Phospho-c-Abl (Tyr412) (247C7) Rabbit mAb | Cell Signaling Technology 2865 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-c-Abl (Tyr412) (247C7) Rabbit mAb

catalog :

2865

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

247C7

reactivity :

human, mouse

application :

western blot

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 4b	Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed publisher
western blot; mouse; loading ...; fig s8d	Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed publisher
western blot; mouse; fig 4c	Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
western blot; mouse; fig s3b western blot; human; loading ...; fig s3b	Reckel S, Hamelin R, Georgeon S, Armand F, Jolliet Q, Chiappe D, et al. Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics. Leukemia. 2017;31:1502-1512 pubmed publisher
western blot; human; fig 1a	Eiring A, Khorashad J, Anderson D, Yu F, Redwine H, Mason C, et al. Î²-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia. Leukemia. 2015;29:2328-37 pubmed publisher
western blot; human; loading ...; fig 3c	Fahrenkamp D, de Leur H, KÃ¼ster A, Chatain N, MÃ¼ller Newen G. Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction. Cell Commun Signal. 2015;13:10 pubmed publisher
western blot; human; loading ...; fig 4b	Nasr R, Hmadi R, El Eit R, Iskandarani A, Jabbour M, Zaatari G, et al. ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model. Int J Cancer. 2015;137:698-709 pubmed publisher
western blot; human; 1:1000	Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
	O Hare T, Zabriskie M, Eide C, Agarwal A, Adrian L, You H, et al. The BCR-ABL35INS insertion/truncation mutant is kinase-inactive and does not contribute to tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Blood. 2011;118:5250-4 pubmed publisher
	Goss V, Lee K, Moritz A, Nardone J, Spek E, Macneill J, et al. A common phosphotyrosine signature for the Bcr-Abl kinase. Blood. 2006;107:4888-97 pubmed

product information

SKU :

2865S

Product-Name :

Phospho-c-Abl (Tyr412) (247C7) Rabbit mAb

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, (M)

Applications :

Western blot

Product-Category :

MAP Kinase Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

135 (c-Abl); 210 (Bcr-Abl)

Host :

Rabbit

Target :

Abl1 (Tyr393) phosphate

Primary-Protein :

Abl

Alt-Names :

ABL,ABL1,Abelson murine leukemia viral oncogene homolog 1,JTK7,Proto-oncogene c-Abl,Tyrosine-protein kinase ABL1,bcr/abl,bcr/c-abl oncogene protein,c-ABL,c-abl oncogene 1, receptor tyrosine kinase,p150,proto-oncogene tyrosine-protein kinase ABL1,v-abl,v-abl Abelson murine leukemia viral oncogene homolog 1

more info or order :

Cell Signaling Technology product webpage