product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-c-Abl (Tyr245) (73E5) Rabbit mAb
catalog :
2868
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
73E5
reactivity :
human, mouse
application :
western blot, immunocytochemistry
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s3c
  • western blot; mouse; fig s3b
Reckel S, Hamelin R, Georgeon S, Armand F, Jolliet Q, Chiappe D, et al. Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics. Leukemia. 2017;31:1502-1512 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5
Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  • western blot; human; 1:500-1:1000
Lupino E, Ramondetti C, Buccinnà B, Piccinini M. Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. Biochem Pharmacol. 2014;92:235-50 pubmed publisher
Dixon A, Pendley S, Bruno B, Woessner D, Shimpi A, Cheatham T, et al. Disruption of Bcr-Abl coiled coil oligomerization by design. J Biol Chem. 2011;286:27751-60 pubmed publisher
product information
SKU :
2868S
Product-Name :
Phospho-c-Abl (Tyr245) (73E5) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M)
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
135 (c-Abl); 210 (Bcr-Abl)
Host :
Rabbit
Target :
Abl1 (Tyr226) phosphate
Primary-Protein :
Abl
Alt-Names :
ABL,ABL1,Abelson murine leukemia viral oncogene homolog 1,JTK7,Proto-oncogene c-Abl,Tyrosine-protein kinase ABL1,bcr/abl,bcr/c-abl oncogene protein,c-ABL,c-abl oncogene 1, receptor tyrosine kinase,p150,proto-oncogene tyrosine-protein kinase ABL1,v-abl,v-abl Abelson murine leukemia viral oncogene homolog 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.