| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 1f
| Han J, Chen X, Xu J, Chu L, Li R, Sun N, et al. Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1. Int J Med Sci. 2021;18:3437-3451 pubmed publisher |
- immunocytochemistry; mouse; 1:2000; loading ...; fig s3d
| Yoshioka K, Nagahisa H, Miura F, Araki H, Kamei Y, Kitajima Y, et al. Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle. Sci Adv. 2021;7: pubmed publisher |
| Xue J, Zhao Y, Aronowitz J, Mai T, Vides A, Qeriqi B, et al. Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition. Nature. 2020;577:421-425 pubmed publisher |
- western blot; human; loading ...; fig 5d, 5c
| Naamati A, Williamson J, Greenwood E, Marelli S, Lehner P, Matheson N. Functional proteomic atlas of HIV infection in primary human CD4+ T cells. elife. 2019;8: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig S6n
| Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 9a
| Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed publisher |
- western blot; human; loading ...; fig 5b
| Fang Y, Kong Y, Xi J, Zhu M, Zhu T, Jiang T, et al. Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Oncotarget. 2016;7:79327-79341 pubmed publisher |
- western blot; human; 1:2000; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 7a
| Unsal E, Degirmenci B, Harmanda B, Erman B, Ozlu N. A small molecule identified through an in silico screen inhibits Aurora B-INCENP interaction. Chem Biol Drug Des. 2016;88:783-794 pubmed publisher |
- western blot; human; fig 6
| Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed publisher |
- western blot; human; 1:1000; fig 3b
| Polacchini A, Albani C, Baj G, Colliva A, Carpinelli P, Tongiorgi E. Combined cisplatin and aurora inhibitor treatment increase neuroblastoma cell death but surviving cells overproduce BDNF. Biol Open. 2016;5:899-907 pubmed publisher |
- western blot; mouse; fig s2
| van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher |
- western blot; human; fig 1
| Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher |
- western blot; human; 1:2000; fig 3
| Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher |
- western blot; mouse; fig 1
- western blot; human; fig 2
| Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider R, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nat Med. 2015;21:1473-80 pubmed publisher |
- proximity ligation assay; mouse; fig 5
| Dumont N, Wang Y, von Maltzahn J, Pasut A, Bentzinger C, Brun C, et al. Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Nat Med. 2015;21:1455-63 pubmed publisher |
- immunocytochemistry; human; 1:500
| Martinez R, Blasina A, Hallin J, Hu W, Rymer I, Fan J, et al. Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility. PLoS ONE. 2015;10:e0138616 pubmed publisher |
- immunocytochemistry; mouse; fig 7
- western blot; mouse; fig 7
| Hu M, Wang Z, Teng Y, Jiang Z, Ma X, Hou N, et al. Loss of protein phosphatase 6 in oocytes causes failure of meiosis II exit and impaired female fertility. J Cell Sci. 2015;128:3769-80 pubmed publisher |
- other; mouse; 1:500; fig s1
| Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
| Hasegawa H, Ishibashi K, Kubota S, Yamaguchi C, Yuki R, Nakajo H, et al. Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase. PLoS ONE. 2014;9:e116048 pubmed publisher |
| Choi M, Kim W, Cheon M, Lee C, Kim J. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells. Cancer Lett. 2015;357:591-601 pubmed publisher |
- flow cytometry; human; fig 5
| Gustafson W, Meyerowitz J, Nekritz E, Chen J, Benes C, Charron E, et al. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 2014;26:414-427 pubmed publisher |
- western blot; pigs ; fig 4
| Komrskova P, Susor A, Malik R, Procházková B, Liskova L, Supolikova J, et al. Aurora kinase A is not involved in CPEB1 phosphorylation and cyclin B1 mRNA polyadenylation during meiotic maturation of porcine oocytes. PLoS ONE. 2014;9:e101222 pubmed publisher |
- flow cytometry; mouse; 1:200
| Shenje L, Andersen P, Halushka M, Lui C, Fernandez L, Collin G, et al. Mutations in Alström protein impair terminal differentiation of cardiomyocytes. Nat Commun. 2014;5:3416 pubmed publisher |
- western blot; human; fig 1c
| Lin Y, Richards F, Krippendorff B, Bramhall J, Harrington J, Bapiro T, et al. Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells. Br J Cancer. 2012;107:1692-701 pubmed publisher |
- western blot; fission yeast
| Koch A, Rode H, Richters A, Rauh D, Hauf S. A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase. ACS Chem Biol. 2012;7:723-31 pubmed publisher |
| Orienti I, Francescangeli F, De Angelis M, Fecchi K, Bongiorno Borbone L, Signore M, et al. A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors. Cell Death Dis. 2019;10:529 pubmed publisher |
| Fang H, Niu K, Mo D, Zhu Y, Tan Q, Wei D, et al. RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity. Oncogenesis. 2018;7:68 pubmed publisher |
| Burgess S, Mukherjee M, Sabir S, Joseph N, Gutiérrez Caballero C, Richards M, et al. Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix. EMBO J. 2018;37: pubmed publisher |
| Li D, Ren Z. Cordyceps sinensis promotes immune regulation and enhances bacteriostatic activity of PA-824 via IL-10 in Mycobacterium tuberculosis disease. Braz J Med Biol Res. 2017;50:e6188 pubmed publisher |
| Noguchi K, Hongama K, Hariki S, Nonomiya Y, Katayama K, Sugimoto Y. Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy. J Biol Chem. 2017;292:1910-1924 pubmed publisher |
| Larsen S, Yde C, Laenkholm A, Rasmussen B, Duun Henriksen A, Bak M, et al. Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer. BMC Cancer. 2015;15:239 pubmed publisher |
| Zuazua Villar P, Rodriguez R, Gagou M, Eyers P, Meuth M. DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B. Cell Death Dis. 2014;5:e1253 pubmed publisher |
| Soeda S, Nakayama Y, Honda T, Aoki A, Tamura N, Abe K, et al. v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure. Exp Cell Res. 2013;319:1382-97 pubmed publisher |
| Matsui Y, Nakayama Y, Okamoto M, Fukumoto Y, Yamaguchi N. Enrichment of cell populations in metaphase, anaphase, and telophase by synchronization using nocodazole and blebbistatin: a novel method suitable for examining dynamic changes in proteins during mitotic progression. Eur J Cell Biol. 2012;91:413-9 pubmed publisher |
| Cheung C, Lin W, Hsu J, Hour T, Yeh T, Ko S, et al. BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells. PLoS ONE. 2011;6:e23485 pubmed publisher |
| Recino A, Sherwood V, Flaxman A, Cooper W, Latif F, Ward A, et al. Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis. Biochem J. 2010;430:207-13 pubmed publisher |
