product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p18 INK4C (DCS118) Mouse mAb
catalog :
2896
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DCS118
reactivity :
human
application :
western blot, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3b
Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher
  • western blot; human; loading ...; fig 2c
Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
  • western blot; human; 1:250; loading ...; fig 1c
Nuzzo A, Giuffrida D, Masturzo B, Mele P, Piccoli E, Eva C, et al. Altered expression of G1/S phase cell cycle regulators in placental mesenchymal stromal cells derived from preeclamptic pregnancies with fetal-placental compromise. Cell Cycle. 2017;16:200-212 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3b
Queisser A, Hagedorn S, Wang H, Schaefer T, Konantz M, Alavi S, et al. Ecotropic viral integration site 1, a novel oncogene in prostate cancer. Oncogene. 2017;36:1573-1584 pubmed publisher
  • western blot; human; fig 8
Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  • western blot; human; fig 7
Ittig S, Schmutz C, Kasper C, Amstutz M, Schmidt A, Sauteur L, et al. A bacterial type III secretion-based protein delivery tool for broad applications in cell biology. J Cell Biol. 2015;211:913-31 pubmed publisher
  • western blot; human
Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed publisher
Moreno Lorenzana D, Avilés Vazquez S, Sandoval Esquivel M, Alvarado Moreno A, Ortiz Navarrete V, Torres Martínez H, et al. CDKIs p18(INK4c) and p57(Kip2) are involved in quiescence of CML leukemic stem cells after treatment with TKI. Cell Cycle. 2016;15:1276-87 pubmed publisher
Yang L, Liu Z, Wu R, Yao Q, Gu Z, Liu M. Correlation of C-X-C chemokine receptor 2 upregulation with poor prognosis and recurrence in human glioma. Onco Targets Ther. 2015;8:3203-9 pubmed publisher
Gao H, Teng C, Huang W, Peng J, Wang C. SOX2 Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3/HIF-α Signaling. Int J Mol Sci. 2015;16:21643-57 pubmed publisher
product information
SKU :
2896P
Product-Name :
p18 INK4C (DCS118) Mouse mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
18
Host :
Mouse
Target :
INK4C, p18
Primary-Protein :
CDKN2C
Alt-Names :
CDK6 inhibitor p18,CDKN2C,CDKN6,CDN2C,Cyclin-dependent kinase 4 inhibitor C,Cyclin-dependent kinase 6 inhibitor,INK4C,cyclin-dependent inhibitor,cyclin-dependent kinase 6 inhibitor p18,cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4),p18,p18-INK4c,p18-INK6
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.