product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SOCS3 Antibody
catalog :
2923
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, other
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s8b
Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A. 2018;115:E2801-E2810 pubmed publisher
  • western blot; mouse; fig 2c
Shen Q, Zhang Q, Shi Y, Shi Q, Jiang Y, Gu Y, et al. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. Nature. 2018;554:123-127 pubmed publisher
  • western blot; mouse; loading ...; fig s5d
Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig st2
Liu W, Liu J, Xia J, Xue X, Wang H, Qi Z, et al. Leptin receptor knockout-induced depression-like behaviors and attenuated antidepressant effects of exercise are associated with STAT3/SOCS3 signaling. Brain Behav Immun. 2017;61:297-305 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Long M, Eddy W, Gong K, Lovelace Macon L, McMahan R, Charron J, et al. MEK1/2 Inhibition Promotes Macrophage Reparative Properties. J Immunol. 2017;198:862-872 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Dinger K, Kasper P, Hucklenbruch Rother E, Vohlen C, Jobst E, Janoschek R, et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice. Sci Rep. 2016;6:24168 pubmed publisher
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Nakamura R, Sene A, Santeford A, Gdoura A, Kubota S, Zapata N, et al. IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. Nat Commun. 2015;6:7847 pubmed publisher
  • western blot; mouse
Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed publisher
  • western blot; mouse
Sriram U, Xu J, Chain R, Varghese L, Chakhtoura M, Bennett H, et al. IL-4 suppresses the responses to TLR7 and TLR9 stimulation and increases the permissiveness to retroviral infection of murine conventional dendritic cells. PLoS ONE. 2014;9:e87668 pubmed publisher
Sun Y, Lin Z, Liu C, Gong Y, Liegl R, Fredrick T, et al. Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos. J Exp Med. 2017;214:1753-1767 pubmed publisher
product information
SKU :
2923S
Product-Name :
SOCS3 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
26
Host :
Rabbit
Target :
SOCS3
Primary-Protein :
SOCS3
Alt-Names :
ATOD4,CIS-3,CIS3,Cish3,Cytokine-inducible SH2 protein 3,MGC71791,SOCS-3,SOCS3,SSI-3,SSI3,STAT-induced STAT inhibitor 3,Suppressor of cytokine signaling 3,cytokine-induced SH2 protein 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.