product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PLCγ1 Antibody
catalog :
2822
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, other
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3a
Yang G, Zhao Z, Qin T, Wang D, Chen L, Xiang R, et al. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation. FASEB J. 2017;31:2001-2012 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • other; human; 1:50; fig 3b
  • western blot; human; 1:1000; fig 3a
Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed publisher
  • western blot; human; 1:1000; fig 6
  • western blot; mouse; 1:1000; fig 8
Blas Rus N, Bustos Morán E, Perez de Castro I, de Carcer G, Borroto A, Camafeita E, et al. Aurora A drives early signalling and vesicle dynamics during T-cell activation. Nat Commun. 2016;7:11389 pubmed publisher
  • western blot; human; fig 2
Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher
  • western blot; human; fig 1
Gramolelli S, Weidner Glunde M, Abere B, Viejo Borbolla A, Bala K, Rückert J, et al. Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells. PLoS Pathog. 2015;11:e1005105 pubmed publisher
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; mouse; 1:1000; fig 7g
He C, Medley S, Hu T, Hinsdale M, Lupu F, Virmani R, et al. PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun. 2015;6:7770 pubmed publisher
  • immunocytochemistry; human
  • western blot; human; 1:1000
Takagishi T, Oda M, Kabura M, Kurosawa M, Tominaga K, Urano S, et al. Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane. PLoS ONE. 2015;10:e0120497 pubmed publisher
  • western blot; human; 1:1000; fig 6
Leung C, Yeung T, Yip K, Pradeep S, Balasubramanian L, Liu J, et al. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014;5:5092 pubmed publisher
  • western blot; human; 1:2000; fig 6
Lu H, Clauser K, Tam W, Fröse J, Ye X, Eaton E, et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2014;16:1105-17 pubmed publisher
  • western blot; human; 1:1000; tbl 4
Cox S. Intracellular signaling of CTLs. Methods Mol Biol. 2014;1186:49-63 pubmed publisher
Westernberg L, Conche C, Huang Y, Rigaud S, Deng Y, Siegemund S, et al. Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent. elife. 2016;5: pubmed publisher
Lin C, Chen P, Lein M, Tsao C, Huang C, Wang S, et al. WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells. Oncotarget. 2016;7:9993-10005 pubmed publisher
Doyle J, Doyle A, Wilson N, Habashi J, Bedja D, Whitworth R, et al. A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome. elife. 2015;4: pubmed publisher
Chuang J, Chen P, Tsao C, Chang A, Lein M, Lin C, et al. WISP-1 a novel angiogenic regulator of the CCN family promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression. Oncotarget. 2015;6:4239-52 pubmed
Zeng G, Cui X, Liu Z, Zhao H, Zheng X, Zhang B, et al. Disruption of phosphoinositide-specific phospholipases C?1 contributes to extracellular matrix synthesis of human osteoarthritis chondrocytes. Int J Mol Sci. 2014;15:13236-46 pubmed publisher
Huang X, Sun D, Pan Q, Wen W, Chen Y, Xin X, et al. JG6, a novel marine-derived oligosaccharide, suppresses breast cancer metastasis via binding to cofilin. Oncotarget. 2014;5:3568-78 pubmed
Lee J, Hong W, Majeti R, Stearns T. Centrosome-kinase fusions promote oncogenic signaling and disrupt centrosome function in myeloproliferative neoplasms. PLoS ONE. 2014;9:e92641 pubmed publisher
Wilson T, Garner L, Metcalfe C, King E, Margraf S, Brown M. Fine specificity and molecular competition in SLAM family receptor signalling. PLoS ONE. 2014;9:e92184 pubmed publisher
Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, et al. Differential function of Themis CABIT domains during T cell development. PLoS ONE. 2014;9:e89115 pubmed publisher
Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn G, Ueyama T, et al. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell. 2013;24:1700-12, S1-7 pubmed publisher
Bala K, Bosco R, Gramolelli S, Haas D, Kati S, Pietrek M, et al. Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLC?1 and activating NFAT1-dependent RCAN1 expression. PLoS Pathog. 2012;8:e1002927 pubmed publisher
Dellinger M, Brekken R. Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. PLoS ONE. 2011;6:e28947 pubmed publisher
Maragno A, Pironin M, Alcalde H, Cong X, Knobeloch K, Tangy F, et al. ISG15 modulates development of the erythroid lineage. PLoS ONE. 2011;6:e26068 pubmed publisher
Schoenherr C, Weiskirchen R, Haan S. Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses. Cell Commun Signal. 2010;8:19 pubmed publisher
product information
SKU :
2822S
Product-Name :
PLCγ1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Ca, cAMP and Lipid Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
155
Host :
Rabbit
Target :
PLCg1
Primary-Protein :
PLCG1
Alt-Names :
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1,NCKAP3,PLC-148,PLC-II,PLC-gamma-1,PLC1,PLC148,PLCG1,PLCgamma1,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,Phospholipase C-gamma-1,inositoltrisphosphohydrolase,monophosphatidylinositol phosphodiesterase,phosphatidylinositol phospholipase C,phosphoinositidase C,phosphoinositide phospholipase C,phospholipase C, gamma 1,phospholipase C, gamma 1 (formerly subtype 148),phospholipase C-148,triphosphoinositide phosphodiesterase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.