product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Abl Antibody
catalog :
2862
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, other
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s1b
Amado Azevedo J, van Stalborch A, Valent E, Nawaz K, van Bezu J, Eringa E, et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation. Angiogenesis. 2021;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5f
  • western blot; mouse; 1:1000; loading ...; fig s11b
Zhou H, Qin L, Jiang Q, Murray K, Zhang H, Li B, et al. Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. Nat Commun. 2021;12:504 pubmed publisher
  • western blot; mouse; loading ...; fig 4k
Zhao X, Xie H, Zhao M, Ahsan A, Li X, Wang F, et al. Fc receptor-like 1 intrinsically recruits c-Abl to enhance B cell activation and function. Sci Adv. 2019;5:eaaw0315 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 2a
Chen C, Zhuang Y, Chen X, Chen X, Li D, Fan Y, et al. Hsp90 N- and C-terminal double inhibition synergistically suppresses Bcr-Abl-positive human leukemia cells. Oncotarget. 2017;8:10025-10036 pubmed publisher
  • western blot; human; loading ...; fig 1b
Shi D, Liu Y, Xi R, Zou W, Wu L, Zhang Z, et al. Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells. Int J Nanomedicine. 2016;11:5823-5835 pubmed
  • western blot; human; fig 5
Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
  • western blot; human; 1:3000; fig 8
Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Wu R, Chen H, Ma J, He Q, Huang Q, Liu Q, et al. c-Abl-p38α signaling plays an important role in MPTP-induced neuronal death. Cell Death Differ. 2016;23:542-52 pubmed publisher
Leblanc A, Sprowl J, Alberti P, Chiorazzi A, Arnold W, Gibson A, et al. OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity. J Clin Invest. 2018;128:816-825 pubmed publisher
Wang Y, Hall R, Lee M, Kamgar Parsi A, Bi X, Baudry M. The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Sci Rep. 2017;7:11771 pubmed publisher
Rauzan M, Chuah C, Ko T, Ong S. The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia. PLoS ONE. 2017;12:e0174107 pubmed publisher
Ouellette S, Noel B, Parker L. A Cell-Based Assay for Measuring Endogenous BcrAbl Kinase Activity and Inhibitor Resistance. PLoS ONE. 2016;11:e0161748 pubmed publisher
Chakraborty S, Leng X, Perazzona B, Sun X, Lin Y, Arlinghaus R. Combination of JAK2 and HSP90 inhibitors: an effective therapeutic option in drug-resistant chronic myelogenous leukemia. Genes Cancer. 2016;7:201-208 pubmed publisher
Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed publisher
product information
SKU :
2862P
Product-Name :
c-Abl Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
135 (c-Abl); 210 (Bcr-Abl)
Host :
Rabbit
Target :
Abl1
Primary-Protein :
Abl
Alt-Names :
ABL,ABL1,Abelson murine leukemia viral oncogene homolog 1,JTK7,Proto-oncogene c-Abl,Tyrosine-protein kinase ABL1,bcr/abl,bcr/c-abl oncogene protein,c-ABL,c-abl oncogene 1, receptor tyrosine kinase,p150,proto-oncogene tyrosine-protein kinase ABL1,v-abl,v-abl Abelson murine leukemia viral oncogene homolog 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.