product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CDK4 (DCS156) Mouse mAb
catalog :
2906P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
mouse
clone name :
DCS156

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot
citations: 9
Published Application/Species/DilutionReference
  • western blot; human; fig 4
Chiang K, Chen H, Hsu S, Pang J, Wang S, Hsu J, et al. PTEN insufficiency modulates ER+ breast cancer cell cycle progression and increases cell growth in vitro and in vivo. Drug Des Devel Ther. 2015;9:4631-8 pubmed publisher
  • western blot; human
van der Linden M, Willekes M, van Roon E, Seslija L, Schneider P, Pieters R, et al. MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL. Cell Cycle. 2014;13:834-44 pubmed publisher
  • western blot; human; 1:500
Malaviya A, Sylvester P. Synergistic Antiproliferative Effects of Combined γ -Tocotrienol and PPAR γ Antagonist Treatment Are Mediated through PPAR γ -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146 pubmed publisher
Xu Y, Luo Q, Lin T, Zeng Z, Wang G, Zeng D, et al. U12, a UDCA derivative, acts as an anti-hepatoma drug lead and inhibits the mTOR/S6K1 and cyclin/CDK complex pathways. PLoS ONE. 2014;9:e113479 pubmed publisher
Al-Moujahed A, Nicolaou F, Brodowska K, Papakostas T, Marmalidou A, Ksander B, et al. Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase. Invest Ophthalmol Vis Sci. 2014;55:4175-85 pubmed publisher
Chang S, Chang C, Lee D, Lee P, Yeh Y, Yeh C, et al. Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad. Proc Natl Acad Sci U S A. 2008;105:3927-32 pubmed publisher
Nakles R, Kallakury B, Furth P. The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. Am J Pathol. 2013;182:1976-85 pubmed publisher
Adon A, Zeng X, Harrison M, Sannem S, Kiyokawa H, Kaldis P, et al. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells. Mol Cell Biol. 2010;30:694-710 pubmed publisher
Dai Y, Liu L, Zeng T, Zhu Y, Li J, Chen L, et al. Characterization of the oncogenic function of centromere protein F in hepatocellular carcinoma. Biochem Biophys Res Commun. 2013;436:711-8 pubmed publisher
product information
SKU :
2906P
Product-Name :
CDK4 (DCS156) Mouse mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M
Applications :
Western blot
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
30
Host :
Mouse
Target :
Cdk4
Primary-Protein :
CDK4
Alt-Names :
CDK4,CMM3,Cell division protein kinase 4,Cyclin-dependent kinase 4,MGC14458,PSK-J3,cell division kinase 4,melanoma cutaneous malignant, 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.