Phospho-c-Abl (Tyr245) Antibody | Cell Signaling Technology 2861 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-c-Abl (Tyr245) Antibody

catalog :

2861

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, other

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1f	Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed publisher
western blot; human; loading ...; fig 4c western blot; mouse; fig 1f	Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 1g western blot; mouse; loading ...; fig 1a, 1c	Brahmachari S, Ge P, Lee S, Kim D, Karuppagounder S, Kumar M, et al. Activation of tyrosine kinase c-Abl contributes to ?-synuclein-induced neurodegeneration. J Clin Invest. 2016;126:2970-88 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3a	Ko T, Chin H, Chuah C, Huang J, Ng K, Khaw S, et al. The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia. Oncotarget. 2016;7:2721-33 pubmed publisher
western blot; mouse; loading ...; fig 1a	Wu R, Chen H, Ma J, He Q, Huang Q, Liu Q, et al. c-Abl-p38Î± signaling plays an important role in MPTP-induced neuronal death. Cell Death Differ. 2016;23:542-52 pubmed publisher
ELISA; human	Skora L, Kempf D, Mestan J, D Orazio D, Jahnke W. Phosphorylation of Tyr245 in the open-inhibited state of Abelson kinase does not induce downstream signaling. Eur J Haematol. 2016;96:502-6 pubmed publisher
other; mouse; 1:1000; fig s1	Chiang C, Uzoma I, Lane D, MemiÅ¡eviÄ‡ V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
	Wang Z, Kim M, Martinez Ferrando I, Koleske A, Pandey A, Cole P. Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018;57:1390-1398 pubmed publisher
	Wang Y, Hall R, Lee M, Kamgar Parsi A, Bi X, Baudry M. The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation. Sci Rep. 2017;7:11771 pubmed publisher
	Obr A, RÃ¶selovÃ¡ P, GrebeÅˆovÃ¡ D, KuÅ¾elovÃ¡ K. Real-time analysis of imatinib- and dasatinib-induced effects on chronic myelogenous leukemia cell interaction with fibronectin. PLoS ONE. 2014;9:e107367 pubmed publisher
	Khusial P, Vadla B, Krishnan H, Ramlall T, Shen Y, Ichikawa H, et al. Src activates Abl to augment Robo1 expression in order to promote tumor cell migration. Oncotarget. 2010;1:198-209 pubmed
	Ganapathipillai S, Medová M, Aebersold D, Manley P, Berthou S, Streit B, et al. Coupling of mutated Met variants to DNA repair via Abl and Rad51. Cancer Res. 2008;68:5769-77 pubmed publisher

product information

SKU :

2861S

Product-Name :

Phospho-c-Abl (Tyr245) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, (M)

Applications :

Western blot

Product-Category :

MAP Kinase Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

135 (c-Abl); 210 (Bcr-Abl)

Host :

Rabbit

Target :

Abl1 (Tyr226) phosphate

Primary-Protein :

Abl

Alt-Names :

ABL,ABL1,Abelson murine leukemia viral oncogene homolog 1,JTK7,Proto-oncogene c-Abl,Tyrosine-protein kinase ABL1,bcr/abl,bcr/c-abl oncogene protein,c-ABL,c-abl oncogene 1, receptor tyrosine kinase,p150,proto-oncogene tyrosine-protein kinase ABL1,v-abl,v-abl Abelson murine leukemia viral oncogene homolog 1

more info or order :

Cell Signaling Technology product webpage