4E-BP2 Antibody | Cell Signaling Technology 2845 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

4E-BP2 Antibody

catalog :

2845

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, western blot knockout validation, immunohistochemistry knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; loading ...; fig 5a	Roque P, Hooshmandi M, Neagu Lund L, Yin S, Yousefpour N, Sato H, et al. Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1. Sci Rep. 2021;11:15490 pubmed publisher
immunohistochemistry knockout validation; mouse; 1:400; loading ...; fig 2a immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 2a western blot; mouse; loading ...; fig 1h	Sharma V, Sood R, Lou D, Hung T, Levesque M, Han Y, et al. 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
western blot; mouse; 1:1000; fig 2e	Vinsland E, Baskaran P, Mihaylov S, Hobbs C, Wood H, Bouybayoune I, et al. The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021;11:16299 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 1b	William M, Leroux L, Chaparro V, Graber T, Alain T, Jaramillo M. Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells. Eur J Immunol. 2019;49:1200-1212 pubmed publisher
western blot; mouse; loading ...; fig s2a	Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
western blot; mouse; loading ...; fig 1e	Diez H, Benitez M, Fernandez S, Torres Aleman I, Garrido J, Wandosell F. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation. Biochim Biophys Acta. 2016;1863:2574-2583 pubmed publisher
	Zaini M, Muller C, Ackermann T, Reinshagen J, Kortman G, Pless O, et al. A screening strategy for the discovery of drugs that reduce C/EBPβ-LIP translation with potential calorie restriction mimetic properties. Sci Rep. 2017;7:42603 pubmed publisher
	Tsukumo Y, Alain T, Fonseca B, Nadon R, Sonenberg N. Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3. Nat Commun. 2016;7:11776 pubmed publisher
	Millican Slater R, Sayers C, Hanby A, Hughes T. Expression of phosphorylated eIF4E-binding protein 1, but not of eIF4E itself, predicts survival in male breast cancer. Br J Cancer. 2016;115:339-45 pubmed publisher

product information

SKU :

2845P

Product-Name :

4E-BP2 Antibody

Size :

40 ul

Price-(USD) :

123 USD

Species-x-Reactivity :

H, M, R, Mk, B

Applications :

Flow cytometry

Product-Category :

Translational Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

15 to 20

Host :

Rabbit

Target :

4E-BP2

Primary-Protein :

4E-BP2

Alt-Names :

4E-BP2,4EBP2,EIF4EBP2,Eukaryotic translation initiation factor 4E-binding protein 2,PHASII,eIF4E-binding protein 2,eukaryotic translation initiation factor 4E binding protein 2,phosphorylated, heat and acid stable regulated by insulin protein II

more info or order :

Cell Signaling Technology product webpage