycoprotein)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.